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dpavlin |
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<!--Section Begins--><br> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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<b>BENZAPEN</b><b><sup>®</sup></b> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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<i>injection suspension</i> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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<b><i>Composition</i></b> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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1 mL contains: |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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Benzathine benzylpenicillin 150,000 iu |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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Procaine benzylpenicillin 150,000 iu |
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</p> |
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</div> |
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</p> |
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<b><i>Action</i></b><b></b> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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Benzapen<b><sup>®</sup></b> is a sterile ready-to-use penicillin suspension. A combined action of procaine benzylpenicillin and benzathine benzylpenicillin ensures efficient blood levels of the drug and its prolonged action. Therapeutic concentrations after a single injection of Benzapen<b><sup>®</sup></b> are maintained over 3-4 days. Owing to these properties usually one injection is sufficient for treatment, which makes Benzapen<b><sup>®</sup></b> a very suitable and cost-effective drug in veterinary practice. |
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</p> |
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</div> |
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</p> |
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</div> |
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<b><i>Indications</i></b> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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General and local infections caused by penicillin-sensitive pathogens, particularly streptococci and staphylococci, diplococci and pneumococci; |
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</p> |
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</div> |
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</p> |
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</div> |
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specific infections: swine erysipelas, anthrax, leptospirosis, malignant edema, tetanus and actinomycosis; |
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bacterial infections secondary to and following viral diseases (viral bronchopneumonia, equine influenza, canine distemper, etc.); |
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puerperal infections, metritis, mastitis, phlegmona, pyodermia, abscess, infected wounds, burns, paronychia, acute suppurative arthritis and umbilical infections. |
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</p> |
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In prophylaxis Benzapen<b><sup>®</sup></b> is given prior to surgical operations and parturition. |
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</p> |
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</div> |
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<b><i>Contraindications</i></b><b></b> |
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</p> |
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</div> |
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Benzapen<b><sup>®</sup></b> should not be administered by i. v. route. |
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</div> |
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</p> |
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</div> |
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Hypersensitivity to penicillin antibiotics, which is quite uncommon. |
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</p> |
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</div> |
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</p> |
| 510 |
|
|
</div> |
| 511 |
|
|
|
| 512 |
|
|
|
| 513 |
|
|
|
| 514 |
|
|
|
| 515 |
|
|
|
| 516 |
|
|
|
| 517 |
|
|
|
| 518 |
|
|
|
| 519 |
|
|
|
| 520 |
|
|
|
| 521 |
|
|
|
| 522 |
|
|
|
| 523 |
|
|
<div align="justify"> |
| 524 |
|
|
<p style="text-align: justify;"> |
| 525 |
|
|
|
| 526 |
|
|
Beta-lactam antibiotics should not be administered to guinea-pigs, hamsters, rabbits and other small monogastric herbivore in which they can cause clostridiotoxicosis and fatal entercholitis. |
| 527 |
|
|
|
| 528 |
|
|
</p> |
| 529 |
|
|
</div> |
| 530 |
|
|
|
| 531 |
|
|
|
| 532 |
|
|
|
| 533 |
|
|
|
| 534 |
|
|
|
| 535 |
|
|
|
| 536 |
|
|
|
| 537 |
|
|
|
| 538 |
|
|
|
| 539 |
|
|
|
| 540 |
|
|
|
| 541 |
|
|
|
| 542 |
|
|
<div align="justify"> |
| 543 |
|
|
<p style="text-align: justify;"> |
| 544 |
|
|
|
| 545 |
|
|
|
| 546 |
|
|
|
| 547 |
|
|
</p> |
| 548 |
|
|
</div> |
| 549 |
|
|
|
| 550 |
|
|
|
| 551 |
|
|
|
| 552 |
|
|
|
| 553 |
|
|
|
| 554 |
|
|
|
| 555 |
|
|
|
| 556 |
|
|
|
| 557 |
|
|
|
| 558 |
|
|
|
| 559 |
|
|
|
| 560 |
|
|
|
| 561 |
|
|
<div align="justify"> |
| 562 |
|
|
<p style="text-align: justify;"> |
| 563 |
|
|
|
| 564 |
|
|
<b><i>Administration and dosage</i></b> |
| 565 |
|
|
|
| 566 |
|
|
</p> |
| 567 |
|
|
</div> |
| 568 |
|
|
|
| 569 |
|
|
|
| 570 |
|
|
|
| 571 |
|
|
|
| 572 |
|
|
|
| 573 |
|
|
|
| 574 |
|
|
|
| 575 |
|
|
|
| 576 |
|
|
|
| 577 |
|
|
|
| 578 |
|
|
|
| 579 |
|
|
|
| 580 |
|
|
<div align="justify"> |
| 581 |
|
|
<p style="text-align: justify;"> |
| 582 |
|
|
|
| 583 |
|
|
Shake well before use. |
| 584 |
|
|
|
| 585 |
|
|
</p> |
| 586 |
|
|
</div> |
| 587 |
|
|
|
| 588 |
|
|
|
| 589 |
|
|
|
| 590 |
|
|
|
| 591 |
|
|
|
| 592 |
|
|
|
| 593 |
|
|
|
| 594 |
|
|
|
| 595 |
|
|
|
| 596 |
|
|
|
| 597 |
|
|
|
| 598 |
|
|
|
| 599 |
|
|
<div align="justify"> |
| 600 |
|
|
<p style="text-align: justify;"> |
| 601 |
|
|
|
| 602 |
|
|
Benzapen<b><sup>®</sup></b> is given by i. m. route only. |
| 603 |
|
|
|
| 604 |
|
|
</p> |
| 605 |
|
|
</div> |
| 606 |
|
|
|
| 607 |
|
|
|
| 608 |
|
|
|
| 609 |
|
|
|
| 610 |
|
|
|
| 611 |
|
|
|
| 612 |
|
|
|
| 613 |
|
|
|
| 614 |
|
|
|
| 615 |
|
|
|
| 616 |
|
|
|
| 617 |
|
|
|
| 618 |
|
|
<div align="justify"> |
| 619 |
|
|
<p style="text-align: justify;"> |
| 620 |
|
|
|
| 621 |
|
|
|
| 622 |
|
|
|
| 623 |
|
|
</p> |
| 624 |
|
|
</div> |
| 625 |
|
|
|
| 626 |
|
|
|
| 627 |
|
|
|
| 628 |
|
|
|
| 629 |
|
|
|
| 630 |
|
|
|
| 631 |
|
|
|
| 632 |
|
|
|
| 633 |
|
|
|
| 634 |
|
|
|
| 635 |
|
|
|
| 636 |
|
|
|
| 637 |
|
|
<div align="justify"> |
| 638 |
|
|
<p style="text-align: justify;"> |
| 639 |
|
|
|
| 640 |
|
|
Horses, cattle, sheep, goats and swine: 1 mL/25 kg of b. w. (11,000 iu/kg of b. w.). |
| 641 |
|
|
|
| 642 |
|
|
</p> |
| 643 |
|
|
</div> |
| 644 |
|
|
|
| 645 |
|
|
|
| 646 |
|
|
|
| 647 |
|
|
|
| 648 |
|
|
|
| 649 |
|
|
|
| 650 |
|
|
|
| 651 |
|
|
|
| 652 |
|
|
|
| 653 |
|
|
|
| 654 |
|
|
|
| 655 |
|
|
|
| 656 |
|
|
<div align="justify"> |
| 657 |
|
|
<p style="text-align: justify;"> |
| 658 |
|
|
|
| 659 |
|
|
|
| 660 |
|
|
|
| 661 |
|
|
</p> |
| 662 |
|
|
</div> |
| 663 |
|
|
|
| 664 |
|
|
|
| 665 |
|
|
|
| 666 |
|
|
|
| 667 |
|
|
|
| 668 |
|
|
|
| 669 |
|
|
|
| 670 |
|
|
|
| 671 |
|
|
|
| 672 |
|
|
|
| 673 |
|
|
|
| 674 |
|
|
|
| 675 |
|
|
<div align="justify"> |
| 676 |
|
|
<p style="text-align: justify;"> |
| 677 |
|
|
|
| 678 |
|
|
Dogs and cats: 1 mL/10 kg of b. w. (28,750 iu/kg of b. w.). |
| 679 |
|
|
|
| 680 |
|
|
</p> |
| 681 |
|
|
</div> |
| 682 |
|
|
|
| 683 |
|
|
|
| 684 |
|
|
|
| 685 |
|
|
|
| 686 |
|
|
|
| 687 |
|
|
|
| 688 |
|
|
|
| 689 |
|
|
|
| 690 |
|
|
|
| 691 |
|
|
|
| 692 |
|
|
|
| 693 |
|
|
|
| 694 |
|
|
<div align="justify"> |
| 695 |
|
|
<p style="text-align: justify;"> |
| 696 |
|
|
|
| 697 |
|
|
|
| 698 |
|
|
|
| 699 |
|
|
</p> |
| 700 |
|
|
</div> |
| 701 |
|
|
|
| 702 |
|
|
|
| 703 |
|
|
|
| 704 |
|
|
|
| 705 |
|
|
|
| 706 |
|
|
|
| 707 |
|
|
|
| 708 |
|
|
|
| 709 |
|
|
|
| 710 |
|
|
|
| 711 |
|
|
|
| 712 |
|
|
|
| 713 |
|
|
<div align="justify"> |
| 714 |
|
|
<p style="text-align: justify;"> |
| 715 |
|
|
|
| 716 |
|
|
The above doses are for single administration. If necessary, repeat after 3, but not more than 4 days. |
| 717 |
|
|
|
| 718 |
|
|
</p> |
| 719 |
|
|
</div> |
| 720 |
|
|
|
| 721 |
|
|
|
| 722 |
|
|
|
| 723 |
|
|
|
| 724 |
|
|
|
| 725 |
|
|
|
| 726 |
|
|
|
| 727 |
|
|
|
| 728 |
|
|
|
| 729 |
|
|
|
| 730 |
|
|
|
| 731 |
|
|
|
| 732 |
|
|
<div align="justify"> |
| 733 |
|
|
<p style="text-align: justify;"> |
| 734 |
|
|
|
| 735 |
|
|
|
| 736 |
|
|
|
| 737 |
|
|
</p> |
| 738 |
|
|
</div> |
| 739 |
|
|
|
| 740 |
|
|
|
| 741 |
|
|
|
| 742 |
|
|
|
| 743 |
|
|
|
| 744 |
|
|
|
| 745 |
|
|
|
| 746 |
|
|
|
| 747 |
|
|
<table width="82.36%" border="1" cols="3" rows="6"> |
| 748 |
|
|
<tr> |
| 749 |
|
|
<td bgcolor="White" width="54.19%" rowspan="1" colspan="1"> |
| 750 |
|
|
|
| 751 |
|
|
<div align="left"> |
| 752 |
|
|
<p style="text-align: left;"> |
| 753 |
|
|
|
| 754 |
|
|
Species |
| 755 |
|
|
|
| 756 |
|
|
</p> |
| 757 |
|
|
</div> |
| 758 |
|
|
|
| 759 |
|
|
|
| 760 |
|
|
|
| 761 |
|
|
|
| 762 |
|
|
</td> |
| 763 |
|
|
|
| 764 |
|
|
|
| 765 |
|
|
|
| 766 |
|
|
|
| 767 |
|
|
|
| 768 |
|
|
<td bgcolor="White" width="25.90%" rowspan="1" colspan="1"> |
| 769 |
|
|
|
| 770 |
|
|
<div align="left"> |
| 771 |
|
|
<p style="text-align: left;"> |
| 772 |
|
|
|
| 773 |
|
|
Body weight |
| 774 |
|
|
|
| 775 |
|
|
</p> |
| 776 |
|
|
</div> |
| 777 |
|
|
|
| 778 |
|
|
|
| 779 |
|
|
|
| 780 |
|
|
|
| 781 |
|
|
</td> |
| 782 |
|
|
|
| 783 |
|
|
|
| 784 |
|
|
|
| 785 |
|
|
|
| 786 |
|
|
|
| 787 |
|
|
<td bgcolor="White" width="19.91%" rowspan="1" colspan="1"> |
| 788 |
|
|
|
| 789 |
|
|
<div align="left"> |
| 790 |
|
|
<p style="text-align: left;"> |
| 791 |
|
|
|
| 792 |
|
|
Dose |
| 793 |
|
|
|
| 794 |
|
|
</p> |
| 795 |
|
|
</div> |
| 796 |
|
|
|
| 797 |
|
|
|
| 798 |
|
|
|
| 799 |
|
|
|
| 800 |
|
|
</td> |
| 801 |
|
|
|
| 802 |
|
|
|
| 803 |
|
|
|
| 804 |
|
|
|
| 805 |
|
|
|
| 806 |
|
|
|
| 807 |
|
|
|
| 808 |
|
|
</tr> |
| 809 |
|
|
|
| 810 |
|
|
|
| 811 |
|
|
|
| 812 |
|
|
<tr> |
| 813 |
|
|
<td bgcolor="White" width="54.19%" rowspan="1" colspan="1"> |
| 814 |
|
|
|
| 815 |
|
|
<div align="left"> |
| 816 |
|
|
<p style="text-align: left;"> |
| 817 |
|
|
|
| 818 |
|
|
Horses |
| 819 |
|
|
|
| 820 |
|
|
</p> |
| 821 |
|
|
</div> |
| 822 |
|
|
|
| 823 |
|
|
|
| 824 |
|
|
|
| 825 |
|
|
|
| 826 |
|
|
</td> |
| 827 |
|
|
|
| 828 |
|
|
|
| 829 |
|
|
|
| 830 |
|
|
|
| 831 |
|
|
|
| 832 |
|
|
<td bgcolor="White" width="25.90%" rowspan="1" colspan="1"> |
| 833 |
|
|
|
| 834 |
|
|
<div align="left"> |
| 835 |
|
|
<p style="text-align: left;"> |
| 836 |
|
|
|
| 837 |
|
|
500 kg |
| 838 |
|
|
|
| 839 |
|
|
</p> |
| 840 |
|
|
</div> |
| 841 |
|
|
|
| 842 |
|
|
|
| 843 |
|
|
|
| 844 |
|
|
|
| 845 |
|
|
</td> |
| 846 |
|
|
|
| 847 |
|
|
|
| 848 |
|
|
|
| 849 |
|
|
|
| 850 |
|
|
|
| 851 |
|
|
<td bgcolor="White" width="19.91%" rowspan="1" colspan="1"> |
| 852 |
|
|
|
| 853 |
|
|
<div align="left"> |
| 854 |
|
|
<p style="text-align: left;"> |
| 855 |
|
|
|
| 856 |
|
|
20 mL |
| 857 |
|
|
|
| 858 |
|
|
</p> |
| 859 |
|
|
</div> |
| 860 |
|
|
|
| 861 |
|
|
|
| 862 |
|
|
|
| 863 |
|
|
|
| 864 |
|
|
</td> |
| 865 |
|
|
|
| 866 |
|
|
|
| 867 |
|
|
|
| 868 |
|
|
|
| 869 |
|
|
|
| 870 |
|
|
|
| 871 |
|
|
|
| 872 |
|
|
</tr> |
| 873 |
|
|
|
| 874 |
|
|
|
| 875 |
|
|
|
| 876 |
|
|
<tr> |
| 877 |
|
|
<td bgcolor="White" width="54.19%" rowspan="1" colspan="1"> |
| 878 |
|
|
|
| 879 |
|
|
<div align="left"> |
| 880 |
|
|
<p style="text-align: left;"> |
| 881 |
|
|
|
| 882 |
|
|
Cattle |
| 883 |
|
|
|
| 884 |
|
|
</p> |
| 885 |
|
|
</div> |
| 886 |
|
|
|
| 887 |
|
|
|
| 888 |
|
|
|
| 889 |
|
|
|
| 890 |
|
|
</td> |
| 891 |
|
|
|
| 892 |
|
|
|
| 893 |
|
|
|
| 894 |
|
|
|
| 895 |
|
|
|
| 896 |
|
|
<td bgcolor="White" width="25.90%" rowspan="1" colspan="1"> |
| 897 |
|
|
|
| 898 |
|
|
<div align="left"> |
| 899 |
|
|
<p style="text-align: left;"> |
| 900 |
|
|
|
| 901 |
|
|
400 kg |
| 902 |
|
|
|
| 903 |
|
|
</p> |
| 904 |
|
|
</div> |
| 905 |
|
|
|
| 906 |
|
|
|
| 907 |
|
|
|
| 908 |
|
|
|
| 909 |
|
|
</td> |
| 910 |
|
|
|
| 911 |
|
|
|
| 912 |
|
|
|
| 913 |
|
|
|
| 914 |
|
|
|
| 915 |
|
|
<td bgcolor="White" width="19.91%" rowspan="1" colspan="1"> |
| 916 |
|
|
|
| 917 |
|
|
<div align="left"> |
| 918 |
|
|
<p style="text-align: left;"> |
| 919 |
|
|
|
| 920 |
|
|
16 mL |
| 921 |
|
|
|
| 922 |
|
|
</p> |
| 923 |
|
|
</div> |
| 924 |
|
|
|
| 925 |
|
|
|
| 926 |
|
|
|
| 927 |
|
|
|
| 928 |
|
|
</td> |
| 929 |
|
|
|
| 930 |
|
|
|
| 931 |
|
|
|
| 932 |
|
|
|
| 933 |
|
|
|
| 934 |
|
|
|
| 935 |
|
|
|
| 936 |
|
|
</tr> |
| 937 |
|
|
|
| 938 |
|
|
|
| 939 |
|
|
|
| 940 |
|
|
<tr> |
| 941 |
|
|
<td bgcolor="White" width="54.19%" rowspan="1" colspan="1"> |
| 942 |
|
|
|
| 943 |
|
|
<div align="left"> |
| 944 |
|
|
<p style="text-align: left;"> |
| 945 |
|
|
|
| 946 |
|
|
Calves, sheep, swine |
| 947 |
|
|
|
| 948 |
|
|
</p> |
| 949 |
|
|
</div> |
| 950 |
|
|
|
| 951 |
|
|
|
| 952 |
|
|
|
| 953 |
|
|
|
| 954 |
|
|
</td> |
| 955 |
|
|
|
| 956 |
|
|
|
| 957 |
|
|
|
| 958 |
|
|
|
| 959 |
|
|
|
| 960 |
|
|
<td bgcolor="White" width="25.90%" rowspan="1" colspan="1"> |
| 961 |
|
|
|
| 962 |
|
|
<div align="left"> |
| 963 |
|
|
<p style="text-align: left;"> |
| 964 |
|
|
|
| 965 |
|
|
50 kg |
| 966 |
|
|
|
| 967 |
|
|
</p> |
| 968 |
|
|
</div> |
| 969 |
|
|
|
| 970 |
|
|
|
| 971 |
|
|
|
| 972 |
|
|
|
| 973 |
|
|
</td> |
| 974 |
|
|
|
| 975 |
|
|
|
| 976 |
|
|
|
| 977 |
|
|
|
| 978 |
|
|
|
| 979 |
|
|
<td bgcolor="White" width="19.91%" rowspan="1" colspan="1"> |
| 980 |
|
|
|
| 981 |
|
|
<div align="left"> |
| 982 |
|
|
<p style="text-align: left;"> |
| 983 |
|
|
|
| 984 |
|
|
2 mL |
| 985 |
|
|
|
| 986 |
|
|
</p> |
| 987 |
|
|
</div> |
| 988 |
|
|
|
| 989 |
|
|
|
| 990 |
|
|
|
| 991 |
|
|
|
| 992 |
|
|
</td> |
| 993 |
|
|
|
| 994 |
|
|
|
| 995 |
|
|
|
| 996 |
|
|
|
| 997 |
|
|
|
| 998 |
|
|
|
| 999 |
|
|
|
| 1000 |
|
|
</tr> |
| 1001 |
|
|
|
| 1002 |
|
|
|
| 1003 |
|
|
|
| 1004 |
|
|
<tr> |
| 1005 |
|
|
<td bgcolor="White" width="54.19%" rowspan="1" colspan="1"> |
| 1006 |
|
|
|
| 1007 |
|
|
<div align="left"> |
| 1008 |
|
|
<p style="text-align: left;"> |
| 1009 |
|
|
|
| 1010 |
|
|
Dogs |
| 1011 |
|
|
|
| 1012 |
|
|
</p> |
| 1013 |
|
|
</div> |
| 1014 |
|
|
|
| 1015 |
|
|
|
| 1016 |
|
|
|
| 1017 |
|
|
|
| 1018 |
|
|
</td> |
| 1019 |
|
|
|
| 1020 |
|
|
|
| 1021 |
|
|
|
| 1022 |
|
|
|
| 1023 |
|
|
|
| 1024 |
|
|
<td bgcolor="White" width="25.90%" rowspan="1" colspan="1"> |
| 1025 |
|
|
|
| 1026 |
|
|
<div align="left"> |
| 1027 |
|
|
<p style="text-align: left;"> |
| 1028 |
|
|
|
| 1029 |
|
|
10 kg |
| 1030 |
|
|
|
| 1031 |
|
|
</p> |
| 1032 |
|
|
</div> |
| 1033 |
|
|
|
| 1034 |
|
|
|
| 1035 |
|
|
|
| 1036 |
|
|
|
| 1037 |
|
|
</td> |
| 1038 |
|
|
|
| 1039 |
|
|
|
| 1040 |
|
|
|
| 1041 |
|
|
|
| 1042 |
|
|
|
| 1043 |
|
|
<td bgcolor="White" width="19.91%" rowspan="1" colspan="1"> |
| 1044 |
|
|
|
| 1045 |
|
|
<div align="left"> |
| 1046 |
|
|
<p style="text-align: left;"> |
| 1047 |
|
|
|
| 1048 |
|
|
1 mL |
| 1049 |
|
|
|
| 1050 |
|
|
</p> |
| 1051 |
|
|
</div> |
| 1052 |
|
|
|
| 1053 |
|
|
|
| 1054 |
|
|
|
| 1055 |
|
|
|
| 1056 |
|
|
</td> |
| 1057 |
|
|
|
| 1058 |
|
|
|
| 1059 |
|
|
|
| 1060 |
|
|
|
| 1061 |
|
|
|
| 1062 |
|
|
|
| 1063 |
|
|
|
| 1064 |
|
|
</tr> |
| 1065 |
|
|
|
| 1066 |
|
|
|
| 1067 |
|
|
|
| 1068 |
|
|
<tr> |
| 1069 |
|
|
<td bgcolor="White" width="54.19%" rowspan="1" colspan="1"> |
| 1070 |
|
|
|
| 1071 |
|
|
<div align="left"> |
| 1072 |
|
|
<p style="text-align: left;"> |
| 1073 |
|
|
|
| 1074 |
|
|
Cats |
| 1075 |
|
|
|
| 1076 |
|
|
</p> |
| 1077 |
|
|
</div> |
| 1078 |
|
|
|
| 1079 |
|
|
|
| 1080 |
|
|
|
| 1081 |
|
|
|
| 1082 |
|
|
</td> |
| 1083 |
|
|
|
| 1084 |
|
|
|
| 1085 |
|
|
|
| 1086 |
|
|
|
| 1087 |
|
|
|
| 1088 |
|
|
<td bgcolor="White" width="25.90%" rowspan="1" colspan="1"> |
| 1089 |
|
|
|
| 1090 |
|
|
<div align="left"> |
| 1091 |
|
|
<p style="text-align: left;"> |
| 1092 |
|
|
|
| 1093 |
|
|
5 kg |
| 1094 |
|
|
|
| 1095 |
|
|
</p> |
| 1096 |
|
|
</div> |
| 1097 |
|
|
|
| 1098 |
|
|
|
| 1099 |
|
|
|
| 1100 |
|
|
|
| 1101 |
|
|
</td> |
| 1102 |
|
|
|
| 1103 |
|
|
|
| 1104 |
|
|
|
| 1105 |
|
|
|
| 1106 |
|
|
|
| 1107 |
|
|
<td bgcolor="White" width="19.91%" rowspan="1" colspan="1"> |
| 1108 |
|
|
|
| 1109 |
|
|
<div align="left"> |
| 1110 |
|
|
<p style="text-align: left;"> |
| 1111 |
|
|
|
| 1112 |
|
|
0.5 mL |
| 1113 |
|
|
|
| 1114 |
|
|
</p> |
| 1115 |
|
|
</div> |
| 1116 |
|
|
|
| 1117 |
|
|
|
| 1118 |
|
|
|
| 1119 |
|
|
|
| 1120 |
|
|
</td> |
| 1121 |
|
|
|
| 1122 |
|
|
|
| 1123 |
|
|
|
| 1124 |
|
|
|
| 1125 |
|
|
|
| 1126 |
|
|
|
| 1127 |
|
|
|
| 1128 |
|
|
</tr> |
| 1129 |
|
|
|
| 1130 |
|
|
</table> |
| 1131 |
|
|
|
| 1132 |
|
|
|
| 1133 |
|
|
|
| 1134 |
|
|
|
| 1135 |
|
|
<div align="justify"> |
| 1136 |
|
|
<p style="text-align: justify;"> |
| 1137 |
|
|
|
| 1138 |
|
|
|
| 1139 |
|
|
|
| 1140 |
|
|
</p> |
| 1141 |
|
|
</div> |
| 1142 |
|
|
|
| 1143 |
|
|
|
| 1144 |
|
|
|
| 1145 |
|
|
|
| 1146 |
|
|
|
| 1147 |
|
|
|
| 1148 |
|
|
|
| 1149 |
|
|
|
| 1150 |
|
|
|
| 1151 |
|
|
|
| 1152 |
|
|
|
| 1153 |
|
|
|
| 1154 |
|
|
<div align="justify"> |
| 1155 |
|
|
<p style="text-align: justify;"> |
| 1156 |
|
|
|
| 1157 |
|
|
<b><i>Side effects</i></b><b></b> |
| 1158 |
|
|
|
| 1159 |
|
|
</p> |
| 1160 |
|
|
</div> |
| 1161 |
|
|
|
| 1162 |
|
|
|
| 1163 |
|
|
|
| 1164 |
|
|
|
| 1165 |
|
|
|
| 1166 |
|
|
|
| 1167 |
|
|
|
| 1168 |
|
|
|
| 1169 |
|
|
|
| 1170 |
|
|
|
| 1171 |
|
|
|
| 1172 |
|
|
|
| 1173 |
|
|
<div align="justify"> |
| 1174 |
|
|
<p style="text-align: justify;"> |
| 1175 |
|
|
|
| 1176 |
|
|
Penicillin injection suspensions that combine procaine benzylpenicillin and benzathine benzylpenicillin produce side effects on extremely rare occasions. |
| 1177 |
|
|
|
| 1178 |
|
|
</p> |
| 1179 |
|
|
</div> |
| 1180 |
|
|
|
| 1181 |
|
|
|
| 1182 |
|
|
|
| 1183 |
|
|
|
| 1184 |
|
|
|
| 1185 |
|
|
|
| 1186 |
|
|
|
| 1187 |
|
|
|
| 1188 |
|
|
|
| 1189 |
|
|
|
| 1190 |
|
|
|
| 1191 |
|
|
|
| 1192 |
|
|
<div align="justify"> |
| 1193 |
|
|
<p style="text-align: justify;"> |
| 1194 |
|
|
|
| 1195 |
|
|
|
| 1196 |
|
|
|
| 1197 |
|
|
</p> |
| 1198 |
|
|
</div> |
| 1199 |
|
|
|
| 1200 |
|
|
|
| 1201 |
|
|
|
| 1202 |
|
|
|
| 1203 |
|
|
|
| 1204 |
|
|
|
| 1205 |
|
|
|
| 1206 |
|
|
|
| 1207 |
|
|
|
| 1208 |
|
|
|
| 1209 |
|
|
|
| 1210 |
|
|
|
| 1211 |
|
|
<div align="justify"> |
| 1212 |
|
|
<p style="text-align: justify;"> |
| 1213 |
|
|
|
| 1214 |
|
|
<b><i>Warnings and precautions</i></b><b></b> |
| 1215 |
|
|
|
| 1216 |
|
|
</p> |
| 1217 |
|
|
</div> |
| 1218 |
|
|
|
| 1219 |
|
|
|
| 1220 |
|
|
|
| 1221 |
|
|
|
| 1222 |
|
|
|
| 1223 |
|
|
|
| 1224 |
|
|
|
| 1225 |
|
|
|
| 1226 |
|
|
|
| 1227 |
|
|
|
| 1228 |
|
|
|
| 1229 |
|
|
|
| 1230 |
|
|
<div align="justify"> |
| 1231 |
|
|
<p style="text-align: justify;"> |
| 1232 |
|
|
|
| 1233 |
|
|
To avoid local tissue irritation, the dose injected to large animals should not exceed 20 mL. |
| 1234 |
|
|
|
| 1235 |
|
|
</p> |
| 1236 |
|
|
</div> |
| 1237 |
|
|
|
| 1238 |
|
|
|
| 1239 |
|
|
|
| 1240 |
|
|
|
| 1241 |
|
|
|
| 1242 |
|
|
|
| 1243 |
|
|
|
| 1244 |
|
|
|
| 1245 |
|
|
|
| 1246 |
|
|
|
| 1247 |
|
|
|
| 1248 |
|
|
|
| 1249 |
|
|
<div align="justify"> |
| 1250 |
|
|
<p style="text-align: justify;"> |
| 1251 |
|
|
|
| 1252 |
|
|
|
| 1253 |
|
|
|
| 1254 |
|
|
</p> |
| 1255 |
|
|
</div> |
| 1256 |
|
|
|
| 1257 |
|
|
|
| 1258 |
|
|
|
| 1259 |
|
|
|
| 1260 |
|
|
|
| 1261 |
|
|
|
| 1262 |
|
|
|
| 1263 |
|
|
|
| 1264 |
|
|
|
| 1265 |
|
|
|
| 1266 |
|
|
|
| 1267 |
|
|
|
| 1268 |
|
|
<div align="justify"> |
| 1269 |
|
|
<p style="text-align: justify;"> |
| 1270 |
|
|
|
| 1271 |
|
|
Benzylpenicillin preparations are not active against beta-lactamase producing organisms. |
| 1272 |
|
|
|
| 1273 |
|
|
</p> |
| 1274 |
|
|
</div> |
| 1275 |
|
|
|
| 1276 |
|
|
|
| 1277 |
|
|
|
| 1278 |
|
|
|
| 1279 |
|
|
|
| 1280 |
|
|
|
| 1281 |
|
|
|
| 1282 |
|
|
|
| 1283 |
|
|
|
| 1284 |
|
|
|
| 1285 |
|
|
|
| 1286 |
|
|
|
| 1287 |
|
|
<div align="justify"> |
| 1288 |
|
|
<p style="text-align: justify;"> |
| 1289 |
|
|
|
| 1290 |
|
|
|
| 1291 |
|
|
|
| 1292 |
|
|
</p> |
| 1293 |
|
|
</div> |
| 1294 |
|
|
|
| 1295 |
|
|
|
| 1296 |
|
|
|
| 1297 |
|
|
|
| 1298 |
|
|
|
| 1299 |
|
|
|
| 1300 |
|
|
|
| 1301 |
|
|
|
| 1302 |
|
|
|
| 1303 |
|
|
|
| 1304 |
|
|
|
| 1305 |
|
|
|
| 1306 |
|
|
<div align="justify"> |
| 1307 |
|
|
<p style="text-align: justify;"> |
| 1308 |
|
|
|
| 1309 |
|
|
Concurrent administration of tetracycline and/or macrolide antibiotics with penicillin may diminish antimicrobial action of penicillin. |
| 1310 |
|
|
|
| 1311 |
|
|
</p> |
| 1312 |
|
|
</div> |
| 1313 |
|
|
|
| 1314 |
|
|
|
| 1315 |
|
|
|
| 1316 |
|
|
|
| 1317 |
|
|
|
| 1318 |
|
|
|
| 1319 |
|
|
|
| 1320 |
|
|
|
| 1321 |
|
|
|
| 1322 |
|
|
|
| 1323 |
|
|
|
| 1324 |
|
|
|
| 1325 |
|
|
<div align="justify"> |
| 1326 |
|
|
<p style="text-align: justify;"> |
| 1327 |
|
|
|
| 1328 |
|
|
|
| 1329 |
|
|
|
| 1330 |
|
|
</p> |
| 1331 |
|
|
</div> |
| 1332 |
|
|
|
| 1333 |
|
|
|
| 1334 |
|
|
|
| 1335 |
|
|
|
| 1336 |
|
|
|
| 1337 |
|
|
|
| 1338 |
|
|
|
| 1339 |
|
|
|
| 1340 |
|
|
|
| 1341 |
|
|
|
| 1342 |
|
|
|
| 1343 |
|
|
|
| 1344 |
|
|
<div align="justify"> |
| 1345 |
|
|
<p style="text-align: justify;"> |
| 1346 |
|
|
|
| 1347 |
|
|
In case of allergic reactions (skin changes, urticaria, anaphylactic shock, etc.) institute appropriate treatment (adrenaline, glucocorticoids, antihistaminics). |
| 1348 |
|
|
|
| 1349 |
|
|
</p> |
| 1350 |
|
|
</div> |
| 1351 |
|
|
|
| 1352 |
|
|
|
| 1353 |
|
|
|
| 1354 |
|
|
|
| 1355 |
|
|
|
| 1356 |
|
|
|
| 1357 |
|
|
|
| 1358 |
|
|
|
| 1359 |
|
|
|
| 1360 |
|
|
|
| 1361 |
|
|
|
| 1362 |
|
|
|
| 1363 |
|
|
<div align="justify"> |
| 1364 |
|
|
<p style="text-align: justify;"> |
| 1365 |
|
|
|
| 1366 |
|
|
|
| 1367 |
|
|
|
| 1368 |
|
|
</p> |
| 1369 |
|
|
</div> |
| 1370 |
|
|
|
| 1371 |
|
|
|
| 1372 |
|
|
|
| 1373 |
|
|
|
| 1374 |
|
|
|
| 1375 |
|
|
|
| 1376 |
|
|
|
| 1377 |
|
|
|
| 1378 |
|
|
|
| 1379 |
|
|
|
| 1380 |
|
|
|
| 1381 |
|
|
|
| 1382 |
|
|
<div align="justify"> |
| 1383 |
|
|
<p style="text-align: justify;"> |
| 1384 |
|
|
|
| 1385 |
|
|
<b><i>Withdrawal</i></b> |
| 1386 |
|
|
|
| 1387 |
|
|
</p> |
| 1388 |
|
|
</div> |
| 1389 |
|
|
|
| 1390 |
|
|
|
| 1391 |
|
|
|
| 1392 |
|
|
|
| 1393 |
|
|
|
| 1394 |
|
|
|
| 1395 |
|
|
|
| 1396 |
|
|
|
| 1397 |
|
|
|
| 1398 |
|
|
|
| 1399 |
|
|
|
| 1400 |
|
|
|
| 1401 |
|
|
<div align="justify"> |
| 1402 |
|
|
<p style="text-align: justify;"> |
| 1403 |
|
|
|
| 1404 |
|
|
Meat, organs and other edible tissues 21 days |
| 1405 |
|
|
|
| 1406 |
|
|
</p> |
| 1407 |
|
|
</div> |
| 1408 |
|
|
|
| 1409 |
|
|
|
| 1410 |
|
|
|
| 1411 |
|
|
|
| 1412 |
|
|
|
| 1413 |
|
|
|
| 1414 |
|
|
|
| 1415 |
|
|
|
| 1416 |
|
|
|
| 1417 |
|
|
|
| 1418 |
|
|
|
| 1419 |
|
|
|
| 1420 |
|
|
<div align="justify"> |
| 1421 |
|
|
<p style="text-align: justify;"> |
| 1422 |
|
|
|
| 1423 |
|
|
Milk 10 days |
| 1424 |
|
|
|
| 1425 |
|
|
</p> |
| 1426 |
|
|
</div> |
| 1427 |
|
|
|
| 1428 |
|
|
|
| 1429 |
|
|
|
| 1430 |
|
|
|
| 1431 |
|
|
|
| 1432 |
|
|
|
| 1433 |
|
|
|
| 1434 |
|
|
|
| 1435 |
|
|
|
| 1436 |
|
|
|
| 1437 |
|
|
|
| 1438 |
|
|
|
| 1439 |
|
|
<div align="justify"> |
| 1440 |
|
|
<p style="text-align: justify;"> |
| 1441 |
|
|
|
| 1442 |
|
|
|
| 1443 |
|
|
|
| 1444 |
|
|
</p> |
| 1445 |
|
|
</div> |
| 1446 |
|
|
|
| 1447 |
|
|
|
| 1448 |
|
|
|
| 1449 |
|
|
|
| 1450 |
|
|
|
| 1451 |
|
|
|
| 1452 |
|
|
|
| 1453 |
|
|
|
| 1454 |
|
|
|
| 1455 |
|
|
|
| 1456 |
|
|
|
| 1457 |
|
|
|
| 1458 |
|
|
<div align="justify"> |
| 1459 |
|
|
<p style="text-align: justify;"> |
| 1460 |
|
|
|
| 1461 |
|
|
<b><i>Storage</i></b><b> </b> |
| 1462 |
|
|
|
| 1463 |
|
|
</p> |
| 1464 |
|
|
</div> |
| 1465 |
|
|
|
| 1466 |
|
|
|
| 1467 |
|
|
|
| 1468 |
|
|
|
| 1469 |
|
|
|
| 1470 |
|
|
|
| 1471 |
|
|
|
| 1472 |
|
|
|
| 1473 |
|
|
|
| 1474 |
|
|
|
| 1475 |
|
|
|
| 1476 |
|
|
|
| 1477 |
|
|
<div align="justify"> |
| 1478 |
|
|
<p style="text-align: justify;"> |
| 1479 |
|
|
|
| 1480 |
|
|
Store in a cool and dark place, up to 158C. Keep away from children. Avoid freezing. |
| 1481 |
|
|
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| 1482 |
|
|
</p> |
| 1483 |
|
|
</div> |
| 1484 |
|
|
|
| 1485 |
|
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| 1486 |
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| 1487 |
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| 1488 |
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| 1489 |
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| 1490 |
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| 1491 |
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| 1492 |
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| 1493 |
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| 1494 |
|
|
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| 1495 |
|
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| 1496 |
|
|
<div align="justify"> |
| 1497 |
|
|
<p style="text-align: justify;"> |
| 1498 |
|
|
|
| 1499 |
|
|
|
| 1500 |
|
|
|
| 1501 |
|
|
</p> |
| 1502 |
|
|
</div> |
| 1503 |
|
|
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| 1504 |
|
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| 1505 |
|
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| 1506 |
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| 1507 |
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| 1508 |
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| 1509 |
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| 1510 |
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| 1511 |
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| 1512 |
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| 1513 |
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| 1514 |
|
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| 1515 |
|
|
<div align="justify"> |
| 1516 |
|
|
<p style="text-align: justify;"> |
| 1517 |
|
|
|
| 1518 |
|
|
<b><i>Shelf life</i></b><b></b> |
| 1519 |
|
|
|
| 1520 |
|
|
</p> |
| 1521 |
|
|
</div> |
| 1522 |
|
|
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| 1523 |
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| 1524 |
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| 1525 |
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| 1526 |
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| 1527 |
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| 1528 |
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| 1529 |
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| 1530 |
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| 1531 |
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| 1532 |
|
|
|
| 1533 |
|
|
|
| 1534 |
|
|
<div align="justify"> |
| 1535 |
|
|
<p style="text-align: justify;"> |
| 1536 |
|
|
|
| 1537 |
|
|
Denoted on the packaging (2 years in the original pack). |
| 1538 |
|
|
|
| 1539 |
|
|
</p> |
| 1540 |
|
|
</div> |
| 1541 |
|
|
|
| 1542 |
|
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| 1543 |
|
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| 1544 |
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| 1545 |
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| 1546 |
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| 1547 |
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| 1548 |
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| 1549 |
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| 1550 |
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| 1551 |
|
|
|
| 1552 |
|
|
|
| 1553 |
|
|
<div align="justify"> |
| 1554 |
|
|
<p style="text-align: justify;"> |
| 1555 |
|
|
|
| 1556 |
|
|
|
| 1557 |
|
|
|
| 1558 |
|
|
</p> |
| 1559 |
|
|
</div> |
| 1560 |
|
|
|
| 1561 |
|
|
|
| 1562 |
|
|
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| 1563 |
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| 1564 |
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| 1565 |
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| 1566 |
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| 1567 |
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| 1568 |
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| 1569 |
|
|
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| 1570 |
|
|
|
| 1571 |
|
|
|
| 1572 |
|
|
<div align="justify"> |
| 1573 |
|
|
<p style="text-align: justify;"> |
| 1574 |
|
|
|
| 1575 |
|
|
<b><i>Legal category</i></b><b></b> |
| 1576 |
|
|
|
| 1577 |
|
|
</p> |
| 1578 |
|
|
</div> |
| 1579 |
|
|
|
| 1580 |
|
|
|
| 1581 |
|
|
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| 1582 |
|
|
|
| 1583 |
|
|
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| 1584 |
|
|
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| 1585 |
|
|
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| 1586 |
|
|
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| 1587 |
|
|
|
| 1588 |
|
|
|
| 1589 |
|
|
|
| 1590 |
|
|
|
| 1591 |
|
|
<div align="justify"> |
| 1592 |
|
|
<p style="text-align: justify;"> |
| 1593 |
|
|
|
| 1594 |
|
|
On prescription only. |
| 1595 |
|
|
|
| 1596 |
|
|
</p> |
| 1597 |
|
|
</div> |
| 1598 |
|
|
|
| 1599 |
|
|
|
| 1600 |
|
|
|
| 1601 |
|
|
|
| 1602 |
|
|
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| 1603 |
|
|
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| 1604 |
|
|
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| 1605 |
|
|
|
| 1606 |
|
|
|
| 1607 |
|
|
|
| 1608 |
|
|
|
| 1609 |
|
|
|
| 1610 |
|
|
<div align="justify"> |
| 1611 |
|
|
<p style="text-align: justify;"> |
| 1612 |
|
|
|
| 1613 |
|
|
<b><i></i></b> |
| 1614 |
|
|
|
| 1615 |
|
|
</p> |
| 1616 |
|
|
</div> |
| 1617 |
|
|
|
| 1618 |
|
|
|
| 1619 |
|
|
|
| 1620 |
|
|
|
| 1621 |
|
|
|
| 1622 |
|
|
|
| 1623 |
|
|
|
| 1624 |
|
|
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| 1625 |
|
|
|
| 1626 |
|
|
|
| 1627 |
|
|
|
| 1628 |
|
|
|
| 1629 |
|
|
<div align="justify"> |
| 1630 |
|
|
<p style="text-align: justify;"> |
| 1631 |
|
|
|
| 1632 |
|
|
Supply<b></b> |
| 1633 |
|
|
|
| 1634 |
|
|
</p> |
| 1635 |
|
|
</div> |
| 1636 |
|
|
|
| 1637 |
|
|
|
| 1638 |
|
|
|
| 1639 |
|
|
|
| 1640 |
|
|
|
| 1641 |
|
|
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| 1642 |
|
|
|
| 1643 |
|
|
|
| 1644 |
|
|
|
| 1645 |
|
|
|
| 1646 |
|
|
|
| 1647 |
|
|
|
| 1648 |
|
|
<div align="justify"> |
| 1649 |
|
|
<p style="text-align: justify;"> |
| 1650 |
|
|
|
| 1651 |
|
|
Bottles with 50 mL and 100 mL. |
| 1652 |
|
|
|
| 1653 |
|
|
</p> |
| 1654 |
|
|
</div> |
| 1655 |
|
|
|
| 1656 |
|
|
|
| 1657 |
|
|
|
| 1658 |
|
|
|
| 1659 |
|
|
|
| 1660 |
|
|
|
| 1661 |
|
|
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| 1662 |
|
|
|
| 1663 |
|
|
|
| 1664 |
|
|
|
| 1665 |
|
|
|
| 1666 |
|
|
|
| 1667 |
|
|
<div align="justify"> |
| 1668 |
|
|
<p style="text-align: justify;"> |
| 1669 |
|
|
|
| 1670 |
|
|
|
| 1671 |
|
|
|
| 1672 |
|
|
</p> |
| 1673 |
|
|
</div> |
| 1674 |
|
|
|
| 1675 |
|
|
|
| 1676 |
|
|
|
| 1677 |
|
|
|
| 1678 |
|
|
|
| 1679 |
|
|
|
| 1680 |
|
|
|
| 1681 |
|
|
|
| 1682 |
|
|
|
| 1683 |
|
|
|
| 1684 |
|
|
|
| 1685 |
|
|
|
| 1686 |
|
|
<div align="justify"> |
| 1687 |
|
|
<p style="text-align: justify;"> |
| 1688 |
|
|
|
| 1689 |
|
|
<b><i>Manufacturer</i></b><b></b> |
| 1690 |
|
|
|
| 1691 |
|
|
</p> |
| 1692 |
|
|
</div> |
| 1693 |
|
|
|
| 1694 |
|
|
|
| 1695 |
|
|
|
| 1696 |
|
|
|
| 1697 |
|
|
|
| 1698 |
|
|
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| 1699 |
|
|
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| 1700 |
|
|
|
| 1701 |
|
|
|
| 1702 |
|
|
|
| 1703 |
|
|
|
| 1704 |
|
|
|
| 1705 |
|
|
<div align="justify"> |
| 1706 |
|
|
<p style="text-align: justify;"> |
| 1707 |
|
|
|
| 1708 |
|
|
VETERINA Animal Health Ltd., Croatia |
| 1709 |
|
|
|
| 1710 |
|
|
</p> |
| 1711 |
|
|
</div> |
| 1712 |
|
|
|
| 1713 |
|
|
|
| 1714 |
|
|
|
| 1715 |
|
|
|
| 1716 |
|
|
|
| 1717 |
|
|
|
| 1718 |
|
|
|
| 1719 |
|
|
|
| 1720 |
|
|
|
| 1721 |
|
|
|
| 1722 |
|
|
|
| 1723 |
|
|
|
| 1724 |
|
|
<div align="justify"> |
| 1725 |
|
|
<p style="text-align: justify;"> |
| 1726 |
|
|
|
| 1727 |
|
|
|
| 1728 |
|
|
|
| 1729 |
|
|
</p> |
| 1730 |
|
|
</div> |
| 1731 |
|
|
|
| 1732 |
|
|
|
| 1733 |
|
|
|
| 1734 |
|
|
|
| 1735 |
|
|
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| 1736 |
|
|
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| 1737 |
|
|
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| 1738 |
|
|
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| 1739 |
|
|
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| 1740 |
|
|
|
| 1741 |
|
|
|
| 1742 |
|
|
|
| 1743 |
|
|
<div align="left"> |
| 1744 |
|
|
<p style="text-align: left;"> |
| 1745 |
|
|
|
| 1746 |
|
|
|
| 1747 |
|
|
|
| 1748 |
|
|
</p> |
| 1749 |
|
|
</div> |
| 1750 |
|
|
|
| 1751 |
|
|
|
| 1752 |
|
|
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| 1753 |
|
|
|
| 1754 |
|
|
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| 1755 |
|
|
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| 1756 |
|
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|
| 1757 |
|
|
<!--Section Ends--> |
| 1758 |
|
|
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| 1759 |
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| 1760 |
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| 1761 |
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| 1762 |
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| 1763 |
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| 1764 |
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| 1765 |
|
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|
Parent Directory
| 
Revision Log