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8     <div align="Center"><b>State-of-the-art facility<br>
9     <br>
10     </b>
11     <div align="Left"><i>Zagreb, 12 December 2001</i><br>
12     <br>
13     <div align="Center">Croatian Prime Minister Ivica Racan opens PLIVA&#8217;s new
14     Oral Solid Dosage Forms facility<br>
15     </div>
16     </div>
17     <br>
18     </div>
19     With the press of a button, Croatian Prime Minister Ivica Racan launched
20     the automatically controlled vehicle, symbolically opening PLIVA&#8217;s new Oral
21     Solid Dosage Forms facility, one of the state-of-the-art facilities for the
22     production of oral solid drug forms in the world. Accompanying Prime Minister
23     Racan were Croatian Minister of Health Andro Vlahucic, representatives from
24     the Croatian Institute for Drug Control, the Croatian Institute for Health
25     Insurance (HZZO), Faculty of Medicine and Faculty of Pharmacy and Biochemistry,
26     whose hosts from PLIVA were CEO of PLIVA Zeljko Covic, members of PLIVA&#8217;s
27     Management Board and the Oral Solid Dosage Forms Facility Project Director
28     Zeljko Brebric. <br>
29     <br>
30     The total investment amounted approximately to HRK 640 million, which ranks
31     PLIVA among the largest investors in Croatian economy, and the entire project,
32     from the project beginning to full operation, lasted about three years.<br>
33     <br>
34     The plant was constructed in line with the highest international standards
35     and is one of the most modern facilities in the world. Highly sophisticated
36     equipment and level of automatization will significantly shorten the manufacturing
37     process, enable the production of a range of various products and reduce
38     production costs. The facility will manufacture more than 900 tons, or approximately
39     2 billion tablets, coated tablets and capsules.<br>
40     <br>
41     The basic features of the new facility are automated transport of bulk substances,
42     intermediaries and finished products as well as closed production areas completely
43     aligned with the most demanding sanitary requirements, production conditions
44     and personnel safety requirements. Seventy specially trained employees will
45     be working in the new Oral Solid Dosage Forms facility. &nbsp;<br>
46     <br>
47     Part of the investment is the completely automated high-reach warehouse for
48     starting material and intermediaries; a &#8220;pilot&#8221; plant where new drugs from
49     PLIVA&#8217;s Development can be effectively reproduced in larger - semiindustrial
50     amounts, at the same time ensuring the equal level of quality, enabling them
51     to enter industrial manufacturing as such. In addition, the drug packaging
52     plant has been completely renovated, new modern analytical laboratories have
53     been built as well as a management and administration center and measurement
54     and calibration center. <br>
55     <br>
56     The construction of PLIVA&#8217;s new facility lasted three years. The technological
57     project was designed in cooperation with the Belgian consultant ELVECO, facility
58     design and installation were performed by the Croatian company &#8220;Termoinzenjering&#8221;
59     and construction was carried out by &#8220;Tehnika&#8221;. The general contractor for
60     interior work and technical infrastructure was the Austrian company VATECH
61     Elin EBG, whose most important subcontractors were the Croatian companies
62     Ekomont, Enel, Termovod, Siemens-Landis&amp;Staefa, Enikon, Tehnomobil, Tehnika
63     and others. During the design and construction, PLIVA placed special attention
64     on environmental protection issues. Production has no affects on the environment,
65     and all waste resulting from production is treated according to the highest
66     international environmental standards.<br>
67     <br>
68     Commenting on the significance of this facility for PLIVA&#8217;s operations in
69     the future, PLIVA&#8217;s CEO Zeljko Covic stressed: &#8220;Owing to the fact that it
70     meets the highest standards of Good Manufacturing Practice, the most important
71     feature of this new facility is that it will enable the production of finished
72     drug forms to be exported to the demanding West European and US markets.
73     With the construction of the new Oral Solid Dosage Forms facility, PLIVA
74     has met the demands of the market that requires a wide range of high quality
75     pharmaceutical products, with the highest standards of safety at work, environmental
76     protection and energy management. This fulfills PLIVA&#8217;s vision &#8211; to be a
77     pharmaceutical company bringing superior and innovative solutions to customer
78     needs, by competing in the global market.&#8221;<br>
79     </body>
80     </html>

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