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<body> |
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<br> |
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<div align="Justify"> |
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<p style="text-align: justify; "> <b>TIAVET</b><b><sup> </sup></b><b> |
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20 %</b> </p> |
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<div align="Justify"> |
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<p style="text-align: justify; "> raztopina za injiciranje </p> |
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<div align="Justify"> |
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<p style="text-align: justify; "> Za uporabo v veterinarski medicini </p> |
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<div align="Justify"> |
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<p style="text-align: justify; "> </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> <b>Sestava</b> </p> |
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<div align="Justify"> |
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<p style="text-align: justify; "> 1 ml oljne raztopine vsebuje 200 mg tiamulin |
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hidrogenfumarata. </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> </p> |
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</div> |
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<p style="text-align: justify; "> <b>Delovanje</b> </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> Tiamulin je polsintetièni antibiotik |
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s širokim antimikrobnim spektrom. Pri obèutljivih mikroorganizmih |
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ovira sintezo beljakovin. Moèno deluje proti mikoplazmam (<i>Mycoplasma |
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hyopneumoniae, M. hyorhinis, M. hyosynoviae</i>) in enako tudi proti povzroèiteljem |
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krvave prašièje driske (<i>Se</i><i>rpulina hyodysenteriae</i>). Tiavet |
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20 % zavira rast in razmno¾evanje številnih po Gramu pozitivnih (<i> |
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Staphylococcus </i>spp.,<i> Streptococcus </i>spp.,<i> Clostridium perfringens, |
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Listeria monocitogenes, Erysipelothrix </i>spp.,<i> Corynebacterium pyogenes</i> |
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) in po Gramu negativnih bakterij (<i>Pasteurella </i>spp.,<i> Klebsiella |
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pneumoniae, Actinobacillus </i>spp.,<i> Fusobacterium necrophorum, Bacteroides |
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</i>spp.,<i> Campylobacter coli</i>) ter leptospir. </p> |
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</div> |
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<p style="text-align: justify; "> Tiavet 20 % ne deluje proti po Gramu negativnim |
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èrevesnim bakterijam. </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> Po intramuskularnem dajanju se tiamulin |
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hitro resorbira in najvišjo raven v krvi dose¾e v eni uri. Iz organizma |
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se izloèa predvsem z ¾olèem in seèem. </p> |
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</div> |
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<p style="text-align: justify; "> </p> |
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</div> |
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<p style="text-align: justify; "> <b>Indikacije</b> </p> |
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</div> |
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<p style="text-align: justify; "> Tiavet 20 % uporabljamo za zdravljenje |
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prašièjih bolezni: </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> - krvave prašièje driske (dizenterije), |
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povzroèene s <i>Serpulino hyodys</i><i>enteriae,</i> in </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> sekundarnih infekcij s <i>Bacteroidesom |
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spp.</i> in <i>Fusobacteriumom necrophorumom</i>; </p> |
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</div> |
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<p style="text-align: justify; "> - kompleksa enzootiène prašièje |
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pnevmonije, povzroèene s <i>M. hyopneumoniae</i>, ter </p> |
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</div> |
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<p style="text-align: justify; "> spremljajoèih infekcij, v katerih |
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sodelujejo <i>Pasteurella multocida, Staphylococcus</i> </p> |
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<div align="Justify"> |
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<p style="text-align: justify; "> <i> </i>in <i>Streptococcus spp., Bordetella |
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bronchiseptica, Corynebacterium pyogenes</i> ter </p> |
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</div> |
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<p style="text-align: justify; "> <i>Actinobacillus spp.</i>; </p> |
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<p style="text-align: justify; "> - mikoplazmatskega prašièjega artritisa, |
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povzroèenega z <i>M. hyosynoviae</i>. </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> Zdravljenje zmanjšuje šepavost in izboljšuje |
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prirast. </p> |
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<p style="text-align: justify; "> </p> |
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</div> |
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<p style="text-align: justify; "> <b>Kontraindikacije</b> </p> |
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</div> |
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<p style="text-align: justify; "> Ne smemo ga dajati prašièem, ki |
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s hrano soèasno dobivajo ionoforne antibiotike (npr. salinomicin, |
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monenzin, narazin ipd.). Ionofornih antibiotikov ne smemo dajati prašièem |
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niti 7 dni pred zdravljenjem s Tiavetom 20 % niti 7 dni po njem. Tiaveta |
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ne smemo dajati brejim plemenskim svinjam in mladicam v zgodnji stopnji |
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brejosti. </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> <b>Naèin dajanja in odmerki</b> |
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</p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> Tiavet 20 % dajemo intramuskularno v vrat |
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za bazo uhlja. </p> |
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</div> |
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<p style="text-align: justify; "> Za zdravljenje krvave prašièje |
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driske (dizenterije) damo klinièno bolnim prašièem injekcijo |
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z enkratnim odmerkom po 1 ml Tiaveta 20 % na 20 kg telesne mase (10 mg tiamulinovega |
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hidrogenfumarata na kg telesne mase). Pri hujših oblikah bolezni lahko damo |
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še eno injekcijo naslednjega dne. Zdravljenje klinièno zbolelih in |
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drugih prašièev v prizadeti reji je treba nadaljevati s peroralnim |
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dajanjem Tiaveta 2 % P, umešanega v hrano, v kolièini 5 kg praška |
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na 1 tono zmesi, 7 do 10 dni. </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> </p> |
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</div> |
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<p style="text-align: justify; "> </p> |
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</div> |
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<p style="text-align: justify; "> Za zdravljenje enzootiène (mikoplazmatske) |
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pnevmonije damo 1,5 do 2 ml Tiaveta 20 % na 20 kg telesne mase dnevno, 3 |
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dni zapored (15 do 20 mg tiamulinovega hidrogenfumarata na kg telesne mase). |
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Injekcije dajemo klinièno bolnim ¾ivalim; hkrati zdravimo tudi |
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vse ¾ivali v prizadeti reji, ki prejemajo v hrano |
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umešan Tiavet 2 % P v kolièini 1,5 kg praška na 1 tono zmesi, 3 do |
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6 tednov ali do konca reje. </p> |
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</div> |
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<p style="text-align: justify; "> Za zdravljenje mikoplazmatskega artritisa |
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dajemo 1 ml 20 - % injekcijske raztopine Tiavet na 10 kg telesne mase dnevno, |
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3 dni zapored (20 mg tiamulinovega hidrogenfumarata na kg telesne mase). |
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</p> |
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</div> |
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<p style="text-align: justify; "> </p> |
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</div> |
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<p style="text-align: justify; "> <b>Stranski uèinki</b> </p> |
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</div> |
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<p style="text-align: justify; "> Med zdravljenjem se zelo redko pojavi |
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ko¾ni eritem v predelu trebuha in spolnih organov. Tedaj je treba |
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dajanje Tiaveta 20 % ukiniti in ¾ivali umiti z vodo, da bi iz ko¾e |
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sprali ostanke iztrebkov in seèa. </p> |
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</div> |
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<p style="text-align: justify; "> </p> |
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<p style="text-align: justify; "> <b>Opozorilo in varnostni ukrepi</b> </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> Èe se po tridnevnem zdravljenju |
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stanje ¾ivali ne zboljša, lahko nadaljujemo z dajanjem Tiaveta le, |
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èe so rezultati antibiograma dokazali, da so izolirani povzroèitelji |
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obèutljivi za tiamulin. </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> Injekcije Tiaveta 20 % lokalno dra¾ijo, |
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zato pri veèkratnem dajanju svetujemo zamenjavo mesta vnosa. </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> Injekcijska raztopina Tiavet 20 % vsebuje |
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nosilec sezamovo olje, zato moramo pri odvzemu iz steklenièke uporabljati |
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popolnoma suho iglo in brizgo. </p> |
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</div> |
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<p style="text-align: justify; "> </p> |
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</div> |
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<p style="text-align: justify; "> <b>Karenca</b> </p> |
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</div> |
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<p style="text-align: justify; "> Meso, organi in u¾itna tkiva prašièev: |
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10 dni </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> </p> |
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<p style="text-align: justify; "> <b>Rok uporabnosti</b> </p> |
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</div> |
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<p style="text-align: justify; "> Oznaèen je na ovojnini (36 mesecev). |
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</p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> Naèeto steklenièko je priporoèljivo |
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porabiti v 28 dneh. </p> |
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</div> |
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<p style="text-align: justify; "> </p> |
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</div> |
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<p style="text-align: justify; "> <b>Naèin izdajanja</b> </p> |
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</div> |
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<p style="text-align: justify; "> Na recept. </p> |
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</div> |
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<p style="text-align: justify; "> </p> |
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</div> |
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<p style="text-align: justify; "> <b>Naèin shranjevanja</b> </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> Shranjujte zašèiteno pred svetlobo |
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pri temperaturi do 25 <sup>o</sup>C in nedosegljivo otrokom. </p> |
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</div> |
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<p style="text-align: justify; "> </p> |
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</div> |
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<p style="text-align: justify; "> <b>Številka in datum odloèbe</b> |
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</p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> 323-03-8/00-128, 21.05.2001 </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> <b></b> </p> |
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</div> |
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<p style="text-align: justify; "> Opr<b>ema</b> </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> Prebodna steklenièka s 50 ml oljne |
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raztopine v posamezni ovojnini. </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> <b>Postopek s prazno ovojnino</b> </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> Prazne ovojnine ne smete odvreèi |
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med obièajne komunalne odpadke. </p> |
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</div> |
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<div align="Justify"> |
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<p style="text-align: justify; "> </p> |
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<p style="text-align: justify; "> <b>Proizvajalec</b> </p> |
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<p style="text-align: justify; "> VETERINA d.o.o., HRVAŠKA </p> |
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<p style="text-align: justify; "> PLIVA LJUBLJANA d. o. o., SLOVENIJA </p> |
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<p style="text-align: justify; "> <b>Revid</b><b>irano na seji Komisije |
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za registracijo zdravil za uporabo v veterinarski medicini dne 18.12.2000.</b> |
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