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Revision 1.1 - (show annotations)
Thu Apr 5 12:26:37 2001 UTC (18 years, 3 months ago) by dpavlin
Branch: MAIN
CVS Tags: HEAD
File MIME type: text/html
smpc for veterina

1
2
3 <!--Section Begins--><br>
4
5
6
7
8
9
10 <div align="justify">
11 <p style="text-align: justify;">
12
13
14
15 </p>
16 </div>
17
18
19
20
21
22
23
24
25
26
27
28
29 <div align="justify">
30 <p style="text-align: justify;">
31
32 <b>VETOFLOK</b><b><sup>® </sup></b><b>10%</b>
33
34 </p>
35 </div>
36
37
38
39
40
41
42
43
44
45
46
47
48 <div align="justify">
49 <p style="text-align: justify;">
50
51 <i>powder</i>
52
53 </p>
54 </div>
55
56
57
58
59
60
61
62
63
64
65
66
67 <div align="justify">
68 <p style="text-align: justify;">
69
70 <b></b>
71
72 </p>
73 </div>
74
75
76
77
78
79
80
81
82
83
84
85
86 <div align="justify">
87 <p style="text-align: justify;">
88
89 <b><i>Composition</i></b>
90
91 </p>
92 </div>
93
94
95
96
97
98
99
100
101
102
103
104
105 <div align="justify">
106 <p style="text-align: justify;">
107
108 100 g contain 10 g of enrofloxacin.
109
110 </p>
111 </div>
112
113
114
115
116
117
118
119
120
121
122
123
124 <div align="justify">
125 <p style="text-align: justify;">
126
127
128
129 </p>
130 </div>
131
132
133
134
135
136
137
138
139
140
141
142
143 <div align="justify">
144 <p style="text-align: justify;">
145
146 <b><i>Action</i></b><b></b>
147
148 </p>
149 </div>
150
151
152
153
154
155
156
157
158
159
160
161
162 <div align="justify">
163 <p style="text-align: justify;">
164
165 Enrofloxacin, active ingredient of Vetoflok<b><sup>®</sup></b>, is an antimicrobial, pertaining to floroquinolones. In the sensitive organisms quinolones inhibit the action of DNA gyrase, the enzyme that catalyses DNA replication and mediates in secondary winding of a duplicated DNA. In very low levels it acts against bacteria and mycoplasma. Antimicrobial spectrum of Vetoflok<b><sup>®</sup></b> is very broad and includes major gram-negative and gram-positive bacteria, mycoplasma and Chlamydia (<i>E</i>. <i>coli</i>, <i>Klebsiella</i> spp., <i>Salmonella</i> spp., <i>Proteus</i> spp., <i>Campylobacter</i> spp., <i>Pseudomonas</i> <i>aeruginosa</i>, <i>Bordetella</i> spp., <i>Pasteurella</i> spp., <i>Haemophilus spp.,</i> <i>Staphylococcus</i> spp., <i>Listeria monocytogenes</i>, <i>Corynebacterium</i> spp., <i>Erysipelothrix</i> <i>insidiosa</i> and <i>Clostridium</i> spp.). Post-antibiotic effect is maintained over 4-8 hours. In addition to antibacterial effect of enrofloxacin, there is also the same effect of its basic metabolite - ciprofloxacin. <b></b>
166
167 </p>
168 </div>
169
170
171
172
173
174
175
176
177
178
179
180
181 <div align="justify">
182 <p style="text-align: justify;">
183
184
185
186 </p>
187 </div>
188
189
190
191
192
193
194
195
196
197
198
199
200 <div align="justify">
201 <p style="text-align: justify;">
202
203 Resorption of orally taken Vetoflok<b><sup>®</sup></b> is rapid and complete. Its tissue levels are 2-3 times in excess of plasma-levels. Markedly high enrofloxacin concentration has been recorded in lungs, liver, kidneys, bones and lymphatic nodes. Pharmacodynamic of the preparation is quite different from the majority of to-date similar antibiotics. Vetoflok<b><sup>®</sup></b> is efficient against beta-lactam-, tetracycline-, macrolide-, aminoglycoside- and sulfonamide antibiotics, which is of great value in poultry and swine production.
204
205 </p>
206 </div>
207
208
209
210
211
212
213
214
215
216
217
218
219 <div align="justify">
220 <p style="text-align: justify;">
221
222
223
224 </p>
225 </div>
226
227
228
229
230
231
232
233
234
235
236
237
238 <div align="justify">
239 <p style="text-align: justify;">
240
241 <b><i>Indications</i></b><b></b>
242
243 </p>
244 </div>
245
246
247
248
249
250
251
252
253
254
255
256
257 <div align="justify">
258 <p style="text-align: justify;">
259
260 <i>Poultry:</i>
261
262 </p>
263 </div>
264
265
266
267
268
269
270
271
272
273
274
275
276 <div align="justify">
277 <p style="text-align: justify;">
278
279 Prophylaxis and treatment of primary and secondary respiratory and gastrointestinal infections in hens and turkeys (broilers, fattening turkeys, pullets, parent flocks, i. e. parents of broilers and layers) caused by enrofloxacin-sensitive bacteria and mycoplasma: colisepticemia, mycoplasmosis, CRD, <i>Coryza contagiosa</i>, fowl cholera, salmonellosis, arthritis, erysipelas (turkeys), campylobacteriosis, etc.
280
281 </p>
282 </div>
283
284
285
286
287
288
289
290
291
292
293
294
295 <div align="justify">
296 <p style="text-align: justify;">
297
298
299
300 </p>
301 </div>
302
303
304
305
306
307
308
309
310
311
312
313
314 <div align="justify">
315 <p style="text-align: justify;">
316
317 <i>Swine:</i>
318
319 </p>
320 </div>
321
322
323
324
325
326
327
328
329
330
331
332
333 <div align="justify">
334 <p style="text-align: justify;">
335
336 Prophylaxis and treatment of mixed bacterial and mycoplasmal infections, particularly of the respiratory and gastrointestinal tract, e. g. pasteurellosis, coli diarrhea, coli septicemia, salmonellosis, atrophic rhinitis and enzootic bronchopneumonia.
337
338 </p>
339 </div>
340
341
342
343
344
345
346
347
348
349
350
351
352 <div align="justify">
353 <p style="text-align: justify;">
354
355
356
357 </p>
358 </div>
359
360
361
362
363
364
365
366
367
368
369
370
371 <div align="justify">
372 <p style="text-align: justify;">
373
374 <b><i>Contraindications</i></b><b></b>
375
376 </p>
377 </div>
378
379
380
381
382
383
384
385
386
387
388
389
390 <div align="justify">
391 <p style="text-align: justify;">
392
393 Unknown.
394
395 </p>
396 </div>
397
398
399
400
401
402
403
404
405
406
407
408
409 <div align="justify">
410 <p style="text-align: justify;">
411
412
413
414 </p>
415 </div>
416
417
418
419
420
421
422
423
424
425
426
427
428 <div align="justify">
429 <p style="text-align: justify;">
430
431 <b><i>Administration</i></b><b></b>
432
433 </p>
434 </div>
435
436
437
438
439
440
441
442
443
444
445
446
447 <div align="justify">
448 <p style="text-align: justify;">
449
450 Vetoflok<b><sup>®</sup></b>10% powder is given to poultry and swine homogeneously mixed with flour feed. First mix a specified dose of Vetoflok<b><sup>®</sup></b> with 20-50 kg of feed, and then add to the remaining feed.
451
452 </p>
453 </div>
454
455
456
457
458
459
460
461
462
463
464
465
466 <div align="justify">
467 <p style="text-align: justify;">
468
469
470
471 </p>
472 </div>
473
474
475
476
477
478
479
480
481
482
483
484
485 <div align="justify">
486 <p style="text-align: justify;">
487
488 Colibacillosis is treated over 5 consecutive days, salmonellosis over 10 consecutive days. Other bacterial and mycoplasmal infections are managed over 7 consecutive days.
489
490 </p>
491 </div>
492
493
494
495
496
497
498
499
500
501
502
503
504 <div align="justify">
505 <p style="text-align: justify;">
506
507
508
509 </p>
510 </div>
511
512
513
514
515
516
517
518
519
520
521
522
523 <div align="justify">
524 <p style="text-align: justify;">
525
526 Once prepared use within 3 months.
527
528 </p>
529 </div>
530
531
532
533
534
535
536
537
538
539
540
541
542 <div align="justify">
543 <p style="text-align: justify;">
544
545
546
547 </p>
548 </div>
549
550
551
552
553
554
555
556
557
558
559
560
561 <div align="justify">
562 <p style="text-align: justify;">
563
564 <b><i>Dosage</i></b><b></b>
565
566 </p>
567 </div>
568
569
570
571
572
573
574
575
576
577
578
579
580 <div align="justify">
581 <p style="text-align: justify;">
582
583 <i>Hens:</i>
584
585 </p>
586 </div>
587
588
589
590
591
592
593
594
595
596
597
598
599 <div align="justify">
600 <p style="text-align: justify;">
601
602 All age categories: 1-3 weeks 60 ppm (0.6 kg of powder /1 T of feed); 4-5 weeks 100 ppm (1.0 kg of powder/1 T of feed); therefrom 130 ppm (1.3 kg of powder/1 T of feed). The table shows respective levels of the powder in feed. Older chicks take less feed and, thus, require higher levels of Vetoflok<b><sup>®</sup></b> to guarantee the intake of 10 mg of enrofloxacin/kg of b. w./day.
603
604 </p>
605 </div>
606
607
608
609
610
611
612
613
614
615
616
617
618 <div align="justify">
619 <p style="text-align: justify;">
620
621 <b></b>
622
623 </p>
624 </div>
625
626
627
628
629
630
631
632
633 <table width="80.39%" border="1" cols="4" rows="7">
634 <tr>
635 <td bgcolor="White" width="22.46%" rowspan="1" colspan="1">
636
637 <div align="justify">
638 <p style="text-align: justify;">
639
640
641
642 </p>
643 </div>
644
645
646
647
648 </td>
649
650
651
652
653
654 <td bgcolor="White" width="77.54%" rowspan="1" colspan="3">
655
656 <div align="center">
657 <p style="text-align: center;">
658
659 Enrofloxacin feed levels
660
661 </p>
662 </div>
663
664
665
666
667 </td>
668
669
670
671
672
673
674
675 </tr>
676
677
678
679 <tr>
680 <td bgcolor="White" width="22.46%" rowspan="1" colspan="1">
681
682 <div align="justify">
683 <p style="text-align: justify;">
684
685
686
687 </p>
688 </div>
689
690
691
692
693 </td>
694
695
696
697
698
699 <td bgcolor="White" width="24.49%" rowspan="1" colspan="1">
700
701 <div align="center">
702 <p style="text-align: center;">
703
704 60 ppm
705
706 </p>
707 </div>
708
709
710
711
712
713
714
715
716
717
718
719
720 <div align="center">
721 <p style="text-align: center;">
722
723 aged 1-3 weeks
724
725 </p>
726 </div>
727
728
729
730
731 </td>
732
733
734
735
736
737 <td bgcolor="White" width="26.52%" rowspan="1" colspan="1">
738
739 <div align="center">
740 <p style="text-align: center;">
741
742 100 ppm
743
744 </p>
745 </div>
746
747
748
749
750
751
752
753
754
755
756
757
758 <div align="center">
759 <p style="text-align: center;">
760
761 aged 4-5 weeks
762
763 </p>
764 </div>
765
766
767
768
769 </td>
770
771
772
773
774
775 <td bgcolor="White" width="26.53%" rowspan="1" colspan="1">
776
777 <div align="center">
778 <p style="text-align: center;">
779
780 130 ppm
781
782 </p>
783 </div>
784
785
786
787
788
789
790
791
792
793
794
795
796 <div align="center">
797 <p style="text-align: center;">
798
799 aged &gt; 5 weeks
800
801 </p>
802 </div>
803
804
805
806
807 </td>
808
809
810
811
812
813
814
815 </tr>
816
817
818
819 <tr>
820 <td bgcolor="White" width="22.46%" rowspan="1" colspan="1">
821
822 <div align="justify">
823 <p style="text-align: justify;">
824
825 Amount of feed
826
827 </p>
828 </div>
829
830
831
832
833 </td>
834
835
836
837
838
839 <td bgcolor="White" width="77.54%" rowspan="1" colspan="3">
840
841 <div align="center">
842 <p style="text-align: center;">
843
844 Vetoflok<b><sup>®</sup></b><sup> </sup>10% levels
845
846 </p>
847 </div>
848
849
850
851
852 </td>
853
854
855
856
857
858
859
860 </tr>
861
862
863
864 <tr>
865 <td bgcolor="White" width="22.46%" rowspan="1" colspan="1">
866
867 <div align="justify">
868 <p style="text-align: justify;">
869
870 250 kg
871
872 </p>
873 </div>
874
875
876
877
878 </td>
879
880
881
882
883
884 <td bgcolor="White" width="24.49%" rowspan="1" colspan="1">
885
886 <div align="center">
887 <p style="text-align: center;">
888
889 0.15 kg
890
891 </p>
892 </div>
893
894
895
896
897 </td>
898
899
900
901
902
903 <td bgcolor="White" width="26.52%" rowspan="1" colspan="1">
904
905 <div align="center">
906 <p style="text-align: center;">
907
908 0.25 kg
909
910 </p>
911 </div>
912
913
914
915
916 </td>
917
918
919
920
921
922 <td bgcolor="White" width="26.53%" rowspan="1" colspan="1">
923
924 <div align="center">
925 <p style="text-align: center;">
926
927 0.325 kg
928
929 </p>
930 </div>
931
932
933
934
935 </td>
936
937
938
939
940
941
942
943 </tr>
944
945
946
947 <tr>
948 <td bgcolor="White" width="22.46%" rowspan="1" colspan="1">
949
950 <div align="justify">
951 <p style="text-align: justify;">
952
953 500 kg
954
955 </p>
956 </div>
957
958
959
960
961 </td>
962
963
964
965
966
967 <td bgcolor="White" width="24.49%" rowspan="1" colspan="1">
968
969 <div align="center">
970 <p style="text-align: center;">
971
972 0.30 kg
973
974 </p>
975 </div>
976
977
978
979
980 </td>
981
982
983
984
985
986 <td bgcolor="White" width="26.52%" rowspan="1" colspan="1">
987
988 <div align="center">
989 <p style="text-align: center;">
990
991 0.50 kg
992
993 </p>
994 </div>
995
996
997
998
999 </td>
1000
1001
1002
1003
1004
1005 <td bgcolor="White" width="26.53%" rowspan="1" colspan="1">
1006
1007 <div align="center">
1008 <p style="text-align: center;">
1009
1010 0.650 kg
1011
1012 </p>
1013 </div>
1014
1015
1016
1017
1018 </td>
1019
1020
1021
1022
1023
1024
1025
1026 </tr>
1027
1028
1029
1030 <tr>
1031 <td bgcolor="White" width="22.46%" rowspan="1" colspan="1">
1032
1033 <div align="justify">
1034 <p style="text-align: justify;">
1035
1036 750 kg
1037
1038 </p>
1039 </div>
1040
1041
1042
1043
1044 </td>
1045
1046
1047
1048
1049
1050 <td bgcolor="White" width="24.49%" rowspan="1" colspan="1">
1051
1052 <div align="center">
1053 <p style="text-align: center;">
1054
1055 0.45 kg
1056
1057 </p>
1058 </div>
1059
1060
1061
1062
1063 </td>
1064
1065
1066
1067
1068
1069 <td bgcolor="White" width="26.52%" rowspan="1" colspan="1">
1070
1071 <div align="center">
1072 <p style="text-align: center;">
1073
1074 0.75 kg
1075
1076 </p>
1077 </div>
1078
1079
1080
1081
1082 </td>
1083
1084
1085
1086
1087
1088 <td bgcolor="White" width="26.53%" rowspan="1" colspan="1">
1089
1090 <div align="center">
1091 <p style="text-align: center;">
1092
1093 1.000 kg
1094
1095 </p>
1096 </div>
1097
1098
1099
1100
1101 </td>
1102
1103
1104
1105
1106
1107
1108
1109 </tr>
1110
1111
1112
1113 <tr>
1114 <td bgcolor="White" width="22.46%" rowspan="1" colspan="1">
1115
1116 <div align="justify">
1117 <p style="text-align: justify;">
1118
1119 1000 kg
1120
1121 </p>
1122 </div>
1123
1124
1125
1126
1127 </td>
1128
1129
1130
1131
1132
1133 <td bgcolor="White" width="24.49%" rowspan="1" colspan="1">
1134
1135 <div align="center">
1136 <p style="text-align: center;">
1137
1138 0.60 kg
1139
1140 </p>
1141 </div>
1142
1143
1144
1145
1146 </td>
1147
1148
1149
1150
1151
1152 <td bgcolor="White" width="26.52%" rowspan="1" colspan="1">
1153
1154 <div align="center">
1155 <p style="text-align: center;">
1156
1157 1.00 kg
1158
1159 </p>
1160 </div>
1161
1162
1163
1164
1165 </td>
1166
1167
1168
1169
1170
1171 <td bgcolor="White" width="26.53%" rowspan="1" colspan="1">
1172
1173 <div align="center">
1174 <p style="text-align: center;">
1175
1176 1.300 kg
1177
1178 </p>
1179 </div>
1180
1181
1182
1183
1184 </td>
1185
1186
1187
1188
1189
1190
1191
1192 </tr>
1193
1194 </table>
1195
1196
1197
1198
1199 <div align="justify">
1200 <p style="text-align: justify;">
1201
1202
1203
1204 </p>
1205 </div>
1206
1207
1208
1209
1210
1211
1212
1213
1214
1215
1216
1217
1218 <div align="justify">
1219 <p style="text-align: justify;">
1220
1221 <i>Turkeys: </i>
1222
1223 </p>
1224 </div>
1225
1226
1227
1228
1229
1230
1231
1232
1233
1234
1235
1236
1237 <div align="justify">
1238 <p style="text-align: justify;">
1239
1240 Fattening turkeys: all ages are given 100 ppm of enrofloxacin over 5 consecutive days, i. e. 1.0 kg of powder/ 1 T of feed.
1241
1242 </p>
1243 </div>
1244
1245
1246
1247
1248
1249
1250
1251
1252
1253
1254
1255
1256 <div align="justify">
1257 <p style="text-align: justify;">
1258
1259
1260
1261 </p>
1262 </div>
1263
1264
1265
1266
1267
1268
1269
1270
1271
1272
1273
1274
1275 <div align="justify">
1276 <p style="text-align: justify;">
1277
1278 <i>Swine: </i>
1279
1280 </p>
1281 </div>
1282
1283
1284
1285
1286
1287
1288
1289
1290
1291
1292
1293
1294 <div align="justify">
1295 <p style="text-align: justify;">
1296
1297 To administer 2.5 mg/kg of b. w./day it is recommended to mix enrofloxacin with feed in the level of 75 ppm (0.75 kg of Vetoflok<b><sup>®</sup></b> /1 T of feed); for the dose of 5.0 mg/kg of b. w./day the level is 150 ppm (1.5 kg Vetoflok<b><sup>®</sup></b>/1 T of feed). In severe or chronic respiratory infections and salmonellosis, enrofloxacin is given in the concentration of 150 ppm.
1298
1299 </p>
1300 </div>
1301
1302
1303
1304
1305
1306
1307
1308
1309
1310
1311
1312
1313 <div align="justify">
1314 <p style="text-align: justify;">
1315
1316
1317
1318 </p>
1319 </div>
1320
1321
1322
1323
1324
1325
1326
1327
1328
1329
1330
1331
1332 <div align="justify">
1333 <p style="text-align: justify;">
1334
1335 Colibacillosis is usually treated over 5 consecutive days, salmonellosis over 10 consecutive days and other bacterial and mycoplasmal infections over 7 consecutive days.
1336
1337 </p>
1338 </div>
1339
1340
1341
1342
1343
1344
1345
1346
1347
1348
1349
1350
1351 <div align="justify">
1352 <p style="text-align: justify;">
1353
1354
1355
1356 </p>
1357 </div>
1358
1359
1360
1361
1362
1363
1364
1365
1366 <table width="75.47%" border="1" cols="3" rows="7">
1367 <tr>
1368 <td bgcolor="White" width="23.92%" rowspan="1" colspan="1">
1369
1370 <div align="justify">
1371 <p style="text-align: justify;">
1372
1373
1374
1375 </p>
1376 </div>
1377
1378
1379
1380
1381 </td>
1382
1383
1384
1385
1386
1387 <td bgcolor="White" width="76.08%" rowspan="1" colspan="2">
1388
1389 <div align="center">
1390 <p style="text-align: center;">
1391
1392 Enrofloxacin feed levels and dosage
1393
1394 </p>
1395 </div>
1396
1397
1398
1399
1400 </td>
1401
1402
1403
1404
1405
1406
1407
1408 </tr>
1409
1410
1411
1412 <tr>
1413 <td bgcolor="White" width="23.92%" rowspan="1" colspan="1">
1414
1415 <div align="justify">
1416 <p style="text-align: justify;">
1417
1418
1419
1420 </p>
1421 </div>
1422
1423
1424
1425
1426 </td>
1427
1428
1429
1430
1431
1432 <td bgcolor="White" width="34.78%" rowspan="1" colspan="1">
1433
1434 <div align="center">
1435 <p style="text-align: center;">
1436
1437 75 ppm
1438
1439 </p>
1440 </div>
1441
1442
1443
1444
1445
1446
1447
1448
1449
1450
1451
1452
1453 <div align="center">
1454 <p style="text-align: center;">
1455
1456 2.5 mg/kg of b.w./day
1457
1458 </p>
1459 </div>
1460
1461
1462
1463
1464 </td>
1465
1466
1467
1468
1469
1470 <td bgcolor="White" width="41.30%" rowspan="1" colspan="1">
1471
1472 <div align="center">
1473 <p style="text-align: center;">
1474
1475 150 ppm
1476
1477 </p>
1478 </div>
1479
1480
1481
1482
1483
1484
1485
1486
1487
1488
1489
1490
1491 <div align="center">
1492 <p style="text-align: center;">
1493
1494 5.0 mg/kg of b.w./day
1495
1496 </p>
1497 </div>
1498
1499
1500
1501
1502 </td>
1503
1504
1505
1506
1507
1508
1509
1510 </tr>
1511
1512
1513
1514 <tr>
1515 <td bgcolor="White" width="23.92%" rowspan="1" colspan="1">
1516
1517 <div align="justify">
1518 <p style="text-align: justify;">
1519
1520 Amount of feed
1521
1522 </p>
1523 </div>
1524
1525
1526
1527
1528 </td>
1529
1530
1531
1532
1533
1534 <td bgcolor="White" width="76.08%" rowspan="1" colspan="2">
1535
1536 <div align="center">
1537 <p style="text-align: center;">
1538
1539 Vetoflok<b><sup>®</sup></b> levels
1540
1541 </p>
1542 </div>
1543
1544
1545
1546
1547 </td>
1548
1549
1550
1551
1552
1553
1554
1555 </tr>
1556
1557
1558
1559 <tr>
1560 <td bgcolor="White" width="23.92%" rowspan="1" colspan="1">
1561
1562 <div align="justify">
1563 <p style="text-align: justify;">
1564
1565 250 kg
1566
1567 </p>
1568 </div>
1569
1570
1571
1572
1573 </td>
1574
1575
1576
1577
1578
1579 <td bgcolor="White" width="34.78%" rowspan="1" colspan="1">
1580
1581 <div align="right">
1582 <p style="text-align: right;">
1583
1584 0.190 kg
1585
1586 </p>
1587 </div>
1588
1589
1590
1591
1592 </td>
1593
1594
1595
1596
1597
1598 <td bgcolor="White" width="41.30%" rowspan="1" colspan="1">
1599
1600 <div align="right">
1601 <p style="text-align: right;">
1602
1603 0.375 kg
1604
1605 </p>
1606 </div>
1607
1608
1609
1610
1611 </td>
1612
1613
1614
1615
1616
1617
1618
1619 </tr>
1620
1621
1622
1623 <tr>
1624 <td bgcolor="White" width="23.92%" rowspan="1" colspan="1">
1625
1626 <div align="justify">
1627 <p style="text-align: justify;">
1628
1629 500 kg
1630
1631 </p>
1632 </div>
1633
1634
1635
1636
1637 </td>
1638
1639
1640
1641
1642
1643 <td bgcolor="White" width="34.78%" rowspan="1" colspan="1">
1644
1645 <div align="right">
1646 <p style="text-align: right;">
1647
1648 0.375 kg
1649
1650 </p>
1651 </div>
1652
1653
1654
1655
1656 </td>
1657
1658
1659
1660
1661
1662 <td bgcolor="White" width="41.30%" rowspan="1" colspan="1">
1663
1664 <div align="right">
1665 <p style="text-align: right;">
1666
1667 0.750 kg
1668
1669 </p>
1670 </div>
1671
1672
1673
1674
1675 </td>
1676
1677
1678
1679
1680
1681
1682
1683 </tr>
1684
1685
1686
1687 <tr>
1688 <td bgcolor="White" width="23.92%" rowspan="1" colspan="1">
1689
1690 <div align="justify">
1691 <p style="text-align: justify;">
1692
1693 750 kg
1694
1695 </p>
1696 </div>
1697
1698
1699
1700
1701 </td>
1702
1703
1704
1705
1706
1707 <td bgcolor="White" width="34.78%" rowspan="1" colspan="1">
1708
1709 <div align="right">
1710 <p style="text-align: right;">
1711
1712 0.565 kg
1713
1714 </p>
1715 </div>
1716
1717
1718
1719
1720 </td>
1721
1722
1723
1724
1725
1726 <td bgcolor="White" width="41.30%" rowspan="1" colspan="1">
1727
1728 <div align="right">
1729 <p style="text-align: right;">
1730
1731 1.125 kg
1732
1733 </p>
1734 </div>
1735
1736
1737
1738
1739 </td>
1740
1741
1742
1743
1744
1745
1746
1747 </tr>
1748
1749
1750
1751 <tr>
1752 <td bgcolor="White" width="23.92%" rowspan="1" colspan="1">
1753
1754 <div align="justify">
1755 <p style="text-align: justify;">
1756
1757 1000 kg
1758
1759 </p>
1760 </div>
1761
1762
1763
1764
1765 </td>
1766
1767
1768
1769
1770
1771 <td bgcolor="White" width="34.78%" rowspan="1" colspan="1">
1772
1773 <div align="right">
1774 <p style="text-align: right;">
1775
1776 0.750 kg
1777
1778 </p>
1779 </div>
1780
1781
1782
1783
1784 </td>
1785
1786
1787
1788
1789
1790 <td bgcolor="White" width="41.30%" rowspan="1" colspan="1">
1791
1792 <div align="right">
1793 <p style="text-align: right;">
1794
1795 1.500 kg
1796
1797 </p>
1798 </div>
1799
1800
1801
1802
1803 </td>
1804
1805
1806
1807
1808
1809
1810
1811 </tr>
1812
1813 </table>
1814
1815
1816
1817
1818 <div align="justify">
1819 <p style="text-align: justify;">
1820
1821
1822
1823 </p>
1824 </div>
1825
1826
1827
1828
1829
1830
1831
1832
1833
1834
1835
1836
1837 <div align="justify">
1838 <p style="text-align: justify;">
1839
1840 <b><i>Warnings, precautions and interactions</i></b><b></b>
1841
1842 </p>
1843 </div>
1844
1845
1846
1847
1848
1849
1850
1851
1852
1853
1854
1855
1856 <div align="justify">
1857 <p style="text-align: justify;">
1858
1859 Enrofloxacin may be given concomitantly with coccidiostatics.
1860
1861 </p>
1862 </div>
1863
1864
1865
1866
1867
1868
1869
1870
1871
1872
1873
1874
1875 <div align="justify">
1876 <p style="text-align: justify;">
1877
1878
1879
1880 </p>
1881 </div>
1882
1883
1884
1885
1886
1887
1888
1889
1890
1891
1892
1893
1894 <div align="justify">
1895 <p style="text-align: justify;">
1896
1897 To prevent diminishing of antimicrobial effect, Vetoflok<b><sup>® </sup></b>should not be given concurrently with tetracycline and macrolide antibiotics.
1898
1899 </p>
1900 </div>
1901
1902
1903
1904
1905
1906
1907
1908
1909
1910
1911
1912
1913 <div align="justify">
1914 <p style="text-align: justify;">
1915
1916
1917
1918 </p>
1919 </div>
1920
1921
1922
1923
1924
1925
1926
1927
1928
1929
1930
1931
1932 <div align="justify">
1933 <p style="text-align: justify;">
1934
1935 Sick animals taking scarce feed should be treated with Vetoflok<b><sup>®</sup></b> in drinking water, or preferably parenterally.
1936
1937 </p>
1938 </div>
1939
1940
1941
1942
1943
1944
1945
1946
1947
1948
1949
1950
1951 <div align="justify">
1952 <p style="text-align: justify;">
1953
1954
1955
1956 </p>
1957 </div>
1958
1959
1960
1961
1962
1963
1964
1965
1966
1967
1968
1969
1970 <div align="justify">
1971 <p style="text-align: justify;">
1972
1973 If after three days of treatment there is no improvement, perform sensitivity test.
1974
1975 </p>
1976 </div>
1977
1978
1979
1980
1981
1982
1983
1984
1985
1986
1987
1988
1989 <div align="justify">
1990 <p style="text-align: justify;">
1991
1992
1993
1994 </p>
1995 </div>
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008 <div align="justify">
2009 <p style="text-align: justify;">
2010
2011 Enrofloxacin is not potent enough to manage streptococcal infections.
2012
2013 </p>
2014 </div>
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
2027 <div align="justify">
2028 <p style="text-align: justify;">
2029
2030
2031
2032 </p>
2033 </div>
2034
2035
2036
2037
2038
2039
2040
2041
2042
2043
2044
2045
2046 <div align="justify">
2047 <p style="text-align: justify;">
2048
2049 Treatment of fowl salmonellosis alleviates clinical symptoms of the disease and reduces mortality and concomitantly reduces salmonella excretion after several weeks. However, enrofloxacin cannot entirely eradicate salmonellosis and mycoplasmosis from the flocks.
2050
2051 </p>
2052 </div>
2053
2054
2055
2056
2057
2058
2059
2060
2061
2062
2063
2064
2065 <div align="justify">
2066 <p style="text-align: justify;">
2067
2068
2069
2070 </p>
2071 </div>
2072
2073
2074
2075
2076
2077
2078
2079
2080
2081
2082
2083
2084 <div align="justify">
2085 <p style="text-align: justify;">
2086
2087
2088
2089 </p>
2090 </div>
2091
2092
2093
2094
2095
2096
2097
2098
2099
2100
2101
2102
2103 <div align="justify">
2104 <p style="text-align: justify;">
2105
2106 When using avoid contact with skin and mucosa. Wear face/eyes protection, suitable protective clothing and shoes. Do not smoke, eat or drink. After handling thoroughly wash the hands with water and soap.
2107
2108 </p>
2109 </div>
2110
2111
2112
2113
2114
2115
2116
2117
2118
2119
2120
2121
2122 <div align="justify">
2123 <p style="text-align: justify;">
2124
2125
2126
2127 </p>
2128 </div>
2129
2130
2131
2132
2133
2134
2135
2136
2137
2138
2139
2140
2141 <div align="justify">
2142 <p style="text-align: justify;">
2143
2144 Equipment and leftovers must be disposed of in a safe way.
2145
2146 </p>
2147 </div>
2148
2149
2150
2151
2152
2153
2154
2155
2156
2157
2158
2159
2160 <div align="justify">
2161 <p style="text-align: justify;">
2162
2163
2164
2165 </p>
2166 </div>
2167
2168
2169
2170
2171
2172
2173
2174
2175
2176
2177
2178
2179 <div align="justify">
2180 <p style="text-align: justify;">
2181
2182 <b><i>Withdrawal</i></b>
2183
2184 </p>
2185 </div>
2186
2187
2188
2189
2190
2191
2192
2193
2194
2195
2196
2197
2198 <div align="justify">
2199 <p style="text-align: justify;">
2200
2201 Meat, organs and other edible tissues -
2202
2203 </p>
2204 </div>
2205
2206
2207
2208
2209
2210
2211
2212
2213
2214
2215
2216
2217 <div align="justify">
2218 <p style="text-align: justify;">
2219
2220 Swine and hens 8 days
2221
2222 </p>
2223 </div>
2224
2225
2226
2227
2228
2229
2230
2231
2232
2233
2234
2235
2236 <div align="justify">
2237 <p style="text-align: justify;">
2238
2239 Turkeys 10 days
2240
2241 </p>
2242 </div>
2243
2244
2245
2246
2247
2248
2249
2250
2251
2252
2253
2254
2255 <div align="justify">
2256 <p style="text-align: justify;">
2257
2258 Eggs 9 days
2259
2260 </p>
2261 </div>
2262
2263
2264
2265
2266
2267
2268
2269
2270
2271
2272
2273
2274 <div align="justify">
2275 <p style="text-align: justify;">
2276
2277
2278
2279 </p>
2280 </div>
2281
2282
2283
2284
2285
2286
2287
2288
2289
2290
2291
2292
2293 <div align="justify">
2294 <p style="text-align: justify;">
2295
2296 <b><i>Storage</i></b>
2297
2298 </p>
2299 </div>
2300
2301
2302
2303
2304
2305
2306
2307
2308
2309
2310
2311
2312 <div align="justify">
2313 <p style="text-align: justify;">
2314
2315 Store in a dry and dark place at controlled room temperature (15-25°C). Keep away from children.
2316
2317 </p>
2318 </div>
2319
2320
2321
2322
2323
2324
2325
2326
2327
2328
2329
2330
2331 <div align="justify">
2332 <p style="text-align: justify;">
2333
2334
2335
2336 </p>
2337 </div>
2338
2339
2340
2341
2342
2343
2344
2345
2346
2347
2348
2349
2350 <div align="justify">
2351 <p style="text-align: justify;">
2352
2353 <b><i>Shelf life</i></b>
2354
2355 </p>
2356 </div>
2357
2358
2359
2360
2361
2362
2363
2364
2365
2366
2367
2368
2369 <div align="justify">
2370 <p style="text-align: justify;">
2371
2372 Denoted on the packaging (2 years in the original pack).
2373
2374 </p>
2375 </div>
2376
2377
2378
2379
2380
2381
2382
2383
2384
2385
2386
2387
2388 <div align="justify">
2389 <p style="text-align: justify;">
2390
2391
2392
2393 </p>
2394 </div>
2395
2396
2397
2398
2399
2400
2401
2402
2403
2404
2405
2406
2407 <div align="justify">
2408 <p style="text-align: justify;">
2409
2410 <b><i>Legal category</i></b>
2411
2412 </p>
2413 </div>
2414
2415
2416
2417
2418
2419
2420
2421
2422
2423
2424
2425
2426 <div align="justify">
2427 <p style="text-align: justify;">
2428
2429 On prescription only.
2430
2431 </p>
2432 </div>
2433
2434
2435
2436
2437
2438
2439
2440
2441
2442
2443
2444
2445 <div align="justify">
2446 <p style="text-align: justify;">
2447
2448
2449
2450 </p>
2451 </div>
2452
2453
2454
2455
2456
2457
2458
2459
2460
2461
2462
2463
2464 <div align="justify">
2465 <p style="text-align: justify;">
2466
2467 <b><i>Supply</i></b>
2468
2469 </p>
2470 </div>
2471
2472
2473
2474
2475
2476
2477
2478
2479
2480
2481
2482
2483 <div align="justify">
2484 <p style="text-align: justify;">
2485
2486 Bags with 100 g,1 kg and 5 kg.
2487
2488 </p>
2489 </div>
2490
2491
2492
2493
2494
2495
2496
2497
2498
2499
2500
2501
2502 <div align="justify">
2503 <p style="text-align: justify;">
2504
2505
2506
2507 </p>
2508 </div>
2509
2510
2511
2512
2513
2514
2515
2516
2517
2518
2519
2520
2521 <div align="justify">
2522 <p style="text-align: justify;">
2523
2524 <b><i>Manufacturer</i></b>
2525
2526 </p>
2527 </div>
2528
2529
2530
2531
2532
2533
2534
2535
2536
2537
2538
2539
2540 <div align="justify">
2541 <p style="text-align: justify;">
2542
2543 VETERINA Animal Health Ltd., Croatia
2544
2545 </p>
2546 </div>
2547
2548
2549
2550
2551
2552
2553
2554
2555
2556
2557
2558
2559 <div align="justify">
2560 <p style="text-align: justify;">
2561
2562
2563
2564 </p>
2565 </div>
2566
2567
2568
2569
2570
2571
2572
2573
2574
2575
2576
2577
2578 <div align="justify">
2579 <p style="text-align: justify;">
2580
2581 <b></b>
2582
2583 </p>
2584 </div>
2585
2586
2587
2588
2589
2590
2591
2592
2593
2594
2595
2596
2597 <div align="left">
2598 <p style="text-align: left;">
2599
2600
2601
2602 </p>
2603 </div>
2604
2605
2606
2607
2608
2609
2610
2611 <!--Section Ends-->
2612
2613
2614
2615
2616
2617
2618
2619

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