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Revision 1.1 - (show annotations)
Thu Apr 5 12:26:37 2001 UTC (22 years, 11 months ago) by dpavlin
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smpc for veterina

1
2
3 <!--Section Begins--><br>
4
5
6
7
8
9
10 <div align="justify">
11 <p style="text-align: justify;">
12
13
14
15 </p>
16 </div>
17
18
19
20
21
22
23
24
25
26
27
28
29 <div align="justify">
30 <p style="text-align: justify;">
31
32 <b>SIMIVET</b><b><sup>®</sup></b><b>15%</b>
33
34 </p>
35 </div>
36
37
38
39
40
41
42
43
44
45
46
47
48 <div align="justify">
49 <p style="text-align: justify;">
50
51 <i>injection suspension</i>
52
53 </p>
54 </div>
55
56
57
58
59
60
61
62
63
64
65
66
67 <div align="justify">
68 <p style="text-align: justify;">
69
70 <b></b>
71
72 </p>
73 </div>
74
75
76
77
78
79
80
81
82
83
84
85
86 <div align="justify">
87 <p style="text-align: justify;">
88
89 <b><i>Composition</i></b><b></b>
90
91 </p>
92 </div>
93
94
95
96
97
98
99
100
101
102
103
104
105 <div align="justify">
106 <p style="text-align: justify;">
107
108 1 mL contains 150 mg of amoxicillin as amoxicillin trihydrate.
109
110 </p>
111 </div>
112
113
114
115
116
117
118
119
120
121
122
123
124 <div align="justify">
125 <p style="text-align: justify;">
126
127
128
129 </p>
130 </div>
131
132
133
134
135
136
137
138
139
140
141
142
143 <div align="justify">
144 <p style="text-align: justify;">
145
146 <b>Action</b>
147
148 </p>
149 </div>
150
151
152
153
154
155
156
157
158
159
160
161
162 <div align="justify">
163 <p style="text-align: justify;">
164
165 Amoxicillin is a semi-synthetic penicillin of a broader spectrum in relation to the source benzylpenicillin. As other beta-lactam antibiotics, during bacterial growth it interferes with the synthesis of its cell wall, thus exerting its bactericidal effect. Antimicrobial spectrum of Simivet<b><sup>®</sup></b> covers many gram-positive and gram-negative bacteria: <i>Streptococcus</i> spp., <i>Staphylococcus</i> spp., <i>Erysipelothrix insidiosa</i>, <i>Actinomyces</i> spp., <i>Clostridium</i> spp., <i>Corynebacterium</i> spp., <i>E. coli</i>, <i>Salmonella</i> spp., <i>Actinobacillus</i> spp., <i>Bordetella bronchiseptica</i>, <i>Fusobacterium</i> spp., <i>Haemophilus</i> spp., <i>Moraxella</i> spp., <i>Pasteurella</i> spp., <i>Proteus mirabilis,</i> etc.
166
167 </p>
168 </div>
169
170
171
172
173
174
175
176
177
178
179
180
181 <div align="justify">
182 <p style="text-align: justify;">
183
184
185
186 </p>
187 </div>
188
189
190
191
192
193
194
195
196
197
198
199
200 <div align="justify">
201 <p style="text-align: justify;">
202
203 After i. m. or s. c. administration of Simivet<b><sup>®</sup></b> peak plasma concentrations of amoxicillin are achieved in 2-hours time. Injection suspension is formulated so that a single dose maintains its effective level over 24 hours. Simivet<b><sup>®</sup></b><sup> </sup>is well distributed in majority of tissues, with markedly high levels attained in parenchymal organs, urine and bile. Amoxicillin readily passes through the inflamed respiratory tract membranes to bronchial mucus, thus aiding the treatment of respiratory infections. It is not active upon bacterial beta-lactamase, while bacterial resistance to it is built gradually. Toxicity of amoxicillin is negligible. The doses in excess of the recommended ones are well tolerated.
204
205 </p>
206 </div>
207
208
209
210
211
212
213
214
215
216
217
218
219 <div align="justify">
220 <p style="text-align: justify;">
221
222
223
224 </p>
225 </div>
226
227
228
229
230
231
232
233
234
235
236
237
238 <div align="justify">
239 <p style="text-align: justify;">
240
241 <b><i>Indications</i></b>
242
243 </p>
244 </div>
245
246
247
248
249
250
251
252
253
254
255
256
257 <div align="justify">
258 <p style="text-align: justify;">
259
260 Simivet<b><sup>®</sup></b>15% suspension is given to swine, cattle, sheep, dogs and cats for the treatment of general and local, primary and secondary infections due to gram-negative and gram-positive bacteria sensitive to amoxicillin. Major indications are:
261
262 </p>
263 </div>
264
265
266
267
268
269
270
271
272
273
274
275
276 <div align="justify">
277 <p style="text-align: justify;">
278
279 - general infections, particularly septicemia;
280
281 </p>
282 </div>
283
284
285
286
287
288
289
290
291
292
293
294
295 <div align="justify">
296 <p style="text-align: justify;">
297
298 - secondary bacterial infections as the outcome of viral diseases;
299
300 </p>
301 </div>
302
303
304
305
306
307
308
309
310
311
312
313
314 <div align="justify">
315 <p style="text-align: justify;">
316
317 - respiratory infections, e. g. bronchopneumonia in the fattening steers;
318
319 </p>
320 </div>
321
322
323
324
325
326
327
328
329
330
331
332
333 <div align="justify">
334 <p style="text-align: justify;">
335
336 - gastrointestinal infections;
337
338 </p>
339 </div>
340
341
342
343
344
345
346
347
348
349
350
351
352 <div align="justify">
353 <p style="text-align: justify;">
354
355 - genitourinary infections including cystitis and metritis;
356
357 </p>
358 </div>
359
360
361
362
363
364
365
366
367
368
369
370
371 <div align="justify">
372 <p style="text-align: justify;">
373
374 - skin and soft tissue infections: abscess, phlegmon, postoperative infections, omphalitis, panarthritis, paronychia, etc.;
375
376 </p>
377 </div>
378
379
380
381
382
383
384
385
386
387
388
389
390 <div align="justify">
391 <p style="text-align: justify;">
392
393 - acute mastitis in cows with the change in general condition and concomitant intramammary treatment;
394
395 </p>
396 </div>
397
398
399
400
401
402
403
404
405
406
407
408
409 <div align="justify">
410 <p style="text-align: justify;">
411
412 - MMA syndrome in sows and erysipelas.
413
414 </p>
415 </div>
416
417
418
419
420
421
422
423
424
425
426
427
428 <div align="justify">
429 <p style="text-align: justify;">
430
431
432
433 </p>
434 </div>
435
436
437
438
439
440
441
442
443
444
445
446
447 <div align="justify">
448 <p style="text-align: justify;">
449
450 <b><i>Contraindications</i></b>
451
452 </p>
453 </div>
454
455
456
457
458
459
460
461
462
463
464
465
466 <div align="justify">
467 <p style="text-align: justify;">
468
469 Simivet<b><sup>®</sup></b><sup> </sup>injection suspension should not be given by intravenous or intrathecal route.
470
471 </p>
472 </div>
473
474
475
476
477
478
479
480
481
482
483
484
485 <div align="justify">
486 <p style="text-align: justify;">
487
488
489
490 </p>
491 </div>
492
493
494
495
496
497
498
499
500
501
502
503
504 <div align="justify">
505 <p style="text-align: justify;">
506
507 Amoxicillin injection suspension should not be administered to small monogastric herbivore, such as rabbits, guinea-pigs, hamsters, etc.
508
509 </p>
510 </div>
511
512
513
514
515
516
517
518
519
520
521
522
523 <div align="justify">
524 <p style="text-align: justify;">
525
526
527
528 </p>
529 </div>
530
531
532
533
534
535
536
537
538
539
540
541
542 <div align="justify">
543 <p style="text-align: justify;">
544
545 Hypersensitivity to penicillin antibiotics, which is extremely rare.
546
547 </p>
548 </div>
549
550
551
552
553
554
555
556
557
558
559
560
561 <div align="justify">
562 <p style="text-align: justify;">
563
564
565
566 </p>
567 </div>
568
569
570
571
572
573
574
575
576
577
578
579
580 <div align="justify">
581 <p style="text-align: justify;">
582
583 Severe renal impairment accompanied by aneuria or oliguria.
584
585 </p>
586 </div>
587
588
589
590
591
592
593
594
595
596
597
598
599 <div align="justify">
600 <p style="text-align: justify;">
601
602
603
604 </p>
605 </div>
606
607
608
609
610
611
612
613
614
615
616
617
618 <div align="justify">
619 <p style="text-align: justify;">
620
621 <b><i>Administration and dosage</i></b>
622
623 </p>
624 </div>
625
626
627
628
629
630
631
632
633
634
635
636
637 <div align="justify">
638 <p style="text-align: justify;">
639
640 Simivet<b><sup>®</sup></b>15% is given by i. m. (cattle, swine, sheep, dogs and cats) or s. c. injection (dogs and cats). Shake well before use.
641
642 </p>
643 </div>
644
645
646
647
648
649
650
651
652
653
654
655
656 <div align="justify">
657 <p style="text-align: justify;">
658
659
660
661 </p>
662 </div>
663
664
665
666
667
668
669
670
671
672
673
674
675 <div align="justify">
676 <p style="text-align: justify;">
677
678 Average dose for all animals is 1 mL/20 kg of b. w./day (7 mg of amoxicillin/kg of b. w./day).
679
680 </p>
681 </div>
682
683
684
685
686
687
688
689
690
691
692
693
694 <div align="justify">
695 <p style="text-align: justify;">
696
697
698
699 </p>
700 </div>
701
702
703
704
705
706
707
708
709
710
711
712
713 <div align="justify">
714 <p style="text-align: justify;">
715
716 Application is repeated every 24 hours. Upon remission of the symptoms the treatment is prolonged over 2 additional days (e. g. 5 days).
717
718 </p>
719 </div>
720
721
722
723
724
725
726
727
728
729
730
731
732 <div align="justify">
733 <p style="text-align: justify;">
734
735
736
737 </p>
738 </div>
739
740
741
742
743
744
745
746
747 <table width="100.00%" border="1" cols="3" rows="11">
748 <tr>
749 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
750
751 <div align="center">
752 <p style="text-align: center;">
753
754 Species and classes
755
756 </p>
757 </div>
758
759
760
761
762 </td>
763
764
765
766
767
768 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
769
770 <div align="center">
771 <p style="text-align: center;">
772
773 Body weight (kg)
774
775 </p>
776 </div>
777
778
779
780
781 </td>
782
783
784
785
786
787 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
788
789 <div align="center">
790 <p style="text-align: center;">
791
792 Dose of SIMIVET<b><sup>®</sup></b><sup> </sup> 15%
793
794 </p>
795 </div>
796
797
798
799
800 </td>
801
802
803
804
805
806
807
808 </tr>
809
810
811
812 <tr>
813 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
814
815 <div align="left">
816 <p style="text-align: left;">
817
818 Cattle
819
820 </p>
821 </div>
822
823
824
825
826 </td>
827
828
829
830
831
832 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
833
834 <div align="center">
835 <p style="text-align: center;">
836
837 500
838
839 </p>
840 </div>
841
842
843
844
845 </td>
846
847
848
849
850
851 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
852
853 <div align="center">
854 <p style="text-align: center;">
855
856 **50 mL
857
858 </p>
859 </div>
860
861
862
863
864 </td>
865
866
867
868
869
870
871
872 </tr>
873
874
875
876 <tr>
877 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
878
879 <div align="left">
880 <p style="text-align: left;">
881
882 Calves/steers
883
884 </p>
885 </div>
886
887
888
889
890 </td>
891
892
893
894
895
896 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
897
898 <div align="center">
899 <p style="text-align: center;">
900
901 100
902
903 </p>
904 </div>
905
906
907
908
909 </td>
910
911
912
913
914
915 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
916
917 <div align="center">
918 <p style="text-align: center;">
919
920 5mL
921
922 </p>
923 </div>
924
925
926
927
928 </td>
929
930
931
932
933
934
935
936 </tr>
937
938
939
940 <tr>
941 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
942
943 <div align="left">
944 <p style="text-align: left;">
945
946 Sheep
947
948 </p>
949 </div>
950
951
952
953
954 </td>
955
956
957
958
959
960 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
961
962 <div align="center">
963 <p style="text-align: center;">
964
965 50
966
967 </p>
968 </div>
969
970
971
972
973 </td>
974
975
976
977
978
979 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
980
981 <div align="center">
982 <p style="text-align: center;">
983
984 2.5 mL
985
986 </p>
987 </div>
988
989
990
991
992 </td>
993
994
995
996
997
998
999
1000 </tr>
1001
1002
1003
1004 <tr>
1005 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1006
1007 <div align="left">
1008 <p style="text-align: left;">
1009
1010 Piglets
1011
1012 </p>
1013 </div>
1014
1015
1016
1017
1018 </td>
1019
1020
1021
1022
1023
1024 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1025
1026 <div align="center">
1027 <p style="text-align: center;">
1028
1029 7-10
1030
1031 </p>
1032 </div>
1033
1034
1035
1036
1037 </td>
1038
1039
1040
1041
1042
1043 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1044
1045 <div align="center">
1046 <p style="text-align: center;">
1047
1048 0.5 mL
1049
1050 </p>
1051 </div>
1052
1053
1054
1055
1056 </td>
1057
1058
1059
1060
1061
1062
1063
1064 </tr>
1065
1066
1067
1068 <tr>
1069 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1070
1071 <div align="left">
1072 <p style="text-align: left;">
1073
1074 Gilts
1075
1076 </p>
1077 </div>
1078
1079
1080
1081
1082 </td>
1083
1084
1085
1086
1087
1088 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1089
1090 <div align="center">
1091 <p style="text-align: center;">
1092
1093 70
1094
1095 </p>
1096 </div>
1097
1098
1099
1100
1101 </td>
1102
1103
1104
1105
1106
1107 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1108
1109 <div align="center">
1110 <p style="text-align: center;">
1111
1112 3.5 mL
1113
1114 </p>
1115 </div>
1116
1117
1118
1119
1120 </td>
1121
1122
1123
1124
1125
1126
1127
1128 </tr>
1129
1130
1131
1132 <tr>
1133 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1134
1135 <div align="left">
1136 <p style="text-align: left;">
1137
1138 Sows
1139
1140 </p>
1141 </div>
1142
1143
1144
1145
1146 </td>
1147
1148
1149
1150
1151
1152 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1153
1154 <div align="center">
1155 <p style="text-align: center;">
1156
1157 150
1158
1159 </p>
1160 </div>
1161
1162
1163
1164
1165 </td>
1166
1167
1168
1169
1170
1171 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1172
1173 <div align="center">
1174 <p style="text-align: center;">
1175
1176 7.5 mL
1177
1178 </p>
1179 </div>
1180
1181
1182
1183
1184 </td>
1185
1186
1187
1188
1189
1190
1191
1192 </tr>
1193
1194
1195
1196 <tr>
1197 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1198
1199 <div align="left">
1200 <p style="text-align: left;">
1201
1202 Small dogs
1203
1204 </p>
1205 </div>
1206
1207
1208
1209
1210 </td>
1211
1212
1213
1214
1215
1216 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1217
1218 <div align="center">
1219 <p style="text-align: center;">
1220
1221 10
1222
1223 </p>
1224 </div>
1225
1226
1227
1228
1229 </td>
1230
1231
1232
1233
1234
1235 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1236
1237 <div align="center">
1238 <p style="text-align: center;">
1239
1240 0.5 mL
1241
1242 </p>
1243 </div>
1244
1245
1246
1247
1248 </td>
1249
1250
1251
1252
1253
1254
1255
1256 </tr>
1257
1258
1259
1260 <tr>
1261 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1262
1263 <div align="left">
1264 <p style="text-align: left;">
1265
1266 Medium dogs
1267
1268 </p>
1269 </div>
1270
1271
1272
1273
1274 </td>
1275
1276
1277
1278
1279
1280 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1281
1282 <div align="center">
1283 <p style="text-align: center;">
1284
1285 20
1286
1287 </p>
1288 </div>
1289
1290
1291
1292
1293 </td>
1294
1295
1296
1297
1298
1299 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1300
1301 <div align="center">
1302 <p style="text-align: center;">
1303
1304 1.0 mL
1305
1306 </p>
1307 </div>
1308
1309
1310
1311
1312 </td>
1313
1314
1315
1316
1317
1318
1319
1320 </tr>
1321
1322
1323
1324 <tr>
1325 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1326
1327 <div align="left">
1328 <p style="text-align: left;">
1329
1330 Large dogs
1331
1332 </p>
1333 </div>
1334
1335
1336
1337
1338 </td>
1339
1340
1341
1342
1343
1344 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1345
1346 <div align="center">
1347 <p style="text-align: center;">
1348
1349 35
1350
1351 </p>
1352 </div>
1353
1354
1355
1356
1357 </td>
1358
1359
1360
1361
1362
1363 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1364
1365 <div align="center">
1366 <p style="text-align: center;">
1367
1368 2.5 mL
1369
1370 </p>
1371 </div>
1372
1373
1374
1375
1376 </td>
1377
1378
1379
1380
1381
1382
1383
1384 </tr>
1385
1386
1387
1388 <tr>
1389 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1390
1391 <div align="left">
1392 <p style="text-align: left;">
1393
1394 Cats
1395
1396 </p>
1397 </div>
1398
1399
1400
1401
1402 </td>
1403
1404
1405
1406
1407
1408 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1409
1410 <div align="center">
1411 <p style="text-align: center;">
1412
1413 5
1414
1415 </p>
1416 </div>
1417
1418
1419
1420
1421 </td>
1422
1423
1424
1425
1426
1427 <td bgcolor="White" width="33.33%" rowspan="1" colspan="1">
1428
1429 <div align="center">
1430 <p style="text-align: center;">
1431
1432 0.25 mL
1433
1434 </p>
1435 </div>
1436
1437
1438
1439
1440 </td>
1441
1442
1443
1444
1445
1446
1447
1448 </tr>
1449
1450 </table>
1451
1452
1453
1454
1455 <div align="justify">
1456 <p style="text-align: justify;">
1457
1458
1459
1460 </p>
1461 </div>
1462
1463
1464
1465
1466
1467
1468
1469
1470
1471
1472
1473
1474 <div align="justify">
1475 <p style="text-align: justify;">
1476
1477 ** Doses above 20 mL should be injected at two sites.
1478
1479 </p>
1480 </div>
1481
1482
1483
1484
1485
1486
1487
1488
1489
1490
1491
1492
1493 <div align="justify">
1494 <p style="text-align: justify;">
1495
1496
1497
1498 </p>
1499 </div>
1500
1501
1502
1503
1504
1505
1506
1507
1508
1509
1510
1511
1512 <div align="justify">
1513 <p style="text-align: justify;">
1514
1515 After administering to cats and dogs gently massage the site of application.
1516
1517 </p>
1518 </div>
1519
1520
1521
1522
1523
1524
1525
1526
1527
1528
1529
1530
1531 <div align="justify">
1532 <p style="text-align: justify;">
1533
1534
1535
1536 </p>
1537 </div>
1538
1539
1540
1541
1542
1543
1544
1545
1546
1547
1548
1549
1550 <div align="justify">
1551 <p style="text-align: justify;">
1552
1553 Higher doses efficiently manage gram-negative infections, bacterial inflammations of respiratory tract and diseases in young animals.
1554
1555 </p>
1556 </div>
1557
1558
1559
1560
1561
1562
1563
1564
1565
1566
1567
1568
1569 <div align="justify">
1570 <p style="text-align: justify;">
1571
1572
1573
1574 </p>
1575 </div>
1576
1577
1578
1579
1580
1581
1582
1583
1584
1585
1586
1587
1588 <div align="justify">
1589 <p style="text-align: justify;">
1590
1591 <b><i>Side effects</i></b>
1592
1593 </p>
1594 </div>
1595
1596
1597
1598
1599
1600
1601
1602
1603
1604
1605
1606
1607 <div align="justify">
1608 <p style="text-align: justify;">
1609
1610 Transient swelling may develop at the site of injection, which disappears a few days from administration.
1611
1612 </p>
1613 </div>
1614
1615
1616
1617
1618
1619
1620
1621
1622
1623
1624
1625
1626 <div align="justify">
1627 <p style="text-align: justify;">
1628
1629
1630
1631 </p>
1632 </div>
1633
1634
1635
1636
1637
1638
1639
1640
1641
1642
1643
1644
1645 <div align="justify">
1646 <p style="text-align: justify;">
1647
1648 <b><i>Warnings, precautions and interactions</i></b>
1649
1650 </p>
1651 </div>
1652
1653
1654
1655
1656
1657
1658
1659
1660
1661
1662
1663
1664 <div align="justify">
1665 <p style="text-align: justify;">
1666
1667 Like other penicillin antibiotics, Simivet<b><sup>®</sup></b> suspension is unstable in water. Use dry and sterile needles and syringes for withdrawal of the vaccine from the bottle and for its administration.
1668
1669 </p>
1670 </div>
1671
1672
1673
1674
1675
1676
1677
1678
1679
1680
1681
1682
1683 <div align="justify">
1684 <p style="text-align: justify;">
1685
1686
1687
1688 </p>
1689 </div>
1690
1691
1692
1693
1694
1695
1696
1697
1698
1699
1700
1701
1702 <div align="justify">
1703 <p style="text-align: justify;">
1704
1705 Antimicrobial action of amoxicillin is reduced by concomitant administration of tetracyclines, macrolides and chloramphenicol.
1706
1707 </p>
1708 </div>
1709
1710
1711
1712
1713
1714
1715
1716
1717
1718
1719
1720
1721 <div align="justify">
1722 <p style="text-align: justify;">
1723
1724
1725
1726 </p>
1727 </div>
1728
1729
1730
1731
1732
1733
1734
1735
1736
1737
1738
1739
1740 <div align="justify">
1741 <p style="text-align: justify;">
1742
1743 If after three days of treatment there is no apparent improvement, the preparation may be continued only if laboratory tests show sensitivity of the causative organism to amoxicillin.
1744
1745 </p>
1746 </div>
1747
1748
1749
1750
1751
1752
1753
1754
1755
1756
1757
1758
1759 <div align="justify">
1760 <p style="text-align: justify;">
1761
1762
1763
1764 </p>
1765 </div>
1766
1767
1768
1769
1770
1771
1772
1773
1774
1775
1776
1777
1778 <div align="justify">
1779 <p style="text-align: justify;">
1780
1781 <b><i>Withdrawal</i></b>
1782
1783 </p>
1784 </div>
1785
1786
1787
1788
1789
1790
1791
1792
1793
1794
1795
1796
1797 <div align="justify">
1798 <p style="text-align: justify;">
1799
1800 Meat and other edible tissues 14 days
1801
1802 </p>
1803 </div>
1804
1805
1806
1807
1808
1809
1810
1811
1812
1813
1814
1815
1816 <div align="justify">
1817 <p style="text-align: justify;">
1818
1819 Cow milk 24 hours
1820
1821 </p>
1822 </div>
1823
1824
1825
1826
1827
1828
1829
1830
1831
1832
1833
1834
1835 <div align="justify">
1836 <p style="text-align: justify;">
1837
1838
1839
1840 </p>
1841 </div>
1842
1843
1844
1845
1846
1847
1848
1849
1850
1851
1852
1853
1854 <div align="justify">
1855 <p style="text-align: justify;">
1856
1857 <b><i>Storage</i></b>
1858
1859 </p>
1860 </div>
1861
1862
1863
1864
1865
1866
1867
1868
1869
1870
1871
1872
1873 <div align="justify">
1874 <p style="text-align: justify;">
1875
1876 Store in a dark and cool place (8-15°C). Keep away from children. Avoid freezing.
1877
1878 </p>
1879 </div>
1880
1881
1882
1883
1884
1885
1886
1887
1888
1889
1890
1891
1892 <div align="justify">
1893 <p style="text-align: justify;">
1894
1895
1896
1897 </p>
1898 </div>
1899
1900
1901
1902
1903
1904
1905
1906
1907
1908
1909
1910
1911 <div align="justify">
1912 <p style="text-align: justify;">
1913
1914 <b><i>Shelf life</i></b>
1915
1916 </p>
1917 </div>
1918
1919
1920
1921
1922
1923
1924
1925
1926
1927
1928
1929
1930 <div align="justify">
1931 <p style="text-align: justify;">
1932
1933 Denoted on the packaging (3 years in the original pack).<b><i></i></b>
1934
1935 </p>
1936 </div>
1937
1938
1939
1940
1941
1942
1943
1944
1945
1946
1947
1948
1949 <div align="justify">
1950 <p style="text-align: justify;">
1951
1952
1953
1954 </p>
1955 </div>
1956
1957
1958
1959
1960
1961
1962
1963
1964
1965
1966
1967
1968 <div align="justify">
1969 <p style="text-align: justify;">
1970
1971 Legal category
1972
1973 </p>
1974 </div>
1975
1976
1977
1978
1979
1980
1981
1982
1983
1984
1985
1986
1987 <div align="justify">
1988 <p style="text-align: justify;">
1989
1990 On prescription only.
1991
1992 </p>
1993 </div>
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006 <div align="justify">
2007 <p style="text-align: justify;">
2008
2009
2010
2011 </p>
2012 </div>
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025 <div align="justify">
2026 <p style="text-align: justify;">
2027
2028 <b><i>Supply</i></b>
2029
2030 </p>
2031 </div>
2032
2033
2034
2035
2036
2037
2038
2039
2040
2041
2042
2043
2044 <div align="justify">
2045 <p style="text-align: justify;">
2046
2047 Pierced bottle of 100 mL
2048
2049 </p>
2050 </div>
2051
2052
2053
2054
2055
2056
2057
2058
2059
2060
2061
2062
2063 <div align="justify">
2064 <p style="text-align: justify;">
2065
2066 Box with 6x100 mL.
2067
2068 </p>
2069 </div>
2070
2071
2072
2073
2074
2075
2076
2077
2078
2079
2080
2081
2082 <div align="justify">
2083 <p style="text-align: justify;">
2084
2085
2086
2087 </p>
2088 </div>
2089
2090
2091
2092
2093
2094
2095
2096
2097
2098
2099
2100
2101 <div align="justify">
2102 <p style="text-align: justify;">
2103
2104 <b><i>Manufacturer</i></b>
2105
2106 </p>
2107 </div>
2108
2109
2110
2111
2112
2113
2114
2115
2116
2117
2118
2119
2120 <div align="justify">
2121 <p style="text-align: justify;">
2122
2123 VETERINA Animal Health Ltd., Croatia
2124
2125 </p>
2126 </div>
2127
2128
2129
2130
2131
2132
2133
2134
2135
2136
2137
2138
2139 <div align="justify">
2140 <p style="text-align: justify;">
2141
2142 <b></b>
2143
2144 </p>
2145 </div>
2146
2147
2148
2149
2150
2151
2152
2153
2154
2155
2156
2157
2158 <div align="justify">
2159 <p style="text-align: justify;">
2160
2161
2162
2163 </p>
2164 </div>
2165
2166
2167
2168
2169
2170
2171
2172
2173
2174
2175
2176
2177 <div align="left">
2178 <p style="text-align: left;">
2179
2180
2181
2182 </p>
2183 </div>
2184
2185
2186
2187
2188
2189
2190
2191 <!--Section Ends-->
2192
2193
2194
2195
2196
2197
2198
2199

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