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Revision 1.1 - (show annotations)
Thu Apr 5 12:26:37 2001 UTC (18 years ago) by dpavlin
Branch: MAIN
CVS Tags: HEAD
File MIME type: text/html
smpc for veterina

1
2
3 <!--Section Begins--><br>
4
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9
10 <div align="justify">
11 <p style="text-align: justify;">
12
13
14
15 </p>
16 </div>
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23
24
25
26
27
28
29 <div align="justify">
30 <p style="text-align: justify;">
31
32 <b>NEOCIKLIN MIKS</b><b><sup>®</sup></b><b></b>
33
34 </p>
35 </div>
36
37
38
39
40
41
42
43
44
45
46
47
48 <div align="justify">
49 <p style="text-align: justify;">
50
51 <i>medicated additive</i>
52
53 </p>
54 </div>
55
56
57
58
59
60
61
62
63
64
65
66
67 <div align="justify">
68 <p style="text-align: justify;">
69
70
71
72 </p>
73 </div>
74
75
76
77
78
79
80
81
82
83
84
85
86 <div align="justify">
87 <p style="text-align: justify;">
88
89 <b><i>Composition </i></b>
90
91 </p>
92 </div>
93
94
95
96
97
98
99
100
101
102
103
104
105 <div align="justify">
106 <p style="text-align: justify;">
107
108 1 kg contains:
109
110 </p>
111 </div>
112
113
114
115
116
117
118
119
120
121
122
123
124 <div align="justify">
125 <p style="text-align: justify;">
126
127 Oxytetracycline as oxytetracycline hydrochloride 100 g
128
129 </p>
130 </div>
131
132
133
134
135
136
137
138
139
140
141
142
143 <div align="justify">
144 <p style="text-align: justify;">
145
146 Neomycin as neomycin sulfate 70 g
147
148 </p>
149 </div>
150
151
152
153
154
155
156
157
158
159
160
161
162 <div align="justify">
163 <p style="text-align: justify;">
164
165 Vegetable carrier - ground wheat bran up to 1000 g
166
167 </p>
168 </div>
169
170
171
172
173
174
175
176
177
178
179
180
181 <div align="justify">
182 <p style="text-align: justify;">
183
184
185
186 </p>
187 </div>
188
189
190
191
192
193
194
195
196
197
198
199
200 <div align="justify">
201 <p style="text-align: justify;">
202
203 <b><i>Action</i></b>
204
205 </p>
206 </div>
207
208
209
210
211
212
213
214
215
216
217
218
219 <div align="justify">
220 <p style="text-align: justify;">
221
222 NEOCIKLIN MIKS<b><sup>®</sup></b> contains oxytetracycline i neomycin (NEO) antibiotics complementing one another in their antimicrobial spectrum against major causes of health problems, in the first place in young animals.
223
224 </p>
225 </div>
226
227
228
229
230
231
232
233
234
235
236
237
238 <div align="justify">
239 <p style="text-align: justify;">
240
241
242
243 </p>
244 </div>
245
246
247
248
249
250
251
252
253
254
255
256
257 <div align="justify">
258 <p style="text-align: justify;">
259
260 - Oxytetracycline inhibits protein synthesis in many gram-positive and gram-negative organisms (streptococci, staphylococci, actinomycetes, clostridiae, listeriae, mycoplasmas, spirochetes, chlamydiae, rickettsiae, bordetellae, brucellae, <i>Haemophilus</i> spp., pasteurellae, etc.). When taken orally it is well resorbed exerting its effect in gastrointestinal tract and affected organs and tissues. Oxytetracycline effectively manages chronic respiratory disease (CRD), enzootic pneumonia, pasteurellosis, diarrhea of bacterial etiology, etc.
261
262 </p>
263 </div>
264
265
266
267
268
269
270
271
272
273
274
275
276 <div align="justify">
277 <p style="text-align: justify;">
278
279
280
281 </p>
282 </div>
283
284
285
286
287
288
289
290
291
292
293
294
295 <div align="justify">
296 <p style="text-align: justify;">
297
298 - Aminoglycosidal antibiotic NEO most frequently exerts bactericidal effect, interfering with protein synthesis of some gram-positive, particularly of gram-negative, bacteria (<i>Staphylococcus aureus</i>, <i>Streptococcus haemolyticus</i>, <i>Pasteurella multocida</i>, <i>Corynebacterium</i> spp., <i>Klebsiella</i> spp., <i>Shigella</i> spp. and <i>Salmonella</i> spp.). It is markedly efficient against <i>E. coli</i>, the most frequent cause of diarrhea in young animals. NEO-sulfate is active in the presence of gastrointestinal enzymes, intestinal content and intestinal bacteria. NEOCIKLIN MIKS<b><sup>®</sup></b> inhibits the growth of clostridia and coliform bacteria, thus improving the gain, feed conversion, productivity and immunity of the animals. Resistance to NEO is established slowly. Given that p. o. taken NEO is very hardly resorbed (3-10%) from the gastrointestinal tract, its action is exerted in the intestines. Major part of it is excreted unchanged via faeces.
299
300 </p>
301 </div>
302
303
304
305
306
307
308
309
310
311
312
313
314 <div align="justify">
315 <p style="text-align: justify;">
316
317
318
319 </p>
320 </div>
321
322
323
324
325
326
327
328
329
330
331
332
333 <div align="justify">
334 <p style="text-align: justify;">
335
336 <b><i>Indications</i></b>
337
338 </p>
339 </div>
340
341
342
343
344
345
346
347
348
349
350
351
352 <div align="justify">
353 <p style="text-align: justify;">
354
355 Prophylaxis and treatment of primary and secondary bacterial infections.
356
357 </p>
358 </div>
359
360
361
362
363
364
365
366
367
368
369
370
371 <div align="justify">
372 <p style="text-align: justify;">
373
374
375
376 </p>
377 </div>
378
379
380
381
382
383
384
385
386
387
388
389
390 <div align="justify">
391 <p style="text-align: justify;">
392
393 <i>Swine:</i>
394
395 </p>
396 </div>
397
398
399
400
401
402
403
404
405
406
407
408
409 <div align="justify">
410 <p style="text-align: justify;">
411
412 Neonatal piglets and other categories: supportive treatment of enteritis due to <i>E</i>. <i>coli</i> and of salmonellosis (<i>Salmonella </i>spp.).
413
414 </p>
415 </div>
416
417
418
419
420
421
422
423
424
425
426
427
428 <div align="justify">
429 <p style="text-align: justify;">
430
431
432
433 </p>
434 </div>
435
436
437
438
439
440
441
442
443
444
445
446
447 <div align="justify">
448 <p style="text-align: justify;">
449
450 All categories: control of stress effects (transportation, change of housing, etc.).
451
452 </p>
453 </div>
454
455
456
457
458
459
460
461
462
463
464
465
466 <div align="justify">
467 <p style="text-align: justify;">
468
469
470
471 </p>
472 </div>
473
474
475
476
477
478
479
480
481
482
483
484
485 <div align="justify">
486 <p style="text-align: justify;">
487
488 Piglets and suckling piglets: reduction of the incidence of gastrointestinal disorders during weaning.
489
490 </p>
491 </div>
492
493
494
495
496
497
498
499
500
501
502
503
504 <div align="justify">
505 <p style="text-align: justify;">
506
507
508
509 </p>
510 </div>
511
512
513
514
515
516
517
518
519
520
521
522
523 <div align="justify">
524 <p style="text-align: justify;">
525
526 Piglets/suckling piglets/fattening pigs: prevention of the effects of atrophic rhinitis on gain and feed conversion.
527
528 </p>
529 </div>
530
531
532
533
534
535
536
537
538
539
540
541
542 <div align="justify">
543 <p style="text-align: justify;">
544
545
546
547 </p>
548 </div>
549
550
551
552
553
554
555
556
557
558
559
560
561 <div align="justify">
562 <p style="text-align: justify;">
563
564 Sows/gilts: control of the excretion of bacteria causing enteritis, atrophic rhinitis, etc. by treating the sows and gilts before and after farrowing, i. e. decreasing mortality in piglets and increasing their body weight at weaning.
565
566 </p>
567 </div>
568
569
570
571
572
573
574
575
576
577
578
579
580 <div align="justify">
581 <p style="text-align: justify;">
582
583
584
585 </p>
586 </div>
587
588
589
590
591
592
593
594
595
596
597
598
599 <div align="justify">
600 <p style="text-align: justify;">
601
602 Sows and gilts: reduction of MMA syndrome incidence.
603
604 </p>
605 </div>
606
607
608
609
610
611
612
613
614
615
616
617
618 <div align="justify">
619 <p style="text-align: justify;">
620
621
622
623 </p>
624 </div>
625
626
627
628
629
630
631
632
633
634
635
636
637 <div align="justify">
638 <p style="text-align: justify;">
639
640 <i>Calves</i><b><i>: </i></b> during pre-fattening period.
641
642 </p>
643 </div>
644
645
646
647
648
649
650
651
652
653
654
655
656 <div align="justify">
657 <p style="text-align: justify;">
658
659 Prophylaxis of bacterial enteritis.
660
661 </p>
662 </div>
663
664
665
666
667
668
669
670
671
672
673
674
675 <div align="justify">
676 <p style="text-align: justify;">
677
678
679
680 </p>
681 </div>
682
683
684
685
686
687
688
689
690
691
692
693
694 <div align="justify">
695 <p style="text-align: justify;">
696
697 Reduction of stress effects.
698
699 </p>
700 </div>
701
702
703
704
705
706
707
708
709
710
711
712
713 <div align="justify">
714 <p style="text-align: justify;">
715
716
717
718 </p>
719 </div>
720
721
722
723
724
725
726
727
728
729
730
731
732 <div align="justify">
733 <p style="text-align: justify;">
734
735 <i>Poultry</i><b> </b>(hens and turkeys):
736
737 </p>
738 </div>
739
740
741
742
743
744
745
746
747
748
749
750
751 <div align="justify">
752 <p style="text-align: justify;">
753
754 Reduction of mortality in chicks and poult.
755
756 </p>
757 </div>
758
759
760
761
762
763
764
765
766
767
768
769
770 <div align="justify">
771 <p style="text-align: justify;">
772
773
774
775 </p>
776 </div>
777
778
779
780
781
782
783
784
785
786
787
788
789 <div align="justify">
790 <p style="text-align: justify;">
791
792 Prophylaxis and treatment of bacterial inflammation of the intestines and bacterial infections secondary to e. g. coronavirus enteritis (blue comb disease).
793
794 </p>
795 </div>
796
797
798
799
800
801
802
803
804
805
806
807
808 <div align="justify">
809 <p style="text-align: justify;">
810
811
812
813 </p>
814 </div>
815
816
817
818
819
820
821
822
823
824
825
826
827 <div align="justify">
828 <p style="text-align: justify;">
829
830 Aid in prophylaxis of diseases during stress conditions u (change of housing, vaccination, extreme change of environmental temperature - chilling/overheating, etc.).
831
832 </p>
833 </div>
834
835
836
837
838
839
840
841
842
843
844
845
846 <div align="justify">
847 <p style="text-align: justify;">
848
849
850
851 </p>
852 </div>
853
854
855
856
857
858
859
860
861
862
863
864
865 <div align="justify">
866 <p style="text-align: justify;">
867
868 Control of infectious sinusitits and sinovitis.
869
870 </p>
871 </div>
872
873
874
875
876
877
878
879
880
881
882
883
884 <div align="justify">
885 <p style="text-align: justify;">
886
887
888
889 </p>
890 </div>
891
892
893
894
895
896
897
898
899
900
901
902
903 <div align="justify">
904 <p style="text-align: justify;">
905
906 Prophylaxis of hexamitiasis (<i>Hexamita meleagridis).</i>
907
908 </p>
909 </div>
910
911
912
913
914
915
916
917
918
919
920
921
922 <div align="justify">
923 <p style="text-align: justify;">
924
925
926
927 </p>
928 </div>
929
930
931
932
933
934
935
936
937
938
939
940
941 <div align="justify">
942 <p style="text-align: justify;">
943
944 Prophylaxis and control of chronic respiratory disease complex (CRD), i. e. reduction of mortality and severity of clinical symptoms.
945
946 </p>
947 </div>
948
949
950
951
952
953
954
955
956
957
958
959
960 <div align="justify">
961 <p style="text-align: justify;">
962
963
964
965 </p>
966 </div>
967
968
969
970
971
972
973
974
975
976
977
978
979 <div align="justify">
980 <p style="text-align: justify;">
981
982 <b><i>Contraindications</i></b>
983
984 </p>
985 </div>
986
987
988
989
990
991
992
993
994
995
996
997
998 <div align="justify">
999 <p style="text-align: justify;">
1000
1001 Neociklin Miks<b><sup>®</sup></b> should not be given to the animals with the established allergic reaction to it, which is extremely rare.
1002
1003 </p>
1004 </div>
1005
1006
1007
1008
1009
1010
1011
1012
1013
1014
1015
1016
1017 <div align="justify">
1018 <p style="text-align: justify;">
1019
1020
1021
1022 </p>
1023 </div>
1024
1025
1026
1027
1028
1029
1030
1031
1032
1033
1034
1035
1036 <div align="justify">
1037 <p style="text-align: justify;">
1038
1039 It is inadvisable to administer Neociklin Miks<b><sup>®</sup></b> to the species and categories for which it has not been registered (e. g. sheep, goats, cows and ungulates).
1040
1041 </p>
1042 </div>
1043
1044
1045
1046
1047
1048
1049
1050
1051
1052
1053
1054
1055 <div align="justify">
1056 <p style="text-align: justify;">
1057
1058
1059
1060 </p>
1061 </div>
1062
1063
1064
1065
1066
1067
1068
1069
1070
1071
1072
1073
1074 <div align="justify">
1075 <p style="text-align: justify;">
1076
1077 Neociklin Miks<b><sup>®</sup></b> is contraindicated in severe renal and hepatic impairment.
1078
1079 </p>
1080 </div>
1081
1082
1083
1084
1085
1086
1087
1088
1089
1090
1091
1092
1093 <div align="justify">
1094 <p style="text-align: justify;">
1095
1096
1097
1098 </p>
1099 </div>
1100
1101
1102
1103
1104
1105
1106
1107
1108
1109
1110
1111
1112 <div align="justify">
1113 <p style="text-align: justify;">
1114
1115 <b><i>Administration and dosage</i></b>
1116
1117 </p>
1118 </div>
1119
1120
1121
1122
1123
1124
1125
1126
1127
1128
1129
1130
1131 <div align="justify">
1132 <p style="text-align: justify;">
1133
1134 Neociklin Miks<b><sup>®</sup></b> is given homogeneously mixed with feed in the dose of 0.1-0.25%, i. e. 1.0-2.5 kg/1 T of feed (100-250 ppm of oxytetracycline + 70-175 ppm NEO).
1135
1136 </p>
1137 </div>
1138
1139
1140
1141
1142
1143
1144
1145
1146
1147
1148
1149
1150 <div align="justify">
1151 <p style="text-align: justify;">
1152
1153
1154
1155 </p>
1156 </div>
1157
1158
1159
1160
1161
1162
1163
1164
1165
1166
1167
1168
1169 <div align="justify">
1170 <p style="text-align: justify;">
1171
1172 <i>Swine:</i>
1173
1174 </p>
1175 </div>
1176
1177
1178
1179
1180
1181
1182
1183
1184
1185
1186
1187
1188 <div align="justify">
1189 <p style="text-align: justify;">
1190
1191 Control of diarrhea in the suckling piglets and during stress conditions: the sows are treated from the onset of the suckling period (lactation), i. e. during stress conditions over 5-10 days with the dose of 1-1.5 kg/1 T of feed.
1192
1193 </p>
1194 </div>
1195
1196
1197
1198
1199
1200
1201
1202
1203
1204
1205
1206
1207 <div align="justify">
1208 <p style="text-align: justify;">
1209
1210
1211
1212 </p>
1213 </div>
1214
1215
1216
1217
1218
1219
1220
1221
1222
1223
1224
1225
1226 <div align="justify">
1227 <p style="text-align: justify;">
1228
1229 Control of diarrhea in the suckling and fattening piglets: 1.5 kg/1 T of feed over 10 days.
1230
1231 </p>
1232 </div>
1233
1234
1235
1236
1237
1238
1239
1240
1241
1242
1243
1244
1245 <div align="justify">
1246 <p style="text-align: justify;">
1247
1248
1249
1250 </p>
1251 </div>
1252
1253
1254
1255
1256
1257
1258
1259
1260
1261
1262
1263
1264 <div align="justify">
1265 <p style="text-align: justify;">
1266
1267 Control of stress effects on gain and feed conversion in case of atrophic rhinitis: 1.5 kg/1 T of feed over 10 days or longer, if necessary.
1268
1269 </p>
1270 </div>
1271
1272
1273
1274
1275
1276
1277
1278
1279
1280
1281
1282
1283 <div align="justify">
1284 <p style="text-align: justify;">
1285
1286
1287
1288 </p>
1289 </div>
1290
1291
1292
1293
1294
1295
1296
1297
1298
1299
1300
1301
1302 <div align="justify">
1303 <p style="text-align: justify;">
1304
1305 Reduction of stress effects (weaning, transportation, change of housing, etc.): 1.5 kg/1 T of feed over 5-10 days.
1306
1307 </p>
1308 </div>
1309
1310
1311
1312
1313
1314
1315
1316
1317
1318
1319
1320
1321 <div align="justify">
1322 <p style="text-align: justify;">
1323
1324
1325
1326 </p>
1327 </div>
1328
1329
1330
1331
1332
1333
1334
1335
1336
1337
1338
1339
1340 <div align="justify">
1341 <p style="text-align: justify;">
1342
1343 Treatment of sows and gilts (1-2 weeks before farrowing and 14 days after it) reduces mortality in the piglets and increases their body weight at weaning. Simultaneously it reduces the excretion of bacteria involved in etiology of rhinitis: 1.5 kg/1 T of feed.
1344
1345 </p>
1346 </div>
1347
1348
1349
1350
1351
1352
1353
1354
1355
1356
1357
1358
1359 <div align="justify">
1360 <p style="text-align: justify;">
1361
1362
1363
1364 </p>
1365 </div>
1366
1367
1368
1369
1370
1371
1372
1373
1374
1375
1376
1377
1378 <div align="justify">
1379 <p style="text-align: justify;">
1380
1381 <i>Calves during pre-fattening period:</i>
1382
1383 </p>
1384 </div>
1385
1386
1387
1388
1389
1390
1391
1392
1393
1394
1395
1396
1397 <div align="justify">
1398 <p style="text-align: justify;">
1399
1400 Daily dose for the calves, which are not functional ruminants: 10 g of medicated additive (3 levelled tablespoonfuls/50 kg of b. w.) dissolved in some liquid (tea, water, milk, milk substitute, whey) given over 5 consecutive days. Always prepare a fresh solution.
1401
1402 </p>
1403 </div>
1404
1405
1406
1407
1408
1409
1410
1411
1412
1413
1414
1415
1416 <div align="justify">
1417 <p style="text-align: justify;">
1418
1419
1420
1421 </p>
1422 </div>
1423
1424
1425
1426
1427
1428
1429
1430
1431
1432
1433
1434
1435 <div align="justify">
1436 <p style="text-align: justify;">
1437
1438 Calves over 8 weeks of age are given medicated premix homogeneously mixed with the feed in the dose of 1-2 kg/1 T of feed over 5 consecutive days.
1439
1440 </p>
1441 </div>
1442
1443
1444
1445
1446
1447
1448
1449
1450
1451
1452
1453
1454 <div align="justify">
1455 <p style="text-align: justify;">
1456
1457
1458
1459 </p>
1460 </div>
1461
1462
1463
1464
1465
1466
1467
1468
1469
1470
1471
1472
1473 <div align="justify">
1474 <p style="text-align: justify;">
1475
1476 <i>Broilers and poult</i>
1477
1478 </p>
1479 </div>
1480
1481
1482
1483
1484
1485
1486
1487
1488
1489
1490
1491
1492 <div align="justify">
1493 <p style="text-align: justify;">
1494
1495 Reduction of early mortality: treat the broilers over the first 2 weeks post hatching (1 kg/1 T of feed), and the poult over the first 4 weeks post hatching (0.5-1.0 kg/1 T of feed).
1496
1497 </p>
1498 </div>
1499
1500
1501
1502
1503
1504
1505
1506
1507
1508
1509
1510
1511 <div align="justify">
1512 <p style="text-align: justify;">
1513
1514
1515
1516 </p>
1517 </div>
1518
1519
1520
1521
1522
1523
1524
1525
1526
1527
1528
1529
1530 <div align="justify">
1531 <p style="text-align: justify;">
1532
1533 Prophylaxis and treatment of bacterial and non-specific enteritis (blue comb disease): 2-2.5 kg/T of feed given over 5-7 days or longer, if necessary.
1534
1535 </p>
1536 </div>
1537
1538
1539
1540
1541
1542
1543
1544
1545
1546
1547
1548
1549 <div align="justify">
1550 <p style="text-align: justify;">
1551
1552
1553
1554 </p>
1555 </div>
1556
1557
1558
1559
1560
1561
1562
1563
1564
1565
1566
1567
1568 <div align="justify">
1569 <p style="text-align: justify;">
1570
1571 Aid in prophylaxis of diseases during stress conditions (transportation, change of housing, extreme changes in environmental temperature - chilling/overheating, etc.): 2-2.5 kg/1 T of feed given over 5 days or longer, if necessary.
1572
1573 </p>
1574 </div>
1575
1576
1577
1578
1579
1580
1581
1582
1583
1584
1585
1586
1587 <div align="justify">
1588 <p style="text-align: justify;">
1589
1590
1591
1592 </p>
1593 </div>
1594
1595
1596
1597
1598
1599
1600
1601
1602
1603
1604
1605
1606 <div align="justify">
1607 <p style="text-align: justify;">
1608
1609 Prophylaxis of chronic respiratory disease complex (CRD) - reduction of mortality and severity of clinical symptoms; favourable effect on health condition and profitability of production during CRD: 2.5 kg/1 T of feed given over the first 7 days of life and then again over 5 days during week 5. If CRD clinical symptoms appear treat with 2-2.5 kg/1 T of feed till the end of the fattening period (observe withdrawal period).
1610
1611 </p>
1612 </div>
1613
1614
1615
1616
1617
1618
1619
1620
1621
1622
1623
1624
1625 <div align="justify">
1626 <p style="text-align: justify;">
1627
1628
1629
1630 </p>
1631 </div>
1632
1633
1634
1635
1636
1637
1638
1639
1640
1641
1642
1643
1644 <div align="justify">
1645 <p style="text-align: justify;">
1646
1647 Control of infectious sinovitis and sinusitis: 2.5 kg/1 T of feed given over 5-7 days or longer, if necessary.
1648
1649 </p>
1650 </div>
1651
1652
1653
1654
1655
1656
1657
1658
1659
1660
1661
1662
1663 <div align="justify">
1664 <p style="text-align: justify;">
1665
1666
1667
1668 </p>
1669 </div>
1670
1671
1672
1673
1674
1675
1676
1677
1678
1679
1680
1681
1682 <div align="justify">
1683 <p style="text-align: justify;">
1684
1685 Prophylaxis and treatment of hexamitiasis (<i>Hexamita meleagridis)</i>: 2 kg/1 T of feed over not less than 5-7 days or up to 14 days, if necessary.
1686
1687 </p>
1688 </div>
1689
1690
1691
1692
1693
1694
1695
1696
1697
1698
1699
1700
1701 <div align="justify">
1702 <p style="text-align: justify;">
1703
1704
1705
1706 </p>
1707 </div>
1708
1709
1710
1711
1712
1713
1714
1715
1716
1717
1718
1719
1720 <div align="justify">
1721 <p style="text-align: justify;">
1722
1723 <b><i>Warnings and precautions</i></b>
1724
1725 </p>
1726 </div>
1727
1728
1729
1730
1731
1732
1733
1734
1735
1736
1737
1738
1739 <div align="justify">
1740 <p style="text-align: justify;">
1741
1742 Sick animals taking scarce or insufficient feed should be given Neociklin Miks<b><sup>®</sup></b> dissolved in drinking water or preferably by parenteral route.
1743
1744 </p>
1745 </div>
1746
1747
1748
1749
1750
1751
1752
1753
1754
1755
1756
1757
1758 <div align="justify">
1759 <p style="text-align: justify;">
1760
1761
1762
1763 </p>
1764 </div>
1765
1766
1767
1768
1769
1770
1771
1772
1773
1774
1775
1776
1777 <div align="justify">
1778 <p style="text-align: justify;">
1779
1780 If after three days of treatment there is no apparent improvement, the preparation may be continued only if laboratory tests show sensitivity of the causative organism to oxytetracycline, i. e. NEO.
1781
1782 </p>
1783 </div>
1784
1785
1786
1787
1788
1789
1790
1791
1792
1793
1794
1795
1796 <div align="justify">
1797 <p style="text-align: justify;">
1798
1799
1800
1801 </p>
1802 </div>
1803
1804
1805
1806
1807
1808
1809
1810
1811
1812
1813
1814
1815 <div align="justify">
1816 <p style="text-align: justify;">
1817
1818 Neociklin Miks<b><sup>®</sup></b> should not be given concomitantly with other drugs or medicated additives.
1819
1820 </p>
1821 </div>
1822
1823
1824
1825
1826
1827
1828
1829
1830
1831
1832
1833
1834 <div align="justify">
1835 <p style="text-align: justify;">
1836
1837
1838
1839 </p>
1840 </div>
1841
1842
1843
1844
1845
1846
1847
1848
1849
1850
1851
1852
1853 <div align="justify">
1854 <p style="text-align: justify;">
1855
1856 To ensure homogeneity of mixing with complete feed, add beforehand the required amount of Neociklin Miks<b><sup>®</sup></b> to some feed (e. g. 7-20 kg) or to one of the feed components (e. g. mineral additives).
1857
1858 </p>
1859 </div>
1860
1861
1862
1863
1864
1865
1866
1867
1868
1869
1870
1871
1872 <div align="justify">
1873 <p style="text-align: justify;">
1874
1875
1876
1877 </p>
1878 </div>
1879
1880
1881
1882
1883
1884
1885
1886
1887
1888
1889
1890
1891 <div align="justify">
1892 <p style="text-align: justify;">
1893
1894
1895
1896 </p>
1897 </div>
1898
1899
1900
1901
1902
1903
1904
1905
1906
1907
1908
1909
1910 <div align="justify">
1911 <p style="text-align: justify;">
1912
1913 When using do not smoke, eat or drink. After handling thoroughly wash the hands with water and soap. In case of contact, rinse immediately with plenty of water.
1914
1915 </p>
1916 </div>
1917
1918
1919
1920
1921
1922
1923
1924
1925
1926
1927
1928
1929 <div align="justify">
1930 <p style="text-align: justify;">
1931
1932
1933
1934 </p>
1935 </div>
1936
1937
1938
1939
1940
1941
1942
1943
1944
1945
1946
1947
1948 <div align="justify">
1949 <p style="text-align: justify;">
1950
1951 Packaging and leftovers must be disposed of in a safe way.
1952
1953 </p>
1954 </div>
1955
1956
1957
1958
1959
1960
1961
1962
1963
1964
1965
1966
1967 <div align="justify">
1968 <p style="text-align: justify;">
1969
1970
1971
1972 </p>
1973 </div>
1974
1975
1976
1977
1978
1979
1980
1981
1982
1983
1984
1985
1986 <div align="justify">
1987 <p style="text-align: justify;">
1988
1989 Usual pelleting procedure does not diminish potency of the mixed preparation.
1990
1991 </p>
1992 </div>
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005 <div align="justify">
2006 <p style="text-align: justify;">
2007
2008
2009
2010 </p>
2011 </div>
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024 <div align="justify">
2025 <p style="text-align: justify;">
2026
2027 <b><i>Withdrawal</i></b>
2028
2029 </p>
2030 </div>
2031
2032
2033
2034
2035
2036
2037
2038
2039
2040
2041
2042
2043 <div align="justify">
2044 <p style="text-align: justify;">
2045
2046 Meat, organs and other edible tissues
2047
2048 </p>
2049 </div>
2050
2051
2052
2053
2054
2055
2056
2057
2058
2059
2060
2061
2062 <div align="justify">
2063 <p style="text-align: justify;">
2064
2065 Swine 5 days
2066
2067 </p>
2068 </div>
2069
2070
2071
2072
2073
2074
2075
2076
2077
2078
2079
2080
2081 <div align="justify">
2082 <p style="text-align: justify;">
2083
2084 Calves 7 days
2085
2086 </p>
2087 </div>
2088
2089
2090
2091
2092
2093
2094
2095
2096
2097
2098
2099
2100 <div align="justify">
2101 <p style="text-align: justify;">
2102
2103 Broilers 5 days
2104
2105 </p>
2106 </div>
2107
2108
2109
2110
2111
2112
2113
2114
2115
2116
2117
2118
2119 <div align="justify">
2120 <p style="text-align: justify;">
2121
2122 Turkeys 14 days
2123
2124 </p>
2125 </div>
2126
2127
2128
2129
2130
2131
2132
2133
2134
2135
2136
2137
2138 <div align="justify">
2139 <p style="text-align: justify;">
2140
2141
2142
2143 </p>
2144 </div>
2145
2146
2147
2148
2149
2150
2151
2152
2153
2154
2155
2156
2157 <div align="justify">
2158 <p style="text-align: justify;">
2159
2160 <b><i>Storage</i></b>
2161
2162 </p>
2163 </div>
2164
2165
2166
2167
2168
2169
2170
2171
2172
2173
2174
2175
2176 <div align="justify">
2177 <p style="text-align: justify;">
2178
2179 Store in a dry, ventilated and dark place at the controlled room temperature (15-25°C). Keep away from children.
2180
2181 </p>
2182 </div>
2183
2184
2185
2186
2187
2188
2189
2190
2191
2192
2193
2194
2195 <div align="justify">
2196 <p style="text-align: justify;">
2197
2198
2199
2200 </p>
2201 </div>
2202
2203
2204
2205
2206
2207
2208
2209
2210
2211
2212
2213
2214 <div align="justify">
2215 <p style="text-align: justify;">
2216
2217 <b><i>Legal category</i></b>
2218
2219 </p>
2220 </div>
2221
2222
2223
2224
2225
2226
2227
2228
2229
2230
2231
2232
2233 <div align="justify">
2234 <p style="text-align: justify;">
2235
2236 On prescription only or at veterinarian's written request to prepare.
2237
2238 </p>
2239 </div>
2240
2241
2242
2243
2244
2245
2246
2247
2248
2249
2250
2251
2252 <div align="justify">
2253 <p style="text-align: justify;">
2254
2255
2256
2257 </p>
2258 </div>
2259
2260
2261
2262
2263
2264
2265
2266
2267
2268
2269
2270
2271 <div align="justify">
2272 <p style="text-align: justify;">
2273
2274 <b><i>Shelf life</i></b>
2275
2276 </p>
2277 </div>
2278
2279
2280
2281
2282
2283
2284
2285
2286
2287
2288
2289
2290 <div align="justify">
2291 <p style="text-align: justify;">
2292
2293 Denoted on the packaging (2 years in the original pack).
2294
2295 </p>
2296 </div>
2297
2298
2299
2300
2301
2302
2303
2304
2305
2306
2307
2308
2309 <div align="justify">
2310 <p style="text-align: justify;">
2311
2312
2313
2314 </p>
2315 </div>
2316
2317
2318
2319
2320
2321
2322
2323
2324
2325
2326
2327
2328 <div align="justify">
2329 <p style="text-align: justify;">
2330
2331 Neociklin Miks<b><sup>®</sup></b> mixed with feed or pelleted maintains its activity over 3 months.
2332
2333 </p>
2334 </div>
2335
2336
2337
2338
2339
2340
2341
2342
2343
2344
2345
2346
2347 <div align="justify">
2348 <p style="text-align: justify;">
2349
2350
2351
2352 </p>
2353 </div>
2354
2355
2356
2357
2358
2359
2360
2361
2362
2363
2364
2365
2366 <div align="justify">
2367 <p style="text-align: justify;">
2368
2369 <b><i>Supply</i></b>
2370
2371 </p>
2372 </div>
2373
2374
2375
2376
2377
2378
2379
2380
2381
2382
2383
2384
2385 <div align="justify">
2386 <p style="text-align: justify;">
2387
2388 Polyester/aluminium/polyethylene bags with 200 g and 1000 g and polyethylene/natron bags with 5 kg and 25 kg.
2389
2390 </p>
2391 </div>
2392
2393
2394
2395
2396
2397
2398
2399
2400
2401
2402
2403
2404 <div align="justify">
2405 <p style="text-align: justify;">
2406
2407
2408
2409 </p>
2410 </div>
2411
2412
2413
2414
2415
2416
2417
2418
2419
2420
2421
2422
2423 <div align="justify">
2424 <p style="text-align: justify;">
2425
2426 <b><i>Manufacturer</i></b>
2427
2428 </p>
2429 </div>
2430
2431
2432
2433
2434
2435
2436
2437
2438
2439
2440
2441
2442 <div align="justify">
2443 <p style="text-align: justify;">
2444
2445 VETERINA Animal Health Ltd., Croatia
2446
2447 </p>
2448 </div>
2449
2450
2451
2452
2453
2454
2455
2456
2457
2458
2459
2460
2461 <div align="justify">
2462 <p style="text-align: justify;">
2463
2464
2465
2466 </p>
2467 </div>
2468
2469
2470
2471
2472
2473
2474
2475
2476
2477
2478
2479
2480 <div align="left">
2481 <p style="text-align: left;">
2482
2483
2484
2485 </p>
2486 </div>
2487
2488
2489
2490
2491
2492
2493
2494 <!--Section Ends-->
2495
2496
2497
2498
2499
2500
2501
2502

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