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Revision 1.2 - (show annotations)
Tue Apr 10 11:02:10 2001 UTC (18 years, 2 months ago) by dpavlin
Branch: MAIN
CVS Tags: HEAD
Changes since 1.1: +6 -6 lines
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1
2
3 <!--Section Begins--><br>
4
5
6
7
8
9
10 <div align="justify">
11 <p style="text-align: justify;">
12
13
14
15 </p>
16 </div>
17
18
19
20
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22
23
24
25
26
27
28
29 <div align="justify">
30 <p style="text-align: justify;">
31
32 <b>GEOMYCIN</b><b><sup>®</sup></b><b> 5.5%</b>
33
34 </p>
35 </div>
36
37
38
39
40
41
42
43
44
45
46
47
48 <div align="justify">
49 <p style="text-align: justify;">
50
51 <i>soluble powder</i>
52
53 </p>
54 </div>
55
56
57
58
59
60
61
62
63
64
65
66
67 <div align="justify">
68 <p style="text-align: justify;">
69
70 <b></b>
71
72 </p>
73 </div>
74
75
76
77
78
79
80
81
82
83
84
85
86 <div align="justify">
87 <p style="text-align: justify;">
88
89 <b><i>Composition</i></b>
90
91 </p>
92 </div>
93
94
95
96
97
98
99
100
101
102
103
104
105 <div align="justify">
106 <p style="text-align: justify;">
107
108 1 g contains 55 mg of oxytetracycline hydrochloride.
109
110 </p>
111 </div>
112
113
114
115
116
117
118
119
120
121
122
123
124 <div align="justify">
125 <p style="text-align: justify;">
126
127
128
129 </p>
130 </div>
131
132
133
134
135
136
137
138
139
140
141
142
143 <div align="justify">
144 <p style="text-align: justify;">
145
146 <b><i>Action</i></b>
147
148 </p>
149 </div>
150
151
152
153
154
155
156
157
158
159
160
161
162 <div align="justify">
163 <p style="text-align: justify;">
164
165 Oxytetracycline is a broad-spectrum bacteriostatic antimicrobial antibiotic, which in the sensitive organisms interferes with protein synthesis. It is effective against many gram-positive and gram-negative organisms and inhibits the growth and multiplication of rickettsiae, mycoplasmas, Chlamydiae and actinomycetes. When administered orally, the powder is well resorbed, in the first place from the front part of the small intestines, and after 2-4 hours achieves efficient blood- and tissue-levels. Oxytetracycline is rapidly distributed in the body, its high concentrations can be found in the lungs, kidneys, liver, bile, spleen and bones. Most of it is excreted from the body unchanged, i. e. 20% of the dose via bile and intestines and over 50% through urine.
166
167 </p>
168 </div>
169
170
171
172
173
174
175
176
177
178
179
180
181 <div align="justify">
182 <p style="text-align: justify;">
183
184
185
186 </p>
187 </div>
188
189
190
191
192
193
194
195
196
197
198
199
200 <div align="justify">
201 <p style="text-align: justify;">
202
203 <b><i>Indications</i></b>
204
205 </p>
206 </div>
207
208
209
210
211
212
213
214
215
216
217
218
219 <div align="justify">
220 <p style="text-align: justify;">
221
222 Treatment of primary and secondary bacterial infections of gastrointestinal, respiratory and genitourinary tracts, septicaemia caused by oxytetracycline-sensitive pathogens in poultry, large and small ruminants, swine, rodents, rabbits, fur-bearing animals and other animals. Some major indications are:
223
224 </p>
225 </div>
226
227
228
229
230
231
232
233
234
235
236
237
238 <div align="justify">
239 <p style="text-align: justify;">
240
241
242
243 </p>
244 </div>
245
246
247
248
249
250
251
252
253
254
255
256
257 <div align="justify">
258 <p style="text-align: justify;">
259
260 <i>Ruminants:</i>
261
262 </p>
263 </div>
264
265
266
267
268
269
270
271
272
273
274 <ul>
275 <li>
276
277 <div align="justify">
278 <p style="text-align: justify;">
279
280 <b><i>calves, lambs </i></b>in the<b><i> </i></b>pre-fattening period: prophylaxis of enteritis (<i>E. coli</i>); alleviation of stress condition.
281
282 </p>
283 </div>
284
285
286
287
288
289
290
291
292
293
294 <li>
295
296 <div align="justify">
297 <p style="text-align: justify;">
298
299 <b><i>steers </i></b>(over 160 kg of b. w.): prophylaxis of respiratory infections (infectious bovine rhinotracheitis, parainfluenza). Severe infections are treated with parenteral antibiotic, e. g. Geomycin<b><sup>®</sup></b><sup> </sup>retard.
300
301 </p>
302 </div>
303
304
305
306
307
308
309
310
311
312
313 </ul>
314
315 <div align="justify">
316 <p style="text-align: justify;">
317
318
319
320 </p>
321 </div>
322
323
324
325
326
327
328
329
330
331
332
333
334 <div align="justify">
335 <p style="text-align: justify;">
336
337 <i>Swine:</i>
338
339 </p>
340 </div>
341
342
343
344
345
346
347
348
349
350
351 <ul>
352 <li>
353
354 <div align="justify">
355 <p style="text-align: justify;">
356
357 <b><i>Piglets/suckling piglets</i></b> - decreasing the incidence of gastrointestinal disorders during weaning;
358
359 </p>
360 </div>
361
362
363
364
365
366
367
368
369
370
371 <li>
372
373 <div align="justify">
374 <p style="text-align: justify;">
375
376 <b><i>Suckling piglets/fattening pigs</i></b> - treatment of respiratory infections (enzootic bronchopneumonia, atrophic rhinitis); control of adverse effects of the stress in transportation and crowding; treatment of eperythrozoonosis, etc.
377
378 </p>
379 </div>
380
381
382
383
384
385
386
387
388
389
390 <li>
391
392 <div align="justify">
393 <p style="text-align: justify;">
394
395 <b><i>Sows/primiparous sows</i></b> - ante- and postpartum administration reduces excretion of the bacteria causing enteritis and controls mortality in piglets; prophylaxis of MMA syndrome; reduces the incidence of abortion and excretion of leptospira.
396
397 </p>
398 </div>
399
400
401
402
403
404
405
406
407
408
409 </ul>
410
411 <div align="justify">
412 <p style="text-align: justify;">
413
414
415
416 </p>
417 </div>
418
419
420
421
422
423
424
425
426
427
428
429
430 <div align="justify">
431 <p style="text-align: justify;">
432
433 <i>Poultry:</i>
434
435 </p>
436 </div>
437
438
439
440
441
442
443
444
445
446
447 <ul>
448 <li>
449
450 <div align="justify">
451 <p style="text-align: justify;">
452
453 <b><i>broilers and poults:</i></b> reduction of early deaths;
454
455 </p>
456 </div>
457
458
459
460
461
462
463
464
465
466
467 </ul><ul>
468 <li>
469
470 <div align="justify">
471 <p style="text-align: justify;">
472
473 chronic respiratory disease complex - CRD (<i>Mycoplasma gallisepticum</i> and <i>E. coli</i>), reduction of mortality and alleviation of clinical symptoms;
474
475 </p>
476 </div>
477
478
479
480
481
482
483
484
485
486
487 <li>
488
489 <div align="justify">
490 <p style="text-align: justify;">
491
492 treatment of cholera (<i>Pasteurella</i> <i>multocida</i>);
493
494 </p>
495 </div>
496
497
498
499
500
501
502
503
504
505
506 <li>
507
508 <div align="justify">
509 <p style="text-align: justify;">
510
511 prevention of diseases during stress conditions - change of housing, vaccination, extreme temperature variations, (e. g. chilling or overheating);
512
513 </p>
514 </div>
515
516
517
518
519
520
521
522
523
524
525 <li>
526
527 <div align="justify">
528 <p style="text-align: justify;">
529
530 hexamitiasis in turkeys (<i>Hexamita</i> <i>meleagridis</i>) and infectious sinovitis in turkeys (<i>Mycoplasma synoviae</i>);
531
532 </p>
533 </div>
534
535
536
537
538
539
540
541
542
543
544 <li>
545
546 <div align="justify">
547 <p style="text-align: justify;">
548
549 bacterial infections associated with blue comb (transmissive and coronaviral enteritis);
550
551 </p>
552 </div>
553
554
555
556
557
558
559
560
561
562
563 <li>
564
565 <div align="justify">
566 <p style="text-align: justify;">
567
568 respiratory infections in turkeys caused by <i>E. coli</i>,<i> Pasteurella</i> spp. and <i>Erysipelothrix insidiosa</i>.
569
570 </p>
571 </div>
572
573
574
575
576
577
578
579
580
581
582 </ul>
583
584 <div align="justify">
585 <p style="text-align: justify;">
586
587
588
589 </p>
590 </div>
591
592
593
594
595
596
597
598
599
600
601
602
603 <div align="justify">
604 <p style="text-align: justify;">
605
606 <b><i>Contraindications</i></b>
607
608 </p>
609 </div>
610
611
612
613
614
615
616
617
618
619
620
621
622 <div align="justify">
623 <p style="text-align: justify;">
624
625 Severe hepatic or renal impairment.
626
627 </p>
628 </div>
629
630
631
632
633
634
635
636
637
638
639
640
641 <div align="justify">
642 <p style="text-align: justify;">
643
644
645
646 </p>
647 </div>
648
649
650
651
652
653
654
655
656
657
658
659
660 <div align="justify">
661 <p style="text-align: justify;">
662
663 <b><i>Administration</i></b><b></b>
664
665 </p>
666 </div>
667
668
669
670
671
672
673
674
675
676
677
678
679 <div align="justify">
680 <p style="text-align: justify;">
681
682 Geomycin<b><sup>®</sup></b> powder is either dissolved in drinking water or given as a single dose dissolved in a small volume of water given by means of a sound. It can be given to some animals prior to meal, as top dressing (mixed priorly with a small portion of the ration). If given in drinking water, always prepare a fresh solution. Commonest duration of treatment is 3-5 days, which can be prolonged, if necessary.
683
684 </p>
685 </div>
686
687
688
689
690
691
692
693
694
695
696
697
698 <div align="justify">
699 <p style="text-align: justify;">
700
701
702
703 </p>
704 </div>
705
706
707
708
709
710
711
712
713
714
715
716
717 <div align="justify">
718 <p style="text-align: justify;">
719
720 <b><i>Dosage</i></b><b></b>
721
722 </p>
723 </div>
724
725
726
727
728
729
730
731
732
733
734
735
736 <div align="justify">
737 <p style="text-align: justify;">
738
739 One teaspoonful of 5 mL contains 3.0 g of powder or 165 mg of oxytetracycline hydrochloride.
740
741 </p>
742 </div>
743
744
745
746
747
748
749
750
751
752
753
754
755 <div align="justify">
756 <p style="text-align: justify;">
757
758 <i>Calves, lambs:</i> 1.5-2.5 teaspoonful of powder/45 kg of b. w. twice daily (≅10-20 mg of oxytetracycline hydrochloride/kg of b. w./day).
759
760 </p>
761 </div>
762
763
764
765
766
767
768
769
770
771
772
773
774 <div align="justify">
775 <p style="text-align: justify;">
776
777 <i>Cattle</i><b><i> </i></b><i>as functional ruminants</i><b><i>: </i></b>1 teaspoonful of powder/100 kg of b. w. twice daily (2-4 mg of oxytetracycline hydrochloride/kg of b. w./day).
778
779 </p>
780 </div>
781
782
783
784
785
786
787
788
789
790
791
792
793 <div align="justify">
794 <p style="text-align: justify;">
795
796 <i>Swine, rabbits, fur-bearing animals:</i> (chinchilla, mink): 1.5-4 teaspoonfuls of powder/20 kg of b. w. daily mixed with feed (10-30 mg of oxytetracycline hydrochloride/kg of b. w.) or dissolved in drinking water in the following ratios:
797
798 </p>
799 </div>
800
801
802
803
804
805
806
807
808
809
810
811
812 <div align="justify">
813 <p style="text-align: justify;">
814
815
816
817 </p>
818 </div>
819
820
821
822
823
824
825
826
827
828
829
830
831 <div align="justify">
832 <p style="text-align: justify;">
833
834
835
836 </p>
837 </div>
838
839
840
841
842
843
844
845
846 <table width="62.35%" border="1" cols="3" rows="6">
847 <tr>
848 <td bgcolor="White" width="100.00%" rowspan="1" colspan="3">
849
850 <div align="center">
851 <p style="text-align: center;">
852
853 Oxytetracycline hydrochloride levels
854
855 </p>
856 </div>
857
858
859
860
861 </td>
862
863
864
865
866
867
868
869 </tr>
870
871
872
873 <tr>
874 <td bgcolor="White" width="45.21%" rowspan="1" colspan="1">
875
876 <div align="left">
877 <p style="text-align: left;">
878
879
880
881 </p>
882 </div>
883
884
885
886
887 </td>
888
889
890
891
892
893 <td bgcolor="White" width="25.86%" rowspan="1" colspan="1">
894
895 <div align="left">
896 <p style="text-align: left;">
897
898 88 mg/L
899
900 </p>
901 </div>
902
903
904
905
906 </td>
907
908
909
910
911
912 <td bgcolor="White" width="28.93%" rowspan="1" colspan="1">
913
914 <div align="left">
915 <p style="text-align: left;">
916
917 275 mg/L
918
919 </p>
920 </div>
921
922
923
924
925 </td>
926
927
928
929
930
931
932
933 </tr>
934
935
936
937 <tr>
938 <td bgcolor="White" width="45.21%" rowspan="1" colspan="1">
939
940 <div align="left">
941 <p style="text-align: left;">
942
943 Geomycin<b><sup>®</sup></b> 5.5% powder
944
945 </p>
946 </div>
947
948
949
950
951 </td>
952
953
954
955
956
957 <td bgcolor="White" width="25.86%" rowspan="1" colspan="1">
958
959 <div align="left">
960 <p style="text-align: left;">
961
962 water
963
964 </p>
965 </div>
966
967
968
969
970 </td>
971
972
973
974
975
976 <td bgcolor="White" width="28.93%" rowspan="1" colspan="1">
977
978 <div align="left">
979 <p style="text-align: left;">
980
981 water
982
983 </p>
984 </div>
985
986
987
988
989 </td>
990
991
992
993
994
995
996
997 </tr>
998
999
1000
1001 <tr>
1002 <td bgcolor="White" width="45.21%" rowspan="1" colspan="1">
1003
1004 <div align="left">
1005 <p style="text-align: left;">
1006
1007 1 teaspoonful
1008
1009 </p>
1010 </div>
1011
1012
1013
1014
1015
1016
1017
1018
1019
1020
1021
1022
1023 <div align="left">
1024 <p style="text-align: left;">
1025
1026 (3 g)
1027
1028 </p>
1029 </div>
1030
1031
1032
1033
1034 </td>
1035
1036
1037
1038
1039
1040 <td bgcolor="White" width="25.86%" rowspan="1" colspan="1">
1041
1042 <div align="left">
1043 <p style="text-align: left;">
1044
1045 1.8 L
1046
1047 </p>
1048 </div>
1049
1050
1051
1052
1053 </td>
1054
1055
1056
1057
1058
1059 <td bgcolor="White" width="28.93%" rowspan="1" colspan="1">
1060
1061 <div align="left">
1062 <p style="text-align: left;">
1063
1064 0.6 L
1065
1066 </p>
1067 </div>
1068
1069
1070
1071
1072 </td>
1073
1074
1075
1076
1077
1078
1079
1080 </tr>
1081
1082
1083
1084 <tr>
1085 <td bgcolor="White" width="45.21%" rowspan="1" colspan="1">
1086
1087 <div align="left">
1088 <p style="text-align: left;">
1089
1090 100 g
1091
1092 </p>
1093 </div>
1094
1095
1096
1097
1098 </td>
1099
1100
1101
1102
1103
1104 <td bgcolor="White" width="25.86%" rowspan="1" colspan="1">
1105
1106 <div align="left">
1107 <p style="text-align: left;">
1108
1109 62.5 L
1110
1111 </p>
1112 </div>
1113
1114
1115
1116
1117 </td>
1118
1119
1120
1121
1122
1123 <td bgcolor="White" width="28.93%" rowspan="1" colspan="1">
1124
1125 <div align="left">
1126 <p style="text-align: left;">
1127
1128 20.0 L
1129
1130 </p>
1131 </div>
1132
1133
1134
1135
1136 </td>
1137
1138
1139
1140
1141
1142
1143
1144 </tr>
1145
1146
1147
1148 <tr>
1149 <td bgcolor="White" width="45.21%" rowspan="1" colspan="1">
1150
1151 <div align="left">
1152 <p style="text-align: left;">
1153
1154 150 g
1155
1156 </p>
1157 </div>
1158
1159
1160
1161
1162 </td>
1163
1164
1165
1166
1167
1168 <td bgcolor="White" width="25.86%" rowspan="1" colspan="1">
1169
1170 <div align="left">
1171 <p style="text-align: left;">
1172
1173 94.0 L
1174
1175 </p>
1176 </div>
1177
1178
1179
1180
1181 </td>
1182
1183
1184
1185
1186
1187 <td bgcolor="White" width="28.93%" rowspan="1" colspan="1">
1188
1189 <div align="left">
1190 <p style="text-align: left;">
1191
1192 30.0 L
1193
1194 </p>
1195 </div>
1196
1197
1198
1199
1200 </td>
1201
1202
1203
1204
1205
1206
1207
1208 </tr>
1209
1210 </table>
1211
1212
1213
1214
1215 <div align="justify">
1216 <p style="text-align: justify;">
1217
1218
1219
1220 </p>
1221 </div>
1222
1223
1224
1225
1226
1227
1228
1229
1230
1231
1232
1233
1234 <div align="justify">
1235 <p style="text-align: justify;">
1236
1237 If given to swine with feed, add to 10 kg of feed 20-50 g of Geomycin<b><sup>®</sup></b><sup> </sup>5.5% powder (110-275 ppm of oxytetracycline hydrochloride).
1238
1239 </p>
1240 </div>
1241
1242
1243
1244
1245
1246
1247
1248
1249
1250
1251
1252
1253 <div align="justify">
1254 <p style="text-align: justify;">
1255
1256
1257
1258 </p>
1259 </div>
1260
1261
1262
1263
1264
1265
1266
1267
1268
1269
1270
1271
1272 <div align="justify">
1273 <p style="text-align: justify;">
1274
1275 <i>Chicks and poults:</i> Relevant to severity of the infection, Geomycin<b><sup>®</sup></b> 5.5% soluble powder is given in the concentration of 66-264 mg/L.
1276
1277 </p>
1278 </div>
1279
1280
1281
1282
1283
1284
1285
1286
1287
1288
1289
1290
1291 <div align="justify">
1292 <p style="text-align: justify;">
1293
1294
1295
1296 </p>
1297 </div>
1298
1299
1300
1301
1302
1303
1304
1305
1306
1307
1308
1309
1310 <div align="justify">
1311 <p style="text-align: justify;">
1312
1313
1314
1315 </p>
1316 </div>
1317
1318
1319
1320
1321
1322
1323
1324
1325 <table width="61.46%" border="1" cols="3" rows="6">
1326 <tr>
1327 <td bgcolor="White" width="100.00%" rowspan="1" colspan="3">
1328
1329 <div align="center">
1330 <p style="text-align: center;">
1331
1332 Oxytetracycline hydrochloride
1333
1334 </p>
1335 </div>
1336
1337
1338
1339
1340
1341
1342
1343
1344
1345
1346
1347
1348 <div align="center">
1349 <p style="text-align: center;">
1350
1351 levels
1352
1353 </p>
1354 </div>
1355
1356
1357
1358
1359 </td>
1360
1361
1362
1363
1364
1365
1366
1367 </tr>
1368
1369
1370
1371 <tr>
1372 <td bgcolor="White" width="45.86%" rowspan="1" colspan="1">
1373
1374 <div align="justify">
1375 <p style="text-align: justify;">
1376
1377
1378
1379 </p>
1380 </div>
1381
1382
1383
1384
1385 </td>
1386
1387
1388
1389
1390
1391 <td bgcolor="White" width="26.23%" rowspan="1" colspan="1">
1392
1393 <div align="center">
1394 <p style="text-align: center;">
1395
1396 66 mg/L
1397
1398 </p>
1399 </div>
1400
1401
1402
1403
1404 </td>
1405
1406
1407
1408
1409
1410 <td bgcolor="White" width="27.91%" rowspan="1" colspan="1">
1411
1412 <div align="center">
1413 <p style="text-align: center;">
1414
1415 264 mg/L
1416
1417 </p>
1418 </div>
1419
1420
1421
1422
1423 </td>
1424
1425
1426
1427
1428
1429
1430
1431 </tr>
1432
1433
1434
1435 <tr>
1436 <td bgcolor="White" width="45.86%" rowspan="1" colspan="1">
1437
1438 <div align="left">
1439 <p style="text-align: left;">
1440
1441 Geomycin<b><sup>®</sup></b> 5.5% powder
1442
1443 </p>
1444 </div>
1445
1446
1447
1448
1449 </td>
1450
1451
1452
1453
1454
1455 <td bgcolor="White" width="26.23%" rowspan="1" colspan="1">
1456
1457 <div align="left">
1458 <p style="text-align: left;">
1459
1460 water
1461
1462 </p>
1463 </div>
1464
1465
1466
1467
1468 </td>
1469
1470
1471
1472
1473
1474 <td bgcolor="White" width="27.91%" rowspan="1" colspan="1">
1475
1476 <div align="left">
1477 <p style="text-align: left;">
1478
1479 water
1480
1481 </p>
1482 </div>
1483
1484
1485
1486
1487 </td>
1488
1489
1490
1491
1492
1493
1494
1495 </tr>
1496
1497
1498
1499 <tr>
1500 <td bgcolor="White" width="45.86%" rowspan="1" colspan="1">
1501
1502 <div align="left">
1503 <p style="text-align: left;">
1504
1505 1 teaspoonful
1506
1507 </p>
1508 </div>
1509
1510
1511
1512
1513
1514
1515
1516
1517
1518
1519
1520
1521 <div align="left">
1522 <p style="text-align: left;">
1523
1524 (3 g)
1525
1526 </p>
1527 </div>
1528
1529
1530
1531
1532 </td>
1533
1534
1535
1536
1537
1538 <td bgcolor="White" width="26.23%" rowspan="1" colspan="1">
1539
1540 <div align="left">
1541 <p style="text-align: left;">
1542
1543 2.3 L
1544
1545 </p>
1546 </div>
1547
1548
1549
1550
1551 </td>
1552
1553
1554
1555
1556
1557 <td bgcolor="White" width="27.91%" rowspan="1" colspan="1">
1558
1559 <div align="left">
1560 <p style="text-align: left;">
1561
1562 0.6 L
1563
1564 </p>
1565 </div>
1566
1567
1568
1569
1570 </td>
1571
1572
1573
1574
1575
1576
1577
1578 </tr>
1579
1580
1581
1582 <tr>
1583 <td bgcolor="White" width="45.86%" rowspan="1" colspan="1">
1584
1585 <div align="left">
1586 <p style="text-align: left;">
1587
1588 100 g
1589
1590 </p>
1591 </div>
1592
1593
1594
1595
1596 </td>
1597
1598
1599
1600
1601
1602 <td bgcolor="White" width="26.23%" rowspan="1" colspan="1">
1603
1604 <div align="left">
1605 <p style="text-align: left;">
1606
1607 83 L
1608
1609 </p>
1610 </div>
1611
1612
1613
1614
1615 </td>
1616
1617
1618
1619
1620
1621 <td bgcolor="White" width="27.91%" rowspan="1" colspan="1">
1622
1623 <div align="left">
1624 <p style="text-align: left;">
1625
1626 21 L
1627
1628 </p>
1629 </div>
1630
1631
1632
1633
1634 </td>
1635
1636
1637
1638
1639
1640
1641
1642 </tr>
1643
1644
1645
1646 <tr>
1647 <td bgcolor="White" width="45.86%" rowspan="1" colspan="1">
1648
1649 <div align="left">
1650 <p style="text-align: left;">
1651
1652 150 g
1653
1654 </p>
1655 </div>
1656
1657
1658
1659
1660 </td>
1661
1662
1663
1664
1665
1666 <td bgcolor="White" width="26.23%" rowspan="1" colspan="1">
1667
1668 <div align="left">
1669 <p style="text-align: left;">
1670
1671 125 L
1672
1673 </p>
1674 </div>
1675
1676
1677
1678
1679 </td>
1680
1681
1682
1683
1684
1685 <td bgcolor="White" width="27.91%" rowspan="1" colspan="1">
1686
1687 <div align="left">
1688 <p style="text-align: left;">
1689
1690 31 L
1691
1692 </p>
1693 </div>
1694
1695
1696
1697
1698 </td>
1699
1700
1701
1702
1703
1704
1705
1706 </tr>
1707
1708 </table>
1709
1710
1711
1712
1713 <div align="justify">
1714 <p style="text-align: justify;">
1715
1716
1717
1718 </p>
1719 </div>
1720
1721
1722
1723
1724
1725
1726
1727
1728
1729
1730
1731
1732 <div align="justify">
1733 <p style="text-align: justify;">
1734
1735 In severe infections, the above levels of oxytetracycline hydrochloride in drinking water may be increased.
1736
1737 </p>
1738 </div>
1739
1740
1741
1742
1743
1744
1745
1746
1747
1748
1749
1750
1751 <div align="justify">
1752 <p style="text-align: justify;">
1753
1754
1755
1756 </p>
1757 </div>
1758
1759
1760
1761
1762
1763
1764
1765
1766
1767
1768
1769
1770 <div align="justify">
1771 <p style="text-align: justify;">
1772
1773 <b><i>Warnings and precautions</i></b>
1774
1775 </p>
1776 </div>
1777
1778
1779
1780
1781
1782
1783
1784
1785
1786
1787
1788
1789 <div align="justify">
1790 <p style="text-align: justify;">
1791
1792 Prepare a fresh solution every day and ensure that it is the only source of drinking water. The powder should be completely dissolved.
1793
1794 </p>
1795 </div>
1796
1797
1798
1799
1800
1801
1802
1803
1804
1805
1806
1807
1808 <div align="justify">
1809 <p style="text-align: justify;">
1810
1811
1812
1813 </p>
1814 </div>
1815
1816
1817
1818
1819
1820
1821
1822
1823
1824
1825
1826
1827 <div align="justify">
1828 <p style="text-align: justify;">
1829
1830 It is inadvisable to give Geomycin<b><sup>®</sup></b> 5.5% powder in the slops, milk, milk supplements or silage.
1831
1832 </p>
1833 </div>
1834
1835
1836
1837
1838
1839
1840
1841
1842
1843
1844
1845
1846 <div align="justify">
1847 <p style="text-align: justify;">
1848
1849
1850
1851 </p>
1852 </div>
1853
1854
1855
1856
1857
1858
1859
1860
1861
1862
1863
1864
1865 <div align="justify">
1866 <p style="text-align: justify;">
1867
1868 During treatment it is recommended that the feed has low mineral content, because in combination with bi- and trivalent cations (Ca, Mg, Fe) oxytetracycline creates microbiologically ineffective chelates.
1869
1870 </p>
1871 </div>
1872
1873
1874
1875
1876
1877
1878
1879
1880
1881
1882
1883
1884 <div align="justify">
1885 <p style="text-align: justify;">
1886
1887
1888
1889 </p>
1890 </div>
1891
1892
1893
1894
1895
1896
1897
1898
1899
1900
1901
1902
1903 <div align="justify">
1904 <p style="text-align: justify;">
1905
1906 Concurrent administration of oxytetracycline and beta-lactam and/or aminoglycoside antibiotics is not recommended.
1907
1908 </p>
1909 </div>
1910
1911
1912
1913
1914
1915
1916
1917
1918
1919
1920
1921
1922 <div align="justify">
1923 <p style="text-align: justify;">
1924
1925
1926
1927 </p>
1928 </div>
1929
1930
1931
1932
1933
1934
1935
1936
1937
1938
1939
1940
1941 <div align="justify">
1942 <p style="text-align: justify;">
1943
1944 If the animals fail to respond to treatment 2-3 days from its onset, check the diagnosis and perform sensitivity tests for oxytetracycline.
1945
1946 </p>
1947 </div>
1948
1949
1950
1951
1952
1953
1954
1955
1956
1957
1958
1959
1960 <div align="justify">
1961 <p style="text-align: justify;">
1962
1963
1964
1965 </p>
1966 </div>
1967
1968
1969
1970
1971
1972
1973
1974
1975
1976
1977
1978
1979 <div align="justify">
1980 <p style="text-align: justify;">
1981
1982 In adult ruminants oral administration of oxytetracycline may cause transient misbalance of the forestomach microflora and slightly interfere with disintegration of cellulose.
1983
1984 </p>
1985 </div>
1986
1987
1988
1989
1990
1991
1992
1993
1994
1995
1996
1997
1998 <div align="justify">
1999 <p style="text-align: justify;">
2000
2001
2002
2003 </p>
2004 </div>
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017 <div align="justify">
2018 <p style="text-align: justify;">
2019
2020 <b><i>Withdrawal</i></b>
2021
2022 </p>
2023 </div>
2024
2025
2026
2027
2028
2029
2030
2031
2032
2033
2034
2035
2036 <div align="justify">
2037 <p style="text-align: justify;">
2038
2039 Meat - calves, lambs, kids 10 days
2040
2041 </p>
2042 </div>
2043
2044
2045
2046
2047
2048
2049
2050
2051
2052
2053
2054
2055 <div align="justify">
2056 <p style="text-align: justify;">
2057
2058 Meat - broilers, poult, swine 7 days
2059
2060 </p>
2061 </div>
2062
2063
2064
2065
2066
2067
2068
2069
2070
2071
2072
2073
2074 <div align="justify">
2075 <p style="text-align: justify;">
2076
2077 Eggs 1 day
2078
2079 </p>
2080 </div>
2081
2082
2083
2084
2085
2086
2087
2088
2089
2090
2091
2092
2093 <div align="justify">
2094 <p style="text-align: justify;">
2095
2096
2097
2098 </p>
2099 </div>
2100
2101
2102
2103
2104
2105
2106
2107
2108
2109
2110
2111
2112 <div align="justify">
2113 <p style="text-align: justify;">
2114
2115 <b><i>Storage</i></b>
2116
2117 </p>
2118 </div>
2119
2120
2121
2122
2123
2124
2125
2126
2127
2128
2129
2130
2131 <div align="justify">
2132 <p style="text-align: justify;">
2133
2134 Store in a dry place at controlled room temperature (up to 258C). Keep away from children.
2135
2136 </p>
2137 </div>
2138
2139
2140
2141
2142
2143
2144
2145
2146
2147
2148
2149
2150 <div align="justify">
2151 <p style="text-align: justify;">
2152
2153
2154
2155 </p>
2156 </div>
2157
2158
2159
2160
2161
2162
2163
2164
2165
2166
2167
2168
2169 <div align="justify">
2170 <p style="text-align: justify;">
2171
2172 <b><i>Shelf life</i></b>
2173
2174 </p>
2175 </div>
2176
2177
2178
2179
2180
2181
2182
2183
2184
2185
2186
2187
2188 <div align="justify">
2189 <p style="text-align: justify;">
2190
2191 Denoted on the packaging<b> </b>(5 years in the original pack).
2192
2193 </p>
2194 </div>
2195
2196
2197
2198
2199
2200
2201
2202
2203
2204
2205
2206
2207 <div align="justify">
2208 <p style="text-align: justify;">
2209
2210 <b></b>
2211
2212 </p>
2213 </div>
2214
2215
2216
2217
2218
2219
2220
2221
2222
2223
2224
2225
2226 <div align="justify">
2227 <p style="text-align: justify;">
2228
2229 <b><i>Legal category</i></b>
2230
2231 </p>
2232 </div>
2233
2234
2235
2236
2237
2238
2239
2240
2241
2242
2243
2244
2245 <div align="justify">
2246 <p style="text-align: justify;">
2247
2248 On prescription only.
2249
2250 </p>
2251 </div>
2252
2253
2254
2255
2256
2257
2258
2259
2260
2261
2262
2263
2264 <div align="justify">
2265 <p style="text-align: justify;">
2266
2267
2268
2269 </p>
2270 </div>
2271
2272
2273
2274
2275
2276
2277
2278
2279
2280
2281
2282
2283 <div align="justify">
2284 <p style="text-align: justify;">
2285
2286 <b><i>Supply</i></b>
2287
2288 </p>
2289 </div>
2290
2291
2292
2293
2294
2295
2296
2297
2298
2299
2300
2301
2302 <div align="justify">
2303 <p style="text-align: justify;">
2304
2305 Bottles with 100 g, 200 g and 1000 g
2306
2307 </p>
2308 </div>
2309
2310
2311
2312
2313
2314
2315
2316
2317
2318
2319
2320
2321 <div align="justify">
2322 <p style="text-align: justify;">
2323
2324 Alu-sachets with 150 g.
2325
2326 </p>
2327 </div>
2328
2329
2330
2331
2332
2333
2334
2335
2336
2337
2338
2339
2340 <div align="justify">
2341 <p style="text-align: justify;">
2342
2343
2344
2345 </p>
2346 </div>
2347
2348
2349
2350
2351
2352
2353
2354
2355
2356
2357
2358
2359 <div align="justify">
2360 <p style="text-align: justify;">
2361
2362 <b><i>Manufacturer</i></b><b></b>
2363
2364 </p>
2365 </div>
2366
2367
2368
2369
2370
2371
2372
2373
2374
2375
2376
2377
2378 <div align="justify">
2379 <p style="text-align: justify;">
2380
2381 VETERINA Animal Health Ltd., Croatia
2382
2383 </p>
2384 </div>
2385
2386
2387
2388
2389
2390
2391
2392
2393
2394
2395
2396
2397 <div align="justify">
2398 <p style="text-align: justify;">
2399
2400
2401
2402 </p>
2403 </div>
2404
2405
2406
2407
2408
2409
2410
2411
2412
2413
2414
2415
2416 <div align="justify">
2417 <p style="text-align: justify;">
2418
2419
2420
2421 </p>
2422 </div>
2423
2424
2425
2426
2427
2428
2429
2430
2431
2432
2433
2434
2435 <div align="left">
2436 <p style="text-align: left;">
2437
2438
2439
2440 </p>
2441 </div>
2442
2443
2444
2445
2446
2447
2448
2449 <!--Section Ends-->
2450
2451
2452
2453
2454
2455
2456
2457

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