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<!--Section Begins--><br> |
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<div align="left"> |
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<p style="text-align: left;"> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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<b>AMPIVET</b><b><sup>® </sup></b><b>K</b> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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suspension for intramammary administration against mastitis in the lactating cows |
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</p> |
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</div> |
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<div align="justify"> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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<b><i>Composition</i></b> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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5 mL contain: |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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Cloxacillin as cloxacillin sodium 100 mg |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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Ampicillin as ampicillin trihydrate 200 mg |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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Base - white paraffin and liquid paraffin up to 5 mL |
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</p> |
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</div> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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<b><i>Action</i></b> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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AMPIVET<sup>® </sup>K is a combination of semi-synthetic penicillins (ampicillin and cloxacillin) which inhibit cross-linking of peptoglycan threads and act bactericidally on the growing bacteria. It has antimicrobial action against major gram-positive and gram-negative pathogens: <i>Streptococcus agalactiae, Streptococcus dysgalactiae, Streptococcus uberis, Staphylococcus aureus, E. coli, Actinomyces pyogenes</i>, etc. Both penicillin ingredients exert an additive and partially synergistic effect. Given the resistance of bacterial beta-lactamase to cloxacillin, AMPIVET<sup>® </sup>K successfully treats inflammations caused by benzylpenicillin-resistant strains of staphylococci. Intramammary infusion has batericidal effect and does not cause local tissue irritation. The treatment should be long enough to achieve clinical cure. |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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<b><i>Indications</i></b> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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Treatment of lactating cows against clinical and subclinical mastitis caused by ampicillin- and cloxacillin-sensitive gram-positive and gram-negative bacteria. AMPIVET<sup>® </sup>K is particularly indicated against udder inflammations caused by streptococci, staphylococci, <i>E. coli</i> and <i>Actinomyces pyogenes </i>species. |
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</p> |
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</div> |
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</div> |
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<p style="text-align: justify;"> |
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<b><i>Contraindications</i></b> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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AMPIVET<sup>® </sup>K should not be given to the cows during dry period. |
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</p> |
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</div> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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<b><i>Administration and dosage</i></b> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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Immediately prior to administration of AMPIVET<sup>® </sup>K milk out the udder. Teat ends and orifices must be clean and disinfected. Introduce the tip of the injector into the beginning of the teat canal and slowly inject the contents. |
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</p> |
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</div> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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After administration of AMPIVET<sup>® </sup>K gently massage the udder upward, from the teat to the udder base, to evenly distribute the drug over the milk cistern, through the canals and alveoli of the mammary gland. |
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</p> |
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</div> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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Inject the contents of one injector into each affected quarter in 12- hour intervals. Milk out the udder before each administration. |
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</p> |
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</div> |
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</p> |
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<p style="text-align: justify;"> |
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<b><i>Warnings, precautions and interactions</i></b> |
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</p> |
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</div> |
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<p style="text-align: justify;"> |
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Manifestations of allergic reactions in the animals hypersensitive to penicillin antibiotics have been reported extremely rarely. Concurrent intramammary infusion of penicillins with systemic tetracycline or macrolide antibiotics is not recommended. |
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</p> |
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</div> |
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</div> |
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If more animals in a herd are affected, it is recommended to perform sensitivity tests before the treatment. |
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</p> |
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</div> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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After removal of the protective cap, care should be taken not to contaminate tip of the injector. |
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</p> |
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</div> |
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</p> |
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</div> |
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<p style="text-align: justify;"> |
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<b><i>Withdrawal</i></b> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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Meat, organs and other edible tissues - 0 days. |
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</p> |
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</div> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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Milk - 3 days. Milk of the cows that are milked twice daily can be used after the sixth milking. |
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</p> |
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</div> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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<b><i>Storage</i></b> |
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</p> |
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</div> |
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<p style="text-align: justify;"> |
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Store in a cool place up to 15ËC. Keep away from children. Avoid freezing. |
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</p> |
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</div> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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<b><i>Shelf life</i></b> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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Denoted on the packaging (2 years). |
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</p> |
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</div> |
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<div align="justify"> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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<b><i>Legal category</i></b> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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On prescription only. |
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</p> |
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</div> |
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<div align="justify"> |
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</p> |
890 |
</div> |
891 |
|
892 |
|
893 |
|
894 |
|
895 |
|
896 |
|
897 |
|
898 |
|
899 |
|
900 |
|
901 |
|
902 |
|
903 |
<div align="justify"> |
904 |
<p style="text-align: justify;"> |
905 |
|
906 |
<b><i>Supply</i></b> |
907 |
|
908 |
</p> |
909 |
</div> |
910 |
|
911 |
|
912 |
|
913 |
|
914 |
|
915 |
|
916 |
|
917 |
|
918 |
|
919 |
|
920 |
|
921 |
|
922 |
<div align="justify"> |
923 |
<p style="text-align: justify;"> |
924 |
|
925 |
Box with 12 injectors of 5 mL. |
926 |
|
927 |
</p> |
928 |
</div> |
929 |
|
930 |
|
931 |
|
932 |
|
933 |
|
934 |
|
935 |
|
936 |
|
937 |
|
938 |
|
939 |
|
940 |
|
941 |
<div align="justify"> |
942 |
<p style="text-align: justify;"> |
943 |
|
944 |
|
945 |
|
946 |
</p> |
947 |
</div> |
948 |
|
949 |
|
950 |
|
951 |
|
952 |
|
953 |
|
954 |
|
955 |
|
956 |
|
957 |
|
958 |
|
959 |
|
960 |
<div align="justify"> |
961 |
<p style="text-align: justify;"> |
962 |
|
963 |
<b><i>Manufacturer</i></b> |
964 |
|
965 |
</p> |
966 |
</div> |
967 |
|
968 |
|
969 |
|
970 |
|
971 |
|
972 |
|
973 |
|
974 |
|
975 |
|
976 |
|
977 |
|
978 |
|
979 |
<div align="justify"> |
980 |
<p style="text-align: justify;"> |
981 |
|
982 |
VETERINA Animal Health Ltd., Croatia |
983 |
|
984 |
</p> |
985 |
</div> |
986 |
|
987 |
|
988 |
|
989 |
|
990 |
|
991 |
|
992 |
|
993 |
|
994 |
|
995 |
|
996 |
|
997 |
|
998 |
<div align="left"> |
999 |
<p style="text-align: left;"> |
1000 |
|
1001 |
|
1002 |
|
1003 |
</p> |
1004 |
</div> |
1005 |
|
1006 |
|
1007 |
|
1008 |
|
1009 |
|
1010 |
|
1011 |
|
1012 |
|
1013 |
|
1014 |
|
1015 |
|
1016 |
|
1017 |
<div align="left"> |
1018 |
<p style="text-align: left;"> |
1019 |
|
1020 |
|
1021 |
|
1022 |
</p> |
1023 |
</div> |
1024 |
|
1025 |
|
1026 |
|
1027 |
|
1028 |
|
1029 |
|
1030 |
|
1031 |
<!--Section Ends--> |
1032 |
|
1033 |
|
1034 |
|
1035 |
|
1036 |
|
1037 |
|
1038 |
|
1039 |
|