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Tue Apr 10 11:02:10 2001 UTC (18 years, 3 months ago) by dpavlin
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3 <!--Section Begins--><br>
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10 <div align="justify">
11 <p style="text-align: justify;">
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15 </p>
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29 <div align="justify">
30 <p style="text-align: justify;">
31
32 <b>GUMBOKAL</b><b><sup>®</sup></b>
33
34 </p>
35 </div>
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48 <div align="justify">
49 <p style="text-align: justify;">
50
51 <i>inactivated oily vaccine against Gumboro disease</i>
52
53 </p>
54 </div>
55
56
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67 <div align="justify">
68 <p style="text-align: justify;">
69
70 <b></b>
71
72 </p>
73 </div>
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86 <div align="justify">
87 <p style="text-align: justify;">
88
89 <b><i>Composition</i></b><b></b>
90
91 </p>
92 </div>
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105 <div align="justify">
106 <p style="text-align: justify;">
107
108 The vaccine contains inactivated Gumboro disease virus grown in embryonated chicks' eggs, inactivated with formaldehyde and re-suspended, with the addition of an emulsifier, in mineral oil as a multiple emulsion water/oil/water type.
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110 </p>
111 </div>
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122
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124 <div align="justify">
125 <p style="text-align: justify;">
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129 </p>
130 </div>
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141
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143 <div align="justify">
144 <p style="text-align: justify;">
145
146 <b><i>Action</i></b><b></b>
147
148 </p>
149 </div>
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162 <div align="justify">
163 <p style="text-align: justify;">
164
165 The vaccine stimulates formation of the specific antibodies for Gumboro disease virus.
166
167 </p>
168 </div>
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181 <div align="justify">
182 <p style="text-align: justify;">
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186 </p>
187 </div>
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200 <div align="justify">
201 <p style="text-align: justify;">
202
203 <b><i>Indications</i></b>
204
205 </p>
206 </div>
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219 <div align="justify">
220 <p style="text-align: justify;">
221
222 Immunoprophylaxis of healthy hybrids of light and heavy breeds against infectious bursal disease (Gumboro disease) and immunisation of their offspring during their first 2-4 weeks of life.
223
224 </p>
225 </div>
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236
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238 <div align="justify">
239 <p style="text-align: justify;">
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243 </p>
244 </div>
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257 <div align="justify">
258 <p style="text-align: justify;">
259
260 <b><i>Contraindications</i></b>
261
262 </p>
263 </div>
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276 <div align="justify">
277 <p style="text-align: justify;">
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279 Unknown.
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281 </p>
282 </div>
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295 <div align="justify">
296 <p style="text-align: justify;">
297
298 <b><i></i></b>
299
300 </p>
301 </div>
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311
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314 <div align="justify">
315 <p style="text-align: justify;">
316
317 Administration, dosage and vaccination programme<b></b>
318
319 </p>
320 </div>
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329
330
331
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333 <div align="justify">
334 <p style="text-align: justify;">
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336 GUMBOKAL<b><sup>®</sup></b> is given by i. m<i>.</i> route into the breast muscle or s. c. into the skin fold at the dorsal neck side. The dose per bird is 0.5 mL. Before administration the vaccine should be heated to room temperature and shaken well prior to and occasionally during administration.
337
338 </p>
339 </div>
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352 <div align="justify">
353 <p style="text-align: justify;">
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357 </p>
358 </div>
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371 <div align="justify">
372 <p style="text-align: justify;">
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374 As a rule, the birds are vaccinated at the age of 16-20 weeks.
375
376 </p>
377 </div>
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390 <div align="justify">
391 <p style="text-align: justify;">
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395 </p>
396 </div>
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409 <div align="justify">
410 <p style="text-align: justify;">
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412 Before being vaccinated with GUMBOKAL<b><sup>®</sup></b> the chicks should be given live vaccine against Gumboro disease. Time between these two vaccinations should not be shorter than 2 weeks. Optimum effect is achieved with an interval of 6 weeks.
413
414 </p>
415 </div>
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428 <div align="justify">
429 <p style="text-align: justify;">
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433 </p>
434 </div>
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447 <div align="justify">
448 <p style="text-align: justify;">
449
450 <b><i>Immunity</i></b>
451
452 </p>
453 </div>
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460
461
462
463
464
465
466 <div align="justify">
467 <p style="text-align: justify;">
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469 In healthy chicks the immunity is established 2-3 weeks after vaccination and is maintained till the end of the production cycle. This ensures the immunity of their offspring against infectious bursal disease during their first 2-4 weeks of life.
470
471 </p>
472 </div>
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485 <div align="justify">
486 <p style="text-align: justify;">
487
488 <b></b>
489
490 </p>
491 </div>
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502
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504 <div align="justify">
505 <p style="text-align: justify;">
506
507 <b><i>Warnings and precautions</i></b><b></b>
508
509 </p>
510 </div>
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521
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523 <div align="justify">
524 <p style="text-align: justify;">
525
526 The vaccine is administered to all birds in the flock.
527
528 </p>
529 </div>
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542 <div align="justify">
543 <p style="text-align: justify;">
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547 </p>
548 </div>
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561 <div align="justify">
562 <p style="text-align: justify;">
563
564 Once opened use within 24 hours.
565
566 </p>
567 </div>
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577
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580 <div align="justify">
581 <p style="text-align: justify;">
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585 </p>
586 </div>
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599 <div align="justify">
600 <p style="text-align: justify;">
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602 Packaging and vaccine leftovers must be disposed in a safe way.
603
604 </p>
605 </div>
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618 <div align="justify">
619 <p style="text-align: justify;">
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623 </p>
624 </div>
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637 <div align="justify">
638 <p style="text-align: justify;">
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640 Avoid direct exposure to sunlight and high temperatures.
641
642 </p>
643 </div>
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656 <div align="justify">
657 <p style="text-align: justify;">
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661 </p>
662 </div>
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675 <div align="justify">
676 <p style="text-align: justify;">
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678 Beware of accidental injecting into the hand. In severe local reaction seek medical advice (surgeon).
679
680 </p>
681 </div>
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694 <div align="justify">
695 <p style="text-align: justify;">
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699 </p>
700 </div>
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713 <div align="justify">
714 <p style="text-align: justify;">
715
716 <b><i>Withdrawal</i></b>
717
718 </p>
719 </div>
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732 <div align="justify">
733 <p style="text-align: justify;">
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735 Meat, organs and other edible tissues of the vaccinated pullets - 0 days.
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737 </p>
738 </div>
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751 <div align="justify">
752 <p style="text-align: justify;">
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754 <b></b>
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756 </p>
757 </div>
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770 <div align="justify">
771 <p style="text-align: justify;">
772
773 <b><i>Storage</i></b>
774
775 </p>
776 </div>
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789 <div align="justify">
790 <p style="text-align: justify;">
791
792 Store in a dark place at 2-8°C (refrigerator). Keep away from children. Avoid freezing.
793
794 </p>
795 </div>
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808 <div align="justify">
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813 </p>
814 </div>
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827 <div align="justify">
828 <p style="text-align: justify;">
829
830 <b><i>Shelf life</i></b><b></b>
831
832 </p>
833 </div>
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846 <div align="justify">
847 <p style="text-align: justify;">
848
849 Denoted on the packaging (18 months in the original pack).
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851 </p>
852 </div>
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865 <div align="justify">
866 <p style="text-align: justify;">
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870 </p>
871 </div>
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884 <div align="justify">
885 <p style="text-align: justify;">
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887 <b><i>Legal category</i></b><b></b>
888
889 </p>
890 </div>
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901
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903 <div align="justify">
904 <p style="text-align: justify;">
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906 On prescription only.
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908 </p>
909 </div>
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923 <p style="text-align: justify;">
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928 </div>
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941 <div align="justify">
942 <p style="text-align: justify;">
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944 <b><i>Supply</i></b><b></b>
945
946 </p>
947 </div>
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960 <div align="justify">
961 <p style="text-align: justify;">
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963 Pierced bottle of 100 mL (200 doses) and 500 mL (1000 doses).
964
965 </p>
966 </div>
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984 </p>
985 </div>
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998 <div align="justify">
999 <p style="text-align: justify;">
1000
1001 <b><i>Manufacturer</i></b><b></b>
1002
1003 </p>
1004 </div>
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1020 VETERINA Animal Health Ltd., Croatia
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1022 </p>
1023 </div>
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1037 <p style="text-align: justify;">
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1041 </p>
1042 </div>
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1055 <div align="justify">
1056 <p style="text-align: justify;">
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1058 <b><i>Important note</i></b><b></b>
1059
1060 </p>
1061 </div>
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1074 <div align="justify">
1075 <p style="text-align: justify;">
1076
1077 Infectious bursal disease virus (Gumboro disease) affects bursa of Fabricius, which is an important part of the chicks' immune system. Its infection markedly affects the bird's resistance to infectious diseases, particularly if occurs during the first 2 weeks of hatching. Infected chicks may have reduced immune response to other avian vaccines.
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1079 </p>
1080 </div>
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1094 <p style="text-align: justify;">
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1098 </p>
1099 </div>
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1112 <div align="justify">
1113 <p style="text-align: justify;">
1114
1115 In every animal population there are some with poorer response to vaccination. In addition to proper storage and administration, success of vaccination depends on hereditary factors, age of the animal, subclinical diseases, maternal antibodies, feed, stress factors and concurrent administration of other drugs.
1116
1117 </p>
1118 </div>
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1136 </p>
1137 </div>
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1150 <div align="left">
1151 <p style="text-align: left;">
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1155 </p>
1156 </div>
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1162
1163
1164 <!--Section Ends-->
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