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1 <p><b>Continued Strong Growth of Zithromax (Azithromycin) Sales</b></p>
2 <p>Zagreb, 20th April 1999</p>
3 <p>"Global sales of Zithromax (azithromycin), a broad-spectrum oral antibiotic
4 increased by 44 percent to US$ 441 million in the first quarter of 1999", Pfizer
5 reported last week. "Growth in sales resulted form physicians' increasing recognition
6 of the product's broad efficacy, compliance advantages, favourable side-effect
7 profile and, in liquid formulation for children, a pleasant taste. Zithromax
8 continues to be the most prescribed brand-name prescription antibiotic in the
9 U.S." added Pfizer in its Press Release.</p>
10 <p>Azithromycin (the active substance of Zithromax) is PLIVA's original antibiotic
11 patented in 1981. In 1987 PLIVA licensed azithromycin to Pfizer for the markets
12 of North and South America, Western Europe and Japan, while PLIVA retained rights
13 to sell this product under its brand name Sumamed in the markets of Central
14 and Eastern Europe. Both companies have rights to sell in China. PLIVA earns
15 a royalty on all Pfizer sales of Zithromax.</p>
16 <table width="75%" border="0" align="center">
17 <tr>
18 <td colspan="4">
19 <div align="center"><b>Table: Zithromax sales Q1 1999 / Q1 1998</b></div>
20 </td>
21 </tr>
22 <tr>
23 <td>
24 <div align="center"><b>(US$ m.)</b></div>
25 </td>
26 <td>
27 <div align="center"><b>Q1 1999 </b></div>
28 </td>
29 <td>
30 <div align="center"><b>Q1 1998 </b></div>
31 </td>
32 <td>
33 <div align="center"><b>Change (%) </b></div>
34 </td>
35 </tr>
36 <tr>
37 <td>
38 <div align="center">USA</div>
39 </td>
40 <td>
41 <div align="center">344</div>
42 </td>
43 <td>
44 <div align="center">232</div>
45 </td>
46 <td>
47 <div align="center">48</div>
48 </td>
49 </tr>
50 <tr>
51 <td>
52 <div align="center">Rest of the World</div>
53 </td>
54 <td>
55 <div align="center">97</div>
56 </td>
57 <td>
58 <div align="center">74</div>
59 </td>
60 <td>
61 <div align="center">32</div>
62 </td>
63 </tr>
64 <tr>
65 <td>
66 <div align="center"><b>Total</b></div>
67 </td>
68 <td>
69 <div align="center"><b>441 </b></div>
70 </td>
71 <td>
72 <div align="center"><b>306</b></div>
73 </td>
74 <td>
75 <div align="center"><b>44</b></div>
76 </td>
77 </tr>
78 </table>

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